{"id":128948,"date":"2025-10-09T10:00:00","date_gmt":"2025-10-09T08:00:00","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=128948"},"modified":"2025-10-09T10:01:03","modified_gmt":"2025-10-09T08:01:03","slug":"ibec-one-of-the-centres-selected-by-the-pasqual-maragall-foundation-for-its-research-grants","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/ibec-uno-de-los-centros-seleccionados-por-la-fundacion-pasqual-maragall-para-sus-ayudas-a-la-investigacion","title":{"rendered":"El IBEC, uno de los centros seleccionados por la Fundaci\u00f3n Pasqual Maragall para sus ayudas a la investigaci\u00f3n"},"content":{"rendered":"\n

Amayra Hern\u00e1ndez-Vega, investigadora s\u00e9nior del IBEC, liderar\u00e1 uno de los dos proyectos seleccionados en la convocatoria 2024 del Pasqual Maragall Researchers Programme, dedicada a financiar investigaciones sobre el Alzheimer y otras enfermedades neurodegenerativas. Adem\u00e1s, el IBEC celebra la participaci\u00f3n de Jordi Duran, investigador asociado vinculado al grupo de Neurobiotecnolog\u00eda Molecular y Celular del instituto, como colaborador en el segundo proyecto seleccionado.<\/strong><\/a><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n
<\/div>\n\n\n\n

El programa de ayudas Pasqual Maragall Researchers Programme (PMRP) de la Fundaci\u00f3n Pasqual Maragall, financia proyectos de investigaci\u00f3n traslacional o cl\u00ednica de excelencia sobre el Alzheimer u otras enfermedades neurodegenerativas relacionadas con la edad.<\/p>\n\n\n\n

Recientemente se han dado a conocer los dos proyectos seleccionados en la edici\u00f3n 2024, que cuenta con el apoyo de la Fundaci\u00f3n Adey. Es especialmente destacable que ambos incluyen la participaci\u00f3n de personal vinculado al Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC).<\/a><\/p>\n\n\n\n

Estudio de la Tau en la fase inicial<\/strong><\/h4>\n\n\n
\n
\"\"
Amayra Hern\u00e1ndez-Vega<\/figcaption><\/figure><\/div>\n\n\n

Por un lado, Amayra Hern\u00e1ndez-Vega<\/a>, investigadora s\u00e9nior del grupo de Bi\u00f3nica Molecular del IBEC<\/a>, liderar\u00e1 el proyecto MAPtoAD: Estudio de la Tau en la fase inicial de su transici\u00f3n de prote\u00edna asociada a microt\u00fabulos a fibras s\u00f3lidas para el tratamiento precoz de la enfermedad de Alzheimer (EA).<\/p>\n\n\n\n

\n

Durante d\u00e9cadas, la investigaci\u00f3n en Alzheimer se ha centrado principalmente en las fases sintom\u00e1ticas de la enfermedad. El apoyo a este proyecto refleja la visi\u00f3n pionera de la Fundaci\u00f3n en lo que creemos que representa un cambio de paradigma en la estrategia terap\u00e9utica<\/em>.<\/p>\n\n\n\n

Amayra Hern\u00e1ndez-Vega<\/p>\n<\/blockquote>\n\n\n\n

Se centrar\u00e1 en las fases m\u00e1s tempranas del Alzheimer, cuando la prote\u00edna tau, clave en la estructura neuronal, cambia su comportamiento y forma agregados patol\u00f3gicos. Con la colaboraci\u00f3n de la Dra. Natalia Rodr\u00edguez-Muela, del Centro Alem\u00e1n de Enfermedades Neurodegenerativas (DZNE), el equipo desarrollar\u00e1 modelos reconstituidos in vitro<\/em> y modelos humanos de Alzheimer familiar para identificar factores desencadenantes asociados a la edad e inhibidores que prevengan esta transici\u00f3n, con el fin de dise\u00f1ar estrategias de intervenci\u00f3n precoz antes de la aparici\u00f3n de s\u00edntomas cl\u00ednicos.<\/p>\n\n\n\n

\u201cDurante d\u00e9cadas, la investigaci\u00f3n en Alzheimer se ha centrado principalmente en las fases sintom\u00e1ticas de la enfermedad. El apoyo a este proyecto refleja la visi\u00f3n pionera de la Fundaci\u00f3n en lo que creemos que representa un cambio de paradigma en la estrategia terap\u00e9utica\u201d<\/em>, a\u00f1ade Amayra Hern\u00e1ndez-Vega.<\/p>\n\n\n\n

<\/div>\n\n\n\n

Reconocimiento selectivo de los astrocitos<\/strong><\/h4>\n\n\n\n

Por otra parte, Jordi Duran, investigador principal y profesor asociado en el Instituto Qu\u00edmico de Sarri\u00e0 (IQS) \u2013 Universidad Ramon Llull (URL), ser\u00e1 colaborador en el proyecto STAR-AD: Reconocimiento selectivo de los astrocitos: reprogramaci\u00f3n metab\u00f3lica en la enfermedad de Alzheimer, liderado por la profesora Maite Solas, de la Universidad de Navarra (UNAV). Aunque el IBEC no participa directamente en este proyecto, se congratula de la implicaci\u00f3n de Duran, investigador asociado al grupo de Neurobiotecnolog\u00eda Molecular y Celular del IBEC<\/a>.<\/p>\n\n\n\n

El proyecto se centrar\u00e1 en comprender c\u00f3mo los astrocitos, unas c\u00e9lulas esenciales para el correcto funcionamiento del cerebro, modifican su metabolismo en el contexto del Alzheimer y c\u00f3mo estos cambios afectan a procesos clave como la se\u00f1alizaci\u00f3n de la insulina o el almacenamiento de gluc\u00f3geno. El equipo pretende averiguar si intervenir en estas rutas metab\u00f3licas podr\u00eda ralentizar la progresi\u00f3n de la enfermedad o incluso revertirla en sus etapas iniciales.<\/p>\n\n\n\n

La participaci\u00f3n del IBEC en este tipo de proyectos subraya su firme compromiso con la investigaci\u00f3n en enfermedades neurodegenerativas. Desde un enfoque interdisciplinar, el instituto trabaja para comprender los mecanismos fundamentales que subyacen a patolog\u00edas como el Alzheimer y para impulsar nuevas estrategias diagn\u00f3sticas y terap\u00e9uticas que mejoren la calidad de vida de las personas afectadas y de sus familias.<\/p>\n\n\n\n

M\u00e1s informaci\u00f3n sobre los proyectos en la web de la Fundaci\u00f3n Pasqual Maragall.<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Amaya Hern\u00e1ndez-Vega, a senior researcher at IBEC, will lead one of the two projects selected in the 2024 call for proposals from the Pasqual Maragall Research Programme, which is dedicated to funding research into Alzheimer’s disease and other neurodegenerative conditions. IBEC also celebrates the participation of Jordi Duran, an associate researcher from the Molecular and Cellular Neurobiotechnology group, who will collaborate on the second selected project.<\/p>\n","protected":false},"author":37,"featured_media":128927,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1628,1106,1133,1583,2002],"post_formats":[],"class_list":["post-128948","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-alzheimer-es-2","tag-giuseppe-battaglia-es","tag-jose-antonio-del-rio-es","tag-molecular-and-cellular-neurobiotechnology-group-es","tag-molecular-bionics-es"],"yoast_head":"\nEl IBEC, uno de los centros seleccionados por la Fundaci\u00f3n Pasqual Maragall para sus ayudas a la investigaci\u00f3n - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/ibec-uno-de-los-centros-seleccionados-por-la-fundacion-pasqual-maragall-para-sus-ayudas-a-la-investigacion\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El IBEC, uno de los centros seleccionados por la Fundaci\u00f3n Pasqual Maragall para sus ayudas a la investigaci\u00f3n - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Amaya Hern\u00e1ndez-Vega, a senior researcher at IBEC, will lead one of the two projects selected in the 2024 call for proposals from the Pasqual Maragall Research Programme, which is dedicated to funding research into Alzheimer's disease and other neurodegenerative conditions. 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