{"id":126037,"date":"2025-05-27T17:13:56","date_gmt":"2025-05-27T15:13:56","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/ibec-co-organised-the-leading-international-symposium-on-mutational-scanning\/"},"modified":"2025-05-28T11:46:41","modified_gmt":"2025-05-28T09:46:41","slug":"ibec-co-organised-the-leading-international-symposium-on-mutational-scanning","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/ibec-coorganiza-el-simposio-internacional-de-referencia-en-escaneo-mutacional","title":{"rendered":"IBEC coorganiza el simposio internacional de referencia en escaneo mutacional"},"content":{"rendered":"\n

M\u00e1s de 300 personas asistieron la pasada semana a la octava edici\u00f3n del Mutational Scanning Symposium, celebrado <\/em>21 al 23 de mayo en el Parc de Recerca Biom\u00e8dica de Barcelona. Se trata de un evento internacional de referencia para debatir los \u00faltimos avances en tecnolog\u00edas de escaneo mutacional y Ensayos multiplexados sobre el impacto de mutaciones. Este a\u00f1o, el simposio fue coorganizado por el Instituto de Bioingenier\u00eda de Catalu\u00f1a, el Centro de Regulaci\u00f3n Gen\u00f3mica y la iniciativa internacional Atlas of Variant Effects<\/em>.<\/strong><\/a><\/p>\n\n\n\n

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Del 21 al 23 de mayo de 2025, el Parc de Recerca Biom\u00e8dica de Barcelona (PRBB) fue el escenario de la octava edici\u00f3n del Mutational Scanning Symposium (MSS)<\/em>, un evento internacional de referencia que reuni\u00f3 a 250 asistentes presenciales y 60 virtuales, de 20 pa\u00edses distintos, para debatir los \u00faltimos avances en tecnolog\u00edas de escaneo mutacional y Ensayos multiplexados sobre el impacto de mutaciones (MAVEs, por sus siglas en ingl\u00e9s). El simposio fue coorganizado por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC), el Centro de Regulaci\u00f3n Gen\u00f3mica (CRG) y la iniciativa internacional Atlas of Variant Effects<\/em>.<\/p>\n\n\n\n

\u201cEste simposio desempe\u00f1a un papel clave como puente entre la comunidad cient\u00edfica y cl\u00ednica\u201d, afirma Bendetta Bolognesi, investigadora principal en el IBEC y miembro del comit\u00e9 organizador del MSS 2025.<\/p>\n\n\n\n

Durante dos d\u00edas y medio, expertos y expertas en gen\u00f3mica funcional, ciencia de prote\u00ednas, medicina de precisi\u00f3n, gen\u00e9tica computacional, machine learning<\/em> (aprendizaje autom\u00e1tico) e interpretaci\u00f3n de variantes intercambiaron conocimientos, presentaron sus \u00faltimos trabajos y discutieron sobre el futuro de este campo en r\u00e1pida evoluci\u00f3n. El programa incluy\u00f3 m\u00e1s de 30 ponencias cient\u00edficas, sesiones de p\u00f3steres y dos talleres interactivos orientados a la interpretaci\u00f3n de variantes en la pr\u00e1ctica cl\u00ednica y al dise\u00f1o de prote\u00ednas.<\/a><\/p>\n\n\n\n

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Este simposio desempe\u00f1a un papel clave como puente entre la comunidad cient\u00edfica y cl\u00ednica.<\/p>\n\n\n\n

Benedetta Bolognesi<\/p>\n<\/blockquote>\n\n\n\n

Durante dos d\u00edas y medio, expertos y expertas en gen\u00f3mica funcional, ciencia de prote\u00ednas, medicina de precisi\u00f3n, gen\u00e9tica computacional, machine learning<\/em> (aprendizaje autom\u00e1tico) e interpretaci\u00f3n de variantes intercambiaron conocimientos, presentaron sus \u00faltimos trabajos y discutieron sobre el futuro de este campo en r\u00e1pida evoluci\u00f3n. El programa incluy\u00f3 m\u00e1s de 30 ponencias cient\u00edficas, sesiones de p\u00f3steres y dos talleres interactivos orientados a la interpretaci\u00f3n de variantes en la pr\u00e1ctica cl\u00ednica y al dise\u00f1o de prote\u00ednas.<\/p>\n\n\n\n

La jornada cont\u00f3 con ponentes de renombre internacional, como Dave Dams (Wellcome Sanger Institute), Julien Gagneur (Technical University of  Munich), J\u00falia Domingo (ALLO-X), Polly Fordyce (Stanford University), Patrick Hsu (ARC Institute), Ylva Ivarsson (Uppsala University), Kresten Lindorff-Larsen (University of copenhagen), Matthew Coelho (Wellcome Sanger Institute), Pascal Notin (Harvard University), Ju Zheng (BGI Research), Lars Velten (CRG), Nicola Whiffin (University of Oxford), Arvind Kumar (Illumina) y Nobuhiko Tokuriki (The University of British Columbia).<\/p>\n\n\n\n

El IBEC tambi\u00e9n acogi\u00f3 el d\u00eda previo al simposio el primer taller, centrado en la selecci\u00f3n de modelos para la predicci\u00f3n de efectos de variantes y el dise\u00f1o de prote\u00ednas; de la mano de Noelia Ferruz y Albert Escobedo, del CRG, y pascal Notin, de la Universidad de Harvard. El evento finaliz\u00f3 el 23 de mayo con un segundo taller orientado a la transferencia de datos funcionales hacia el \u00e1mbito cl\u00ednico, poniendo \u00e9nfasis en c\u00f3mo compartir conjuntos de datos MAVEs de forma \u00fatil para profesionales de la salud; de la mano de Lea Starita, Abbye Mcewen y Malvika Tejura, de la Universidad de Washington y Alan Rubin, del Walter and Eliza Hall Institute.<\/a><\/p>\n\n\n\n

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Ju Zheng (BGI Research)<\/figcaption><\/figure>\n\n\n\n
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J\u00falia Domingo (ALLO-X)<\/figcaption><\/figure>\n\n\n\n
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Andrew Glazer (Vanderbilt University Medical Center)<\/figcaption><\/figure>\n\n\n\n
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Entre los temas tratados destacaron la interpretaci\u00f3n funcional de variantes gen\u00e9ticas, las relaciones entre secuencia y estructura de prote\u00ednas, la inteligencia artificial aplicada al dise\u00f1o de prote\u00ednas y el modelado biof\u00edsico. Adem\u00e1s, el simposio ofreci\u00f3 una panor\u00e1mica de las tecnolog\u00edas emergentes en s\u00edntesis de ADN, mutag\u00e9nesis de saturaci\u00f3n y un enfoque importante en los \u00faltimos modelos de machine learning<\/em> aplicados a la investigaci\u00f3n biom\u00e9dica.<\/p>\n\n\n\n

El \u00e9xito de asistencia y participaci\u00f3n consolid\u00f3 este encuentro como una plataforma de referencia global para investigadores e investigadoras que trabajan en la comprensi\u00f3n funcional del genoma humano y su impacto en la salud de cada individuo. La edici\u00f3n de este a\u00f1o ha contado con el apoyo de entidades l\u00edderes del sector como Twist Bioscience, BioMarin la Chan Zuckerberg Initiative, Illumina, Brotman Baty Institute, AstraZeneca, Constantiam Biosciences, CaixaBank y GCATbio.<\/p>\n\n\n\n

El IBEC, como instituci\u00f3n coorganizadora, reafirma su compromiso con la investigaci\u00f3n interdisciplinar y su papel destacado en la vanguardia internacional de la bioingenier\u00eda y la gen\u00f3mica funcional.<\/a><\/p>\n\n\n\n

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Comit\u00e9 organizador (de izquierda a derecha): Lea Starita (Univeristy of Washington), Mafalda Dias (CRG), Lara Muffley (University of Washington), Benedetta Bolognesi (IBEC), Ben Lehner (CRG) and Jonathan Frazer (CRG).<\/figcaption><\/figure>\n<\/figure>\n","protected":false},"excerpt":{"rendered":"

M\u00e1s de 300 personas asistieron la pasada semana a la octava edici\u00f3n del Mutational Scanning Symposium, celebrado 21 al 23 de mayo en el Parc de Recerca Biom\u00e8dica de Barcelona. Se trata de un evento internacional de referencia para debatir los \u00faltimos avances en tecnolog\u00edas de escaneo mutacional y Ensayos multiplexados sobre el impacto de mutaciones . Este a\u00f1o, el simposio fue coorganizado por el Instituto de Bioingenier\u00eda de Catalu\u00f1a, el Centro de Regulaci\u00f3n Gen\u00f3mica y la iniciativa internacional Atlas of Variant Effects.<\/p>\n","protected":false},"author":37,"featured_media":125998,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1108,1733,1870],"post_formats":[],"class_list":["post-126037","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-benedetta-bolognesi-es","tag-evento","tag-mutaciones-geneticas"],"yoast_head":"\nIBEC coorganiza el simposio internacional de referencia en escaneo mutacional - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/ibec-coorganiza-el-simposio-internacional-de-referencia-en-escaneo-mutacional\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IBEC coorganiza el simposio internacional de referencia en escaneo mutacional - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"M\u00e1s de 300 personas asistieron la pasada semana a la octava edici\u00f3n del Mutational Scanning Symposium, celebrado 21 al 23 de mayo en el Parc de Recerca Biom\u00e8dica de Barcelona. 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