{"id":23524,"date":"2016-06-23T09:46:57","date_gmt":"2016-06-23T07:46:57","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=23524"},"modified":"2016-07-07T12:40:48","modified_gmt":"2016-07-07T10:40:48","slug":"micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\/","title":{"rendered":"Micobacterias en aceite de oliva para el tratamiento del c\u00e1ncer"},"content":{"rendered":"

\u2013 la aplicaci\u00f3n directa de medicamento mediante degoteo -en pacientes con c\u00e1ncer de vejiga.\u00a0Esta formaci\u00f3n de grumos puede interferir con la interacci\u00f3n de las c\u00e9lulas micobacterias i las c\u00e9lulas del organismo y disminuir los efectos antitumorales.<\/p>\n

Despu\u00e9s de anunciar el descubrimiento, el a\u00f1o pasado, que las c\u00e9lulas de Mycobacterium brumae <\/em>ofrece una alternativa que mejora los tratamientos actuales para el c\u00e1ncer de vejiga, como el BCG que puede causar infecciones, los colaboradores \u2013 liderados por Esther Juli\u00e1n en la UAB \u2013 han buscado la manera para mejorar la actividad inmunoterapeutica de M. Brumae<\/em>. Para ello, han dise\u00f1ado diferentes emulsiones que pueden aumentar la homogeneidad y la estabilidad, y por lo tanto la eficacia, de las soluciones de Mycobacterium<\/em> cuando se introduce en el cuerpo.<\/p>\n

\u00abDe las emulsiones que probamos, la que est\u00e1 basada en el aceite de oliva induce una respuesta inmune importante tanto in vitro<\/em> como in vivo<\/em>. Adem\u00e1s esta emulsi\u00f3n se caracteriza por conservar la viabilidad de las micobacterias y proporcionar tasas de anti-aglutinaci\u00f3n m\u00e1s altas, estas caracter\u00edsticas indican que las condiciones son favorables para alcanzar el epitelio de la vejiga\u00bb, dice Eduard Torrents, responsable de grupo del IBEC, que contribuy\u00f3 al estudio. \u00abLos resultados ponen de manifiesto el potencial de esta emulsi\u00f3n a base de aceite de oliva como un veh\u00edculo de suministro prometedor para el tratamiento con micobacterias de c\u00e1ncer de vejiga.\u00bb<\/p>\n

El trabajo ha sido llevado a cabo por investigadores del Departamento de Gen\u00e9tica y Microbiolog\u00eda de la Facultad de Ciencias Biol\u00f3gicas, del Departamento de Medicina y Cirug\u00eda Animal de la Facultad de Veterinaria, y del Servicio de Microbiolog\u00eda de la UAB, y el grupo de Eduard Torrents, Infecciones Bacterianas: Terapias antimicrobianas del IBEC.<\/p>\n

—<\/p>\n

Art\u00edculo de referencia:<\/em><\/strong> Estela Noguera-Ortega, N\u00faria Blanco-Cabra, Rosa Maria Rabanal, Alejandro S\u00e1nchez-Chardi, M\u00f3nica Rold\u00e1n, Sandra Guallar-Garrido, Eduard Torrents, Marina Luquin & Esther Juli\u00e1n (2016). \u201cMycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment.\u201d Scientific Reports<\/em>, 6:27232. http:\/\/www.nature.com\/articles\/srep27232<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\"micobacteris\"<\/a>Investigadores de la Universidad Aut\u00f3noma de Barcelona (UAB) y del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) han descubierto una manera efectiva de administrar la micobacteria M. brumae necesaria para el tratamiento de c\u00e1ncer de vejiga en humanos. <\/h3>\n

Los investigadores han encontrado una forma de reducir la formaci\u00f3n de los grumos naturales que se producen cuando se introduce a las micobacterias, que poseen un alto contenido de l\u00edpidos en sus paredes, en las soluciones acuosas que habitualmente se utilizan para la instilaci\u00f3n intravesical <\/p>\n","protected":false},"author":4,"featured_media":23516,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[152,208,207],"post_formats":[],"class_list":["post-23524","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion","tag-ibec-es","tag-m-brumae","tag-micobacteris"],"yoast_head":"\nMicobacterias en aceite de oliva para el tratamiento del c\u00e1ncer - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Micobacterias en aceite de oliva para el tratamiento del c\u00e1ncer - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Investigadores de la Universidad Aut\u00f3noma de Barcelona (UAB) y del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) han descubierto una manera efectiva de administrar la micobacteria M. brumae necesaria para el tratamiento de c\u00e1ncer de vejiga en humanos. Los investigadores han encontrado una forma de reducir la formaci\u00f3n de los grumos naturales que se producen cuando se introduce a las micobacterias, que poseen un alto contenido de l\u00edpidos en sus paredes, en las soluciones acuosas que habitualmente se utilizan para la instilaci\u00f3n intravesical\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2016-06-23T07:46:57+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2016-07-07T10:40:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2016\/06\/micobacterisweb.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"480\" \/>\n\t<meta property=\"og:image:height\" content=\"270\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Micobacterias en aceite de oliva para el tratamiento del c\u00e1ncer\",\"datePublished\":\"2016-06-23T07:46:57+00:00\",\"dateModified\":\"2016-07-07T10:40:48+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\\\/\"},\"wordCount\":365,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2016\\\/06\\\/micobacterisweb.jpg\",\"keywords\":[\"IBEC\",\"M. brumae\",\"Micobacteris\"],\"articleSection\":[\"Noticias de investigaci\u00f3n\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer\\\/\",\"name\":\"Micobacterias en aceite de oliva para el tratamiento del c\u00e1ncer - 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