{"id":30317,"date":"2017-07-05T12:01:33","date_gmt":"2017-07-05T10:01:33","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/es\/?p=30317"},"modified":"2017-07-12T12:29:48","modified_gmt":"2017-07-12T10:29:48","slug":"ibec-destacado-en-el-especial-investigadores-emergentes-de-la-revista-chemcomm","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/ibec-destacado-en-el-especial-investigadores-emergentes-de-la-revista-chemcomm\/","title":{"rendered":"IBEC destacado en el especial \u00abInvestigadores Emergentes\u00bb de la revista ChemComm"},"content":{"rendered":"

El art\u00edculo del grupo de investigaci\u00f3n Nanoscopy for Nanomedicine<\/a> describe una nueva forma de estudiar la estructura y la din\u00e1mica de los sistemas de autoensamblaje de p\u00e9ptidos cortos, que juegan un papel fundamental en nanotecnolog\u00eda y en qu\u00edmica de materiales, debido a sus interesantes propiedades y a la facilidad con la que pueden ser sintetizados.<\/p>\n

\"\"<\/p>\n

Fibras autoensambladas de un peque\u00f1o p\u00e9ptido gener\u00e1ndose de forma controlada. Pueden formar estructuras tubulares tanto grandes y r\u00edgidas como flexibles y m\u00e1s delgadas.<\/h6>\n
<\/div>\n

Los p\u00e9ptidos cortos act\u00faan como bloques de construcci\u00f3n para generar una combinaci\u00f3n de materiales compleja – incluyendo nanopart\u00edculas, nanofibras y nanotubos – que var\u00edan en tama\u00f1o, forma y construcci\u00f3n.<\/p>\n

\u201cEs importante entender la formaci\u00f3n y las propiedades de estas nanoestructuras autoensambladas para poder dirigir su s\u00edntesis y autoorganizaci\u00f3n con aplicaciones espec\u00edficas en mente, como el suministro de f\u00e1rmacos\u00bb, dice Silvia Pujals, postdoc en el grupo Nanoscopy for Nanomedicine<\/em> y primera autora del art\u00edculo. \u00abPero son dif\u00edciles de estudiar debido a su tama\u00f1o y naturaleza din\u00e1mica, y los m\u00e9todos utilizados hasta la fecha no son suficientemente precisos\u00bb.<\/p>\n

Como expertos en microscop\u00eda de super resoluci\u00f3n, tambi\u00e9n conocida como nanoscop\u00eda, el grupo Nanoscopy for Nanomedicine<\/em> del IBEC ha aunado esfuerzos y conocimientos con Ehud Gazit de la Universidad de Tel Aviv (TAU), que tambi\u00e9n est\u00e1 interesado en la estructura molecular y el autoensamblaje a escala nanom\u00e9trica. Juntos, se les ocurri\u00f3 un m\u00e9todo para visualizar las nanoestructuras desde la escala milim\u00e9trica hasta el nivel nanom\u00e9trico usando microscop\u00eda de fluorescencia y nanoscop\u00eda. \u00abEsto nos ha permitido revelar fen\u00f3menos interesantes que antes no se pod\u00edan ver\u00bb, explica Lorenzo. \u00abHemos sido capaces de observar la coexistencia de diferentes topolog\u00edas de ensamblaje y las propiedades de intercambio de mon\u00f3meros, que es informaci\u00f3n crucial para entender el mecanismo subyacente del autoensamblaje bioinspirado\u00bb.<\/p>\n

Gazit, uno de los principales investigadores mundiales en nanotecnolog\u00eda y Jefe Cient\u00edfico del Ministerio de Ciencia y Tecnolog\u00eda de Israel hasta 2014, fue uno de los visitantes del IBEC en mayo de 2015 durante el TAU\/IBEC joint symposium<\/a>, donde este proyecto fue concebido. \u00abDespu\u00e9s de mi charla estuvimos sentados uno al lado del otro y discutimos una posible colaboraci\u00f3n, y \u00e9l me pregunt\u00f3: \u00bfqu\u00e9 marcador fluorescente quieres?\u00bb, recuerda Lorenzo. \u00abEnvi\u00f3 un correo electr\u00f3nico a su postdoc, y antes del final de la charla siguiente, la s\u00edntesis de la mol\u00e9cula que usamos ya estaba produci\u00e9ndose\u00bb.<\/p>\n

—<\/p>\n

Art\u00edculo de referencia:<\/strong><\/em>
\nSilvia Pujals, Kai Tao, Adri\u00e0 Terradellas, Ehud Gazit and Lorenzo Albertazzi (2017). Studying structure and dynamics of self-assembled peptide nanostructures using fluorescence and super resolution microscopy.<\/a> Chemical Communications<\/em>, 2017,\u00a053<\/strong>, 7294-7297<\/p>\n

Este trabajo ha sido financiado a trav\u00e9s del proyecto MINECO \/ FEDER SAF2016-75241-R y del Fondo de Investigaci\u00f3n AXA.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

El investigador principal junior del IBEC, Lorenzo Albertazzi, colabora en la edici\u00f3n de 2017 de ChemComm Emerging Investigators<\/em>, publicada por la Royal Society of Chemistry del Reino Unido.<\/h3>\n

Coincidiendo con su s\u00e9ptimo a\u00f1o, el n\u00famero especial<\/a> muestra las investigaciones llevadas a cabo por cient\u00edficos de reconocido prestigio internacional en las primeras etapas de su carrera y que est\u00e1n sobresaliendo en sus campos.<\/p>\n","protected":false},"author":4,"featured_media":30295,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[],"post_formats":[],"class_list":["post-30317","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion"],"yoast_head":"\nIBEC destacado en el especial "Investigadores Emergentes" de la revista ChemComm - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/ibec-destacado-en-el-especial-investigadores-emergentes-de-la-revista-chemcomm\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IBEC destacado en el especial "Investigadores Emergentes" de la revista ChemComm - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"El investigador principal junior del IBEC, Lorenzo Albertazzi, colabora en la edici\u00f3n de 2017 de ChemComm Emerging Investigators, publicada por la Royal Society of Chemistry del Reino Unido. 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