{"id":57341,"date":"2018-01-19T14:23:51","date_gmt":"2018-01-19T13:23:51","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=57341"},"modified":"2018-02-02T13:07:27","modified_gmt":"2018-02-02T12:07:27","slug":"un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\/","title":{"rendered":"Un nuevo material promueve la generaci\u00f3n de nuevos vasos sangu\u00edneos"},"content":{"rendered":"

Aunque las hMSC pueden promover la neovascularizaci\u00f3n por s\u00ed mismas, cuando se depositan en un tejido su tasa de supervivencia es muy baja. Sin embargo, al encapsularlas en un hidrogel de polietilenglicol biodegradable, su viabilidad se mantiene constante a lo largo del tiempo. <\/p>\n

Imagen: C\u00e9lulas madre mesenquimales humanas formando redes dentro de un hidrogel de polietilenglicol funcionalizado que contiene part\u00edculas de fosfato de calcio.<\/h6>\n

 
\n 
\n 
\n 
\n <\/p>\n

Al mismo tiempo, las part\u00edculas vitrocer\u00e1micas proporcionan la cantidad correcta y sostenida de calcio necesaria para estimular la angiog\u00e9nesis, el proceso a trav\u00e9s del cual se forman nuevos vasos sangu\u00edneos a partir de vasos preexistentes.<\/p>\n

\u00abEsta combinaci\u00f3n de hMSCs y part\u00edculas liberadoras de calcio representa una nueva forma de lograr el crecimiento estable de vasos sangu\u00edneos, que es un factor clave en la regeneraci\u00f3n de los tejidos del cuerpo\u00bb, dice Claudia Navarro, primera autora del estudio y estudiante de doctorado en el grupo del IBEC. \u00abEste estudio podr\u00eda inspirar nuevos tratamientos para trastornos como la arteriopat\u00eda perif\u00e9rica, el infarto de miocardio o las heridas cr\u00f3nicas, todos los cuales presentan un suministro sangu\u00edneo restringido al tejido que dificulta su reparaci\u00f3n y promueve su degeneraci\u00f3n\u00bb.<\/p>\n

—<\/p>\n

Art\u00edculo de referencia<\/a>: Navarro-Requena, C, Weaver, JD, Clark, AY, Clift, DA, P\u00e9rez-Amodio, S, Casta\u00f1o, \u00d3, Zhou, DW, Garc\u00eda, AJ, & Engel, E. (2017). PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation. Acta Biomater. S1742-7061 (17) 30765-1<\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"<\/a>En su esfuerzo para conseguir biomateriales funcionales para la regeneraci\u00f3n de tejidos, el grupo de IBEC Biomaterials for Regenerative Therapies ha dise\u00f1ado un nuevo material que promueve la formaci\u00f3n y maduraci\u00f3n de vasos sangu\u00edneos in vivo. <\/h3>\n

En el art\u00edculo, publicado en Acta Biomaterialia a finales del a\u00f1o pasado, el grupo y sus colaboradores del Georgia Institute of Technology presentan un nuevo hidrogel implantable que contiene c\u00e9lulas madre mesenquimales humanas (hMSC, del ingl\u00e9s human mesenchymal stromal cells) y micropart\u00edculas liberadoras de calcio.<\/p>\n","protected":false},"author":4,"featured_media":57317,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[774],"post_formats":[],"class_list":["post-57341","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion","tag-elisabeth-engel-es"],"yoast_head":"\nUn nuevo material promueve la generaci\u00f3n de nuevos vasos sangu\u00edneos - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un nuevo material promueve la generaci\u00f3n de nuevos vasos sangu\u00edneos - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"En su esfuerzo para conseguir biomateriales funcionales para la regeneraci\u00f3n de tejidos, el grupo de IBEC Biomaterials for Regenerative Therapies ha dise\u00f1ado un nuevo material que promueve la formaci\u00f3n y maduraci\u00f3n de vasos sangu\u00edneos in vivo. En el art\u00edculo, publicado en Acta Biomaterialia a finales del a\u00f1o pasado, el grupo y sus colaboradores del Georgia Institute of Technology presentan un nuevo hidrogel implantable que contiene c\u00e9lulas madre mesenquimales humanas (hMSC, del ingl\u00e9s human mesenchymal stromal cells) y micropart\u00edculas liberadoras de calcio.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2018-01-19T13:23:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-02-02T12:07:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/01\/OscarClaudia_ActaBiom_NdP.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"450\" \/>\n\t<meta property=\"og:image:height\" content=\"449\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Un nuevo material promueve la generaci\u00f3n de nuevos vasos sangu\u00edneos\",\"datePublished\":\"2018-01-19T13:23:51+00:00\",\"dateModified\":\"2018-02-02T12:07:27+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\\\/\"},\"wordCount\":266,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2018\\\/01\\\/OscarClaudia_ActaBiom_NdP.jpg\",\"keywords\":[\"Elisabeth Engel\"],\"articleSection\":[\"Noticias de investigaci\u00f3n\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-nuevo-material-promueve-la-generacion-de-nuevos-vasos-sanguineos\\\/\",\"name\":\"Un nuevo material promueve la generaci\u00f3n de nuevos vasos sangu\u00edneos - 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