{"id":17091,"date":"2014-12-10T16:08:54","date_gmt":"2014-12-10T15:08:54","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?page_id=17091"},"modified":"2026-01-16T14:26:27","modified_gmt":"2026-01-16T13:26:27","slug":"biomimetic-systems-for-cell-engineering","status":"publish","type":"page","link":"https:\/\/ibecbarcelona.eu\/es\/biomsyscelleng","title":{"rendered":"Biomimetic systems for cell engineering"},"content":{"rendered":"\n
The Biomimetic systems for cell engineering group is a junior group under IBEC’s Tenure Track scheme.<\/address>\n\n\n
\n

About<\/h2>\n
\n\n\n\n\n

The \u201cBiomimetic Systems for Cell Engineering\u201d group is a multidisciplinary research group focussing its research activities on the development and application of new artificial systems that mimic tissue micro and nanofeatures for biomimetic in vitro assays.<\/span><\/span><\/h4>\n\n\n\n
\n

The use of more biomimetic and complex 3D models in in vitro assays is now a hot and extremely relevant topic. <\/p>\n<\/blockquote>\n\n\n\n

\u201cFlat biology\u201d results are questioned when being transferred to in vivo, while the pressure to decrease animal testing continues increasing. As a group of engineering providers working in the biotechnological field, we see these issues as both a challenge and a clear opportunity to impact the field with novel technological solutions. Our research ambition will be to develop better engineering tools to help in the development of organotypic cell culture models, easy to implement in daily cell culture routines, so they have a real and meaningful impact in the biotechnological arena and, therefore, will impact applications in basic cell research, disease modelling and regenerative medicine. <\/p>\n\n\n\n

Along with this line, we are working towards the following objectives: (i) to engineer and validate a complex in vitro model of small intestinal epithelium, (ii) to validate a novel in vitro model of engineered cardiac tissue and (iii) to engineer a novel vessel-on-chip to reproduce the tumor metastatic environment. To carry out our research we employ cutting edge biofabrication technologies such as bioprinting and novel biological tools such as organoids.<\/p>\n\n\n\n

\n
\"\"
The caption is: Mimicking small intestinal tissue by culturing intestinal-organoid derived cells on poly(ethylene glycol) diacrylate (PEGDA) microstructures. Cell nuclei are stained in green and actin cytoskeleton in re<\/figcaption><\/figure>\n<\/figure>\n\n\n\n
 <\/div>\n\n\n\n<\/div>

Staff<\/h2>\n
\n\n\n\n