{"id":121546,"date":"2024-11-15T15:06:58","date_gmt":"2024-11-15T14:06:58","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/viscosity-of-materials-key-to-cell-differentiation\/"},"modified":"2024-11-15T15:13:27","modified_gmt":"2024-11-15T14:13:27","slug":"viscosity-of-materials-key-to-cell-differentiation","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular","title":{"rendered":"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular"},"content":{"rendered":"\n<p><strong>Un estudio liderado por el IBEC ha desvelado c\u00f3mo las c\u00e9lulas madre mesenquimales responden a la viscosidad de su entorno, un aspecto fundamental en su proceso de diferenciaci\u00f3n. Publicado en Nature Communications, esta investigaci\u00f3n aporta nuevos conocimientos que podr\u00edan revolucionar el dise\u00f1o de biomateriales para aplicaciones en medicina regenerativa.<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-1024x683.jpg\" alt=\"\" class=\"wp-image-121529 lazyload\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-1024x683.jpg 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-300x200.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-768x512.jpg 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-600x400.jpg 600w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg 1200w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/683;\" \/><figcaption class=\"wp-element-caption\">De izquierda a derecha: Aleixandre Rodrigo, Manuel Salmeron y Mariana Azevedo en los laboratorios del IBEC.<\/figcaption><\/figure>\n\n\n\n<p>Una investigaci\u00f3n liderada por Manuel Salmeron, profesor de investigaci\u00f3n ICREA en el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y Catedr\u00e1tico de Ingenier\u00eda Biom\u00e9dica en la Universidad de Glasgow, ha avanzado en la comprensi\u00f3n de c\u00f3mo las c\u00e9lulas madre mesenquimales (MSCs) perciben la viscosidad de su entorno, un factor clave para su diferenciaci\u00f3n hacia distintos tipos de tejidos. Este hallazgo, publicado en <em>Nature Communications<\/em>, aporta conocimientos fundamentales que podr\u00edan mejorar el dise\u00f1o de biomateriales para aplicaciones en medicina regenerativa.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>Normalmente, modelamos los tejidos como si fueran muelles. Pero en realidad, los tejidos son viscoel\u00e1sticos, lo que significa que, al aplicarles fuerza, se deforman, y no necesitamos mantener esa fuerza constante para sostener la deformaci\u00f3n, porque su estructura interna se reorganiza.<\/p>\n\n\n\n<p>Manuel Salmeron<\/p>\n<\/blockquote>\n\n\n\n<p>Las MSCs tienen la capacidad de convertirse en diferentes tipos celulares \u2014como c\u00e9lulas de hueso, cart\u00edlago o m\u00fasculo\u2014 y su destino puede depender de las propiedades f\u00edsicas del entorno en el que se encuentran. Hasta ahora, gran parte de la investigaci\u00f3n se centraba en la \u00abrigidez\u00bb de los materiales, sin tener en cuenta la \u00abviscosidad\u00bb.<\/p>\n\n\n\n<p>\u00abNormalmente, modelamos los tejidos como si fueran muelles: necesitamos mantener una fuerza constante para que sigan deformados; cuando soltamos el muelle, este vuelve a su forma original. Pero en realidad, los tejidos son viscoel\u00e1sticos, lo que significa que, al aplicarles fuerza, se deforman, y no necesitamos mantener esa fuerza constante para sostener la deformaci\u00f3n, porque su estructura interna se reorganiza,\u201d explica Manuel Salmeron, l\u00edder del grupo del IBEC <a href=\"https:\/\/ibecbarcelona.eu\/research-groups\/microenvironments-for-medicine\/\">Microambientes para Medicina<\/a> y \u00faltimo autor del estudio.<\/p>\n\n\n\n<p>As\u00ed, para analizar en profundidad c\u00f3mo las propiedades viscosas impactan en el comportamiento celular, el equipo ha dejado a un lado la rigidez y ha trabajado \u00fanicamente con la viscosidad. Concretamente han dise\u00f1ado un modelo experimental con membranas lip\u00eddicas que imitan la viscosidad de los tejidos naturales, permitiendo estudiar c\u00f3mo la interacci\u00f3n entre las prote\u00ednas de adhesi\u00f3n (integrinas) y las prote\u00ednas de conexi\u00f3n celular (cadherinas) modula la interacci\u00f3n de las MSCs con su entorno.<\/p>\n\n\n\n<p>Los resultados muestran que, en presencia de otras c\u00e9lulas, la adhesi\u00f3n de las MSCs al sustrato disminuye, modificando su comportamiento y potenciando su diferenciaci\u00f3n hacia tejidos m\u00e1s blandos como el cart\u00edlago. Tanto la viscosidad de la matriz extracelular como las interacciones entre c\u00e9lulas afectan notablemente a c\u00f3mo las c\u00e9lulas madre perciben su entorno, un factor que deber\u00eda integrarse en el dise\u00f1o de biomateriales.<\/p>\n\n\n\n<p>En colaboraci\u00f3n con el equipo de Pere Roca-Cusachs, catedr\u00e1tico de la Universidad de Barcelona (UB) e investigador principal del grupo de <a href=\"https:\/\/ibecbarcelona.eu\/es\/cellmolmech\">Mecanobiolog\u00eda celular y molecular<\/a> del IBEC, los investigadores han adaptado su modelo anterior para incluir tanto la viscosidad como las interacciones entre c\u00e9lulas mediante cadherinas. Este modelo innovador permite simular de forma m\u00e1s realista el comportamiento de los tejidos viscoel\u00e1sticos en el cuerpo humano.<\/p>\n\n\n\n<p>El estudio es el principal resultado de la tesis doctoral de Eva Barcelona y supone un paso adelante en el desarrollo de materiales que puedan guiar con mayor precisi\u00f3n la regeneraci\u00f3n de tejidos, sentando las bases para una medicina regenerativa m\u00e1s eficiente y personalizada.<\/p>\n\n\n\n<p><a id=\"_msocom_1\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-video\"><video controls src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/DPPC-RGD-and-high-HAVDI.mp4\"><\/video><figcaption class=\"wp-element-caption\">C\u00e9lula madre sobre la superficie modelo de viscosidad controlada utilizadas para simular el contacto c\u00e9lula-c\u00e9lula. El v\u00eddeo muestra el movimiento del citoesqueleto de actina durante el proceso de adhesi\u00f3n celular.<\/figcaption><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>Art\u00edculo referenciado: <\/strong><\/p>\n\n\n\n<p>Eva Barcelona-Estaje, Mariana A. G. Oliva, Finlay Cunniffe, Aleixandre Rodrigo-Navarro, Paul Genever, Matthew J. Dalby, Pere Roca-Cusachs, Marco Cantini &amp; Manuel Salmeron-Sanchez. <strong>N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity. <\/strong><em>Nature Communications, 15, 8824<\/em>(2024). DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41467-024-53107-6\">10.1038\/s41467-024-53107-6<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Un estudio liderado por el IBEC ha desvelado c\u00f3mo las c\u00e9lulas madre mesenquimales responden a la viscosidad de su entorno, un aspecto fundamental en su proceso de diferenciaci\u00f3n. Publicado en Nature Communications, esta investigaci\u00f3n aporta nuevos conocimientos que podr\u00edan revolucionar el dise\u00f1o de biomateriales para aplicaciones en medicina regenerativa.<\/p>\n","protected":false},"author":37,"featured_media":121531,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[1813,2084,2097,1135],"post_formats":[],"class_list":["post-121546","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion","tag-cellular-and-molecular-mechanobiology-es","tag-manuel-salmeron-es","tag-microenvironments-for-medicine-es","tag-pere-roca-cusachs-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Un estudio liderado por el IBEC ha desvelado c\u00f3mo las c\u00e9lulas madre mesenquimales responden a la viscosidad de su entorno, un aspecto fundamental en su proceso de diferenciaci\u00f3n. Publicado en Nature Communications, esta investigaci\u00f3n aporta nuevos conocimientos que podr\u00edan revolucionar el dise\u00f1o de biomateriales para aplicaciones en medicina regenerativa.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-15T14:06:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-15T14:13:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Sarah Moreira\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sarah Moreira\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/\"},\"author\":{\"name\":\"Sarah Moreira\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/d3a158b8d448000777023ca1e3d71d34\"},\"headline\":\"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular\",\"datePublished\":\"2024-11-15T14:06:58+00:00\",\"dateModified\":\"2024-11-15T14:13:27+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/\"},\"wordCount\":712,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg\",\"keywords\":[\"Cellular and molecular mechanobiology\",\"Manuel Salmer\u00f3n\",\"Microenvironments for Medicine\",\"Pere Roca-Cusachs\"],\"articleSection\":[\"Noticias de investigaci\u00f3n\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/\",\"name\":\"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular - Institute for Bioengineering of Catalonia\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg\",\"datePublished\":\"2024-11-15T14:06:58+00:00\",\"dateModified\":\"2024-11-15T14:13:27+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg\",\"contentUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg\",\"width\":1200,\"height\":800},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#website\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/\",\"name\":\"Institute for Bioengineering of Catalonia\",\"description\":\"Bioengineering solutions for health\",\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ibecbarcelona.eu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\",\"name\":\"Institute for Bioengineering of Catalonia\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/cropped-IBEC_20ANYS_GRIS.png\",\"contentUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/cropped-IBEC_20ANYS_GRIS.png\",\"width\":696,\"height\":257,\"caption\":\"Institute for Bioengineering of Catalonia\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/d3a158b8d448000777023ca1e3d71d34\",\"name\":\"Sarah Moreira\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/37385a1f83bdef106d1b89522da4c620ee48ba2eb0662dbc73ba05b7f3fbdf89?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/37385a1f83bdef106d1b89522da4c620ee48ba2eb0662dbc73ba05b7f3fbdf89?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/37385a1f83bdef106d1b89522da4c620ee48ba2eb0662dbc73ba05b7f3fbdf89?s=96&d=mm&r=g\",\"caption\":\"Sarah Moreira\"},\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/author\\\/smoreira\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular - Institute for Bioengineering of Catalonia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/","og_locale":"es_ES","og_type":"article","og_title":"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular - Institute for Bioengineering of Catalonia","og_description":"Un estudio liderado por el IBEC ha desvelado c\u00f3mo las c\u00e9lulas madre mesenquimales responden a la viscosidad de su entorno, un aspecto fundamental en su proceso de diferenciaci\u00f3n. Publicado en Nature Communications, esta investigaci\u00f3n aporta nuevos conocimientos que podr\u00edan revolucionar el dise\u00f1o de biomateriales para aplicaciones en medicina regenerativa.","og_url":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/","og_site_name":"Institute for Bioengineering of Catalonia","article_published_time":"2024-11-15T14:06:58+00:00","article_modified_time":"2024-11-15T14:13:27+00:00","og_image":[{"width":1200,"height":800,"url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg","type":"image\/jpeg"}],"author":"Sarah Moreira","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"Sarah Moreira","Tiempo de lectura":"3 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#article","isPartOf":{"@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/"},"author":{"name":"Sarah Moreira","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/person\/d3a158b8d448000777023ca1e3d71d34"},"headline":"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular","datePublished":"2024-11-15T14:06:58+00:00","dateModified":"2024-11-15T14:13:27+00:00","mainEntityOfPage":{"@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/"},"wordCount":712,"publisher":{"@id":"https:\/\/ibecbarcelona.eu\/#organization"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#primaryimage"},"thumbnailUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg","keywords":["Cellular and molecular mechanobiology","Manuel Salmer\u00f3n","Microenvironments for Medicine","Pere Roca-Cusachs"],"articleSection":["Noticias de investigaci\u00f3n"],"inLanguage":"es"},{"@type":"WebPage","@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/","url":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/","name":"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular - Institute for Bioengineering of Catalonia","isPartOf":{"@id":"https:\/\/ibecbarcelona.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#primaryimage"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#primaryimage"},"thumbnailUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg","datePublished":"2024-11-15T14:06:58+00:00","dateModified":"2024-11-15T14:13:27+00:00","breadcrumb":{"@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#primaryimage","url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg","contentUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg","width":1200,"height":800},{"@type":"BreadcrumbList","@id":"https:\/\/ibecbarcelona.eu\/es\/la-viscosidad-de-los-materiales-clave-en-la-diferenciacion-celular\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ibecbarcelona.eu\/es\/"},{"@type":"ListItem","position":2,"name":"La viscosidad de los materiales, clave en la diferenciaci\u00f3n celular"}]},{"@type":"WebSite","@id":"https:\/\/ibecbarcelona.eu\/#website","url":"https:\/\/ibecbarcelona.eu\/","name":"Institute for Bioengineering of Catalonia","description":"Bioengineering solutions for health","publisher":{"@id":"https:\/\/ibecbarcelona.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ibecbarcelona.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/ibecbarcelona.eu\/#organization","name":"Institute for Bioengineering of Catalonia","url":"https:\/\/ibecbarcelona.eu\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/logo\/image\/","url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/01\/cropped-IBEC_20ANYS_GRIS.png","contentUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/01\/cropped-IBEC_20ANYS_GRIS.png","width":696,"height":257,"caption":"Institute for Bioengineering of Catalonia"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/person\/d3a158b8d448000777023ca1e3d71d34","name":"Sarah Moreira","image":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/secure.gravatar.com\/avatar\/37385a1f83bdef106d1b89522da4c620ee48ba2eb0662dbc73ba05b7f3fbdf89?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/37385a1f83bdef106d1b89522da4c620ee48ba2eb0662dbc73ba05b7f3fbdf89?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/37385a1f83bdef106d1b89522da4c620ee48ba2eb0662dbc73ba05b7f3fbdf89?s=96&d=mm&r=g","caption":"Sarah Moreira"},"url":"https:\/\/ibecbarcelona.eu\/es\/author\/smoreira\/"}]}},"AFP_featured_media_urls":{"full":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg",1200,800,false],"thumbnail":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-150x150.jpg",150,150,true],"medium":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-300x200.jpg",300,200,true],"medium_large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-768x512.jpg",768,512,true],"large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-1024x683.jpg",1024,683,true]},"AFP_attachments":{"full":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low.jpg",1200,800,false],"thumbnail":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-150x150.jpg",150,150,true],"medium":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-300x200.jpg",300,200,true],"medium_large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-768x512.jpg",768,512,true],"large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/11c2c099-7f9e-4e5d-ac22-d1d71d0fb153_low-1024x683.jpg",1024,683,true]},"AFP_videos":{"121534":{"ID":121534,"post_author":"37","post_date":"2024-11-15 15:03:18","post_date_gmt":"2024-11-15 14:03:18","post_content":"","post_title":"DPPC RGD and high HAVDI","post_excerpt":"","post_status":"inherit","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dppc-rgd-and-high-havdi-2","to_ping":"","pinged":"","post_modified":"2024-11-15 15:03:18","post_modified_gmt":"2024-11-15 14:03:18","post_content_filtered":"","post_parent":121546,"guid":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/DPPC-RGD-and-high-HAVDI.mp4","menu_order":0,"post_type":"attachment","post_mime_type":"video\/mp4","comment_count":"0","filter":"raw"},"121535":121534},"AFP_video_blocks":"<figure class=\"wp-block-video\"><video controls src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2024\/11\/DPPC-RGD-and-high-HAVDI.mp4\"><\/video><figcaption class=\"wp-element-caption\">C\u00e9lula madre sobre la superficie modelo de viscosidad controlada utilizadas para simular el contacto c\u00e9lula-c\u00e9lula. El v\u00eddeo muestra el movimiento del citoesqueleto de actina durante el proceso de adhesi\u00f3n celular.<\/figcaption><\/figure>\n","AFP_category_names":["Noticias de investigaci\u00f3n"],"_links":{"self":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts\/121546","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/users\/37"}],"replies":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/comments?post=121546"}],"version-history":[{"count":2,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts\/121546\/revisions"}],"predecessor-version":[{"id":121549,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts\/121546\/revisions\/121549"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/media\/121531"}],"wp:attachment":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/media?parent=121546"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/categories?post=121546"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/tags?post=121546"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/post_formats?post=121546"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}