{"id":126074,"date":"2025-05-28T16:13:10","date_gmt":"2025-05-28T14:13:10","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/ibec-receives-funding-from-the-prestigious-human-frontier-science-program\/"},"modified":"2025-05-28T16:20:08","modified_gmt":"2025-05-28T14:20:08","slug":"ibec-receives-funding-from-the-prestigious-human-frontier-science-program","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/el-ibec-recibe-financiacion-del-prestigioso-human-frontier-science-program","title":{"rendered":"El IBEC recibe financiaci\u00f3n del prestigioso Human Frontier Science Program"},"content":{"rendered":"\n

El Instituto de Bioingenier\u00eda de Catalu\u00f1a participar\u00e1 como socio en el proyecto internacional SOLFEGE, que busca explorar c\u00f3mo distintos tipos celulares se coordinan a trav\u00e9s de factores solubles en el microambiente tumoral. El proyecto ser\u00e1 posible gracias a la financiaci\u00f3n del prestigioso \u201cHuman Frontier Science Program\u201d. SOLFEGE es un consorcio coordinado por el Centro Alem\u00e1n de Investigaci\u00f3n Oncol\u00f3gica (DKFZ), y cuenta tambi\u00e9n con la participaci\u00f3n de la Universidad de Duke, en Estados Unidos.<\/strong><\/p>\n\n\n\n

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<\/div>\n\n\n\n

El Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) participar\u00e1 como socio en el proyecto internacional SOLFEGE (acr\u00f3nimo en ingl\u00e9s de Soluble Factors and Cell Arrangements<\/em>) que tiene como objetivo investigar c\u00f3mo distintos tipos celulares se coordinan mediante se\u00f1ales secretadas <\/del>\u2014los llamados factores solubles\u2014 en el microambiente tumoral. Xavier Rovira Clav\u00e9, investigador principal del grupo de Biotecnolog\u00eda Espacial<\/a> del IBEC, liderar\u00e1 la participaci\u00f3n del centro en este ambicioso proyecto.<\/a><\/p>\n\n\n\n

\n

Es un proyecto ambicioso que nos puede contestar a preguntas fundamentales hasta ahora sin respuesta sobre el c\u00e1ncer.<\/p>\n\n\n\n

Xavier Rovira Clav\u00e9<\/p>\n<\/blockquote>\n\n\n\n

SOLFEGE<\/a> ha sido financiado por el Human Frontier Science Program (HFSP)<\/a>, uno de los programas internacionales m\u00e1s prestigiosos y competitivos de apoyo a la investigaci\u00f3n. Este programa promueve la colaboraci\u00f3n interdisciplinaria para explorar los complejos mecanismos de los organismos vivos. El proyecto est\u00e1 coordinado por el Centro Alem\u00e1n de Investigaci\u00f3n Oncol\u00f3gica (DKFZ) y cuenta con la participaci\u00f3n del IBEC y de la Universidad de Duke, en Estados Unidos.<\/p>\n\n\n\n

\u201cEs un proyecto ambicioso que nos puede contestar a preguntas fundamentales hasta ahora sin respuesta sobre el c\u00e1ncer\u201d, comenta Xavier Rovira. \u201cGracias al apoyo del HFSP, durante los pr\u00f3ximos tres a\u00f1os trabajaremos junto al grupo de John Hickey en la Universidad de Duke y al grupo de Franzi Blaeschke en el DKFZ para explorar c\u00f3mo se coordinan distintos tipos celulares a trav\u00e9s de factores solubles dentro del contexto del microambiente tumoral.\u201d<\/p>\n\n\n\n

Desde el IBEC se valora especialmente el reconocimiento que supone recibir esta financiaci\u00f3n internacional tan selectiva, ya que el HFSP se trata de un programa muy prestigioso y competitivo.<\/a><\/p>\n\n\n\n

Coordinaci\u00f3n celular mediante factores solubles<\/strong><\/h4>\n\n\n\n

En nuestro organismo, las c\u00e9lulas se autoorganizan para formar tejidos y \u00f3rganos que permiten la vida. Este proceso est\u00e1 guiado por factores solubles, como las citocinas, quimiocinas y factores de crecimiento, que ayudan a las c\u00e9lulas a saber qu\u00e9 hacer y d\u00f3nde ubicarse. Aunque en ocasiones uno de estos factores puede inducir una acci\u00f3n concreta en una c\u00e9lula, la mayor\u00eda de las funciones biol\u00f3gicas y enfermedades resultan de combinaciones complejas de estos factores que interact\u00faan entre s\u00ed, muchas veces de formas que a\u00fan no se comprenden del todo.<\/p>\n\n\n\n

El proyecto SOLFEGE tiene como objetivo desentra\u00f1ar c\u00f3mo act\u00faan estas redes de se\u00f1ales en conjunto, especialmente en entornos tumorales. Para lograrlo, los investigadores desarrollar\u00e1n nuevas herramientas experimentales, como c\u00f3digos de barras celulares, part\u00edculas liberadoras de factores solubles y modelos computacionales, que permitir\u00e1n observar c\u00f3mo los factores solubles influyen en la organizaci\u00f3n de las c\u00e9lulas inmunitarias y cancerosas.<\/p>\n\n\n\n

Concretamente, estudiar\u00e1n c\u00f3mo se organizan las c\u00e9lulas inmunitarias en organoides tumorales de melanoma expuestos a factores solubles espec\u00edficos; c\u00f3mo act\u00faan part\u00edculas dise\u00f1adas para liberar estos factores; y c\u00f3mo las se\u00f1ales emitidas por c\u00e9lulas T especializadas coordinan los procesos celulares en el microambiente tumoral.<\/p>\n\n\n\n

Gracias a su experiencia en t\u00e9cnicas de imagen avanzada, an\u00e1lisis espacial, biomateriales y modelizaci\u00f3n, el equipo del IBEC contribuir\u00e1 a avanzar en la comprensi\u00f3n de la organizaci\u00f3n celular y de su impacto en el desarrollo de nuevas terapias frente al c\u00e1ncer.<\/a><\/p>\n\n\n\n

Este proyecto ha sido financiado por Human Frontier Science Program<\/em> con una \u201cResearch Grant \u2013 Early Career\u201d (RGEC26\/2025).<\/pre>\n\n\n\n
\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"
El Instituto de Bioingenier\u00eda de Catalu\u00f1a participar\u00e1 como socio en el proyecto internacional SOLFEGE, que busca explorar c\u00f3mo distintos tipos celulares se coordinan a trav\u00e9s de factores solubles en el microambiente tumoral. El proyecto ser\u00e1 posible gracias a la financiaci\u00f3n del prestigioso \u201cHuman Frontier Science Program\u201d. SOLFEGE es un consorcio coordinado por el Centro Alem\u00e1n de Investigaci\u00f3n Oncol\u00f3gica (DKFZ), y cuenta tambi\u00e9n con la participaci\u00f3n de la Universidad de Duke, en Estados Unidos.<\/p>\n","protected":false},"author":37,"featured_media":126071,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1775,2135,2040,2094,2083],"post_formats":[],"class_list":["post-126074","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-cancer-es","tag-eu-project-es-2","tag-european-projects-es","tag-spatial-biotechnology-es","tag-xavier-rovira-es"],"yoast_head":"\nEl IBEC recibe financiaci\u00f3n del prestigioso Human Frontier Science Program - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/el-ibec-recibe-financiacion-del-prestigioso-human-frontier-science-program\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El IBEC recibe financiaci\u00f3n del prestigioso Human Frontier Science Program - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"El Instituto de Bioingenier\u00eda de Catalu\u00f1a participar\u00e1 como socio en el proyecto internacional SOLFEGE, que busca explorar c\u00f3mo distintos tipos celulares se coordinan a trav\u00e9s de factores solubles en el microambiente tumoral. 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