{"id":102215,"date":"2022-11-22T10:09:00","date_gmt":"2022-11-22T09:09:00","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=102215"},"modified":"2022-12-07T17:18:04","modified_gmt":"2022-12-07T16:18:04","slug":"ibec-organizes-the-i-conference-on-bioengineering-for-neuromuscular-diseases","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/ibec-organizes-the-i-conference-on-bioengineering-for-neuromuscular-diseases\/","title":{"rendered":"El IBEC organiza la I Jornada de Bioingenier\u00eda para Enfermedades Neuromusculares\u00a0"},"content":{"rendered":"\n

El pasado d\u00eda 15 de noviembre se celebr\u00f3 el D\u00eda Mundial de las Enfermedades Neuromusculares. Coincidiendo con la fecha, el IBEC organiz\u00f3 dos eventos que reunieron a cient\u00edficos y pacientes para hablar de los nuevos enfoques que la bioingenier\u00eda puede aportar para el diagn\u00f3stico y tratamiento de estas enfermedades minoritarias.  <\/h4>\n\n\n\n

A pesar de ser consideradas como enfermedades raras o minoritarias, ya se han descrito hasta la fecha m\u00e1s de 150 enfermedades neuromusculares, e infelizmente la gran mayor\u00eda no dispone de metodolog\u00edas de diagn\u00f3stico adecuadas ni de cura. Los pacientes solo cuentan con tratamientos paliativos para reducir los s\u00edntomas. En la mayor\u00eda de los casos el origen es gen\u00e9tico y muchas adem\u00e1s son hereditarias. Aunque var\u00edan en la causa y los s\u00edntomas, todas se caracterizan por una mayor debilidad muscular que se traduce en la p\u00e9rdida de movilidad y de la capacidad motora de los pacientes. Dentro de este gran grupo de enfermedades se incluyen la esclerosis lateral amiotr\u00f3fica (ELA), la distrofia muscular de Duchenne y varias miopat\u00edas, par\u00e1lisis musculares, y enfermedades musculares inflamatorias o metab\u00f3licas.  <\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

En este contexto, varias l\u00edneas de investigaci\u00f3n del IBEC buscan aportar, a trav\u00e9s de la bioingenier\u00eda, nuevas herramientas, tanto de diagn\u00f3stico como de tratamiento, para estas enfermedades. El pasado d\u00eda 15 de noviembre el IBEC celebr\u00f3 la I Jornada de Bioingenier\u00eda para Enfermedades Neuromusculares<\/strong>. Reconocidos investigadores del IBEC e invitados de otras instituciones cient\u00edficas mostraron los \u00faltimos avances en la investigaci\u00f3n de enfermedades neuromusculares desde diferentes perspectivas.  <\/p>\n\n\n\n

La Jornada, impulsada por Juanma Fernandez, investigador del grupo \u201cBiosensores para Bioingenier\u00eda<\/a>\u201d, se inaugur\u00f3 con la bienvenida de Josep Samitier, director del IBEC, que resalt\u00f3 la necesidad de buscar nuevos sistemas para mejorar tanto el diagnostico como las terapias en ese \u00e1mbito: \u201cDesde el IBEC utilizamos la bioingenier\u00eda para aportar herramientas para el desarrollo de biomodelos para el estudio, y de nuevas terapias que nos permitan afrontar mejor las enfermedades neuromusculares\u201d<\/em> <\/p>\n\n\n\n

Diferentes investigadores invitados destacaron la necesidad de conocer en profundidad las fisiopat\u00edas espec\u00edficas de las enfermedades neuromusculares para establecer m\u00e9todos claros y fiables para su correcto diagn\u00f3stico. Adem\u00e1s, resaltaron el reto del desarrollo de f\u00e1rmacos o de terapias g\u00e9nicas dirigidos a nuevas dianas terap\u00e9uticas para un tratamiento efectivo.  <\/p>\n\n\n\n

Uno de los enfoques que se presentaron en la Jornada se basa en la utilizaci\u00f3n de la \u201cmutag\u00e9nesis profunda\u201d. Marta Badia, investigadora del grupo de \u201cTransiciones de fase proteica en salud y enfermedad<\/a>\u201d del IBEC, mostr\u00f3 resultados esperanzadores con la utilizaci\u00f3n de esa t\u00e9cnica de cara a establecer patrones de expresi\u00f3n g\u00e9nica y poder realizar un diagn\u00f3stico precoz y preciso del efecto de las mutaciones en el desarrollo de las enfermedades musculares.  <\/p>\n\n\n\n

Josep Samitier y Juanma Fern\u00e1ndez destacaron la necesidad de dise\u00f1ar modelos de estudio alternativos al uso de animales que puedan reproducir estas enfermedades en el laboratorio y poder evaluar el impacto de los f\u00e1rmacos. En este sentido destacaron la t\u00e9cnica de \u201corgan-on-chip\u201d, capaz de reproducir la estructura de un tejido humano a partir de unas pocas c\u00e9lulas cultivadas. Esta t\u00e9cnica es muy \u00fatil no solo para estudiar y conocer mejor las fisiopat\u00edas en s\u00ed, pero tambi\u00e9n porque permite probar f\u00e1rmacos de manera r\u00e1pida y eficiente, adem\u00e1s de ser una t\u00e9cnica de medicina personalizada ya que puede partir de c\u00e9lulas de los propios pacientes.  <\/p>\n\n\n\n

\u201cEn nuestro laboratorio utilizamos nuevas tecnolog\u00edas para desarrollar sistemas de modelos de \u00f3rganos en un chip que nos permitan emular in vitro un proceso fisiol\u00f3gico o fisiopatol\u00f3gico, por ejemplo, en el contexto de enfermedades neuromusculares\u201d Juanma Fern\u00e1ndez <\/h4>\n\n\n\n

La jornada se cerr\u00f3 con la participaci\u00f3n de Marisol Montolio del Olmo, directora del departamento de investigaci\u00f3n y tecnol\u00f3gico de Duchenne Parent Project Espa\u00f1a, que destac\u00f3 la importancia de una detecci\u00f3n precoz de las enfermedades musculares, entre ellas la Distrofia Muscular de Duchenne, y de desarrollar modelos para estudiar el efecto de diferentes mutaciones en la enfermedad. <\/p>\n\n\n\n

El evento fue coorganizado y patrocinado por la C\u00e1tedra UB de Enfermedades Raras<\/a><\/p>\n\n\n\n

<\/div>\n\n\n\n

Evento divulgativo sobre enfermedades neuromusculares<\/strong> <\/strong><\/p>\n\n\n\n

Ligado a esta jornada, el IBEC tambi\u00e9n organiz\u00f3 un evento de divulgaci\u00f3n cient\u00edfica dirigido a pacientes, familiares, asociaciones de pacientes, y a todas las personas interesadas en la investigaci\u00f3n de enfermedades neuromusculares. En este evento de car\u00e1cter m\u00e1s informal, celebrado el s\u00e1bado 19 de noviembre por la ma\u00f1ana, se dio a conocer a los asistentes los diferentes caminos que est\u00e1 tomando la ciencia, y en concreto la bioingenier\u00eda, para investigar en este campo.    <\/p>\n\n\n\n

\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n<\/figure>\n\n\n\n

Durante el evento se organizaron conferencias, talleres y una visita guiada a diferentes laboratorios donde los asistentes vieron de primera mano d\u00f3nde y c\u00f3mo trabajan los investigadores del IBEC.  <\/p>\n","protected":false},"excerpt":{"rendered":"

El pasado d\u00eda 15 de noviembre se celebr\u00f3 el D\u00eda Mundial de las Enfermedades Neuromusculares. Coincidiendo con la fecha, el IBEC organiz\u00f3 dos eventos que reunieron a cient\u00edficos y pacientes … Read more<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1861,1851,1733],"post_formats":[],"class_list":["post-102215","post","type-post","status-publish","format-standard","hentry","category-noticias-institucionales","tag-divulgacion-es","tag-enfermedades-neuromusculares","tag-evento"],"yoast_head":"\nEl IBEC organiza la I Jornada de Bioingenier\u00eda para Enfermedades Neuromusculares\u00a0 - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/ibec-organizes-the-i-conference-on-bioengineering-for-neuromuscular-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El IBEC organiza la I Jornada de Bioingenier\u00eda para Enfermedades Neuromusculares\u00a0 - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"El pasado d\u00eda 15 de noviembre se celebr\u00f3 el D\u00eda Mundial de las Enfermedades Neuromusculares. 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