{"id":61374,"date":"2018-09-12T13:47:00","date_gmt":"2018-09-12T11:47:00","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=61374"},"modified":"2018-09-13T12:11:09","modified_gmt":"2018-09-13T10:11:09","slug":"la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\/","title":{"rendered":"La apnea del sue\u00f1o podr\u00eda promover el crecimiento tumoral en los j\u00f3venes"},"content":{"rendered":"<p>Los investigadores, incluido el grupo del IBEC <a href=\"https:\/\/ibecbarcelona.eu\/cellmech\" target=\"_blank\" rel=\"noopener\">Cellular and respiratory biomechanics<\/a> (en la imagen) &#8211; dirigido por Daniel Navajas -, llevaron a cabo su estudio en ratones j\u00f3venes, equivalentes a adolescentes humanos, as\u00ed como en ratones de edad avanzada &#8211; que corresponden a personas mayores de 65 a\u00f1os. Encontraron que la falta de ox\u00edgeno durante la apnea del sue\u00f1o (hipoxia) &#8211; una enfermedad cr\u00f3nica que afecta aproximadamente el 10% de la poblaci\u00f3n adulta en todo el mundo &#8211; aceler\u00f3 el crecimiento tumoral solo en los m\u00e1s j\u00f3venes.<\/p>\n<p>El equipo de investigaci\u00f3n relacion\u00f3 estos resultados con una respuesta inmune diferencial a la hipoxia intermitente en los macr\u00f3fagos asociados con el tumor y en los linfocitos reguladores. \u00abNuestro desaf\u00edo ahora es identificar y probar las consecuencias fisiopatol\u00f3gicas de la apnea del sue\u00f1o y contribuir al desarrollo de la medicina personalizada para trabajar en su manejo\u00bb, dice Isaac Almendros, profesor adjunto de la Facultad de Medicina y Ciencias de la Salud de la UB e IDIBAPS.<\/p>\n<p>La investigaci\u00f3n, liderada por Ram\u00f3n Farr\u00e9 de la UB, Josep Mar\u00eda Montserrat e Isaac Almendros, representa un avance cient\u00edfico importante en la comprensi\u00f3n de los posibles efectos de la apnea obstructiva del sue\u00f1o en el c\u00e1ncer. El equipo de investigaci\u00f3n ya fue pionero en el campo con su contribuci\u00f3n de la primera evidencia del papel de la hipoxia intermitente en el desarrollo del c\u00e1ncer.<\/p>\n<p>Otros participantes en el estudio fueron de la Universidad La Fe y el Hospital T\u00e9cnico de Valencia, el Hospital Virgen de Valme en Sevilla y la Universidad de Chicago, entre otras instituciones. La investigaci\u00f3n se llev\u00f3 a cabo dentro del Centro de Investigaci\u00f3n Biom\u00e9dica de Redes de Enfermedades Respiratorias (<a href=\"http:\/\/www.ciberes.org\/es\" target=\"_blank\" rel=\"noopener\">CIBERES<\/a>), un \u00e1rea de investigaci\u00f3n del consorcio p\u00fablico de investigaci\u00f3n Consorcio Centro de Investigaci\u00f3n Biom\u00e9dica en Red (<a href=\"https:\/\/www.ciberisciii.es\/es\" target=\"_blank\" rel=\"noopener\">CIBER<\/a>), creado en 2006 para promover la investigaci\u00f3n en biomedicina y ciencias de la salud.<\/p>\n<p>&#8212;<\/p>\n<p>Torres, M., Campillo, N., Nonaka, P.N., Montserrat, J.M., Gozal, D., Mart\u00ednez-Garc\u00eda, M.A., Campos-Rodriguez, F., Navajas, D., Farr\u00e9, R., Almendros, I. (2018). \u201c<a href=\"https:\/\/www.atsjournals.org\/doi\/abs\/10.1164\/rccm.201805-0892LE?journalCode=ajrccm\" target=\"_blank\" rel=\"noopener\">Aging Reduces Intermittent Hypoxia-induced Lung Carcinoma Growth in a Mouse Model of Sleep Apnea<\/a>\u201d. <em>Am J Respir Crit Care Med.<\/em>, epub ahead of print<\/p>\n","protected":false},"excerpt":{"rendered":"<h3><img decoding=\"async\" data-src=\"http:\/\/www.ibecbarcelona.eu\/wp-content\/uploads\/2018\/09\/Navajas_UB.jpg\" alt=\"\" width=\"450\" height=\"276\" class=\"left size-full wp-image-61344 lazyload\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/09\/Navajas_UB.jpg 450w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/09\/Navajas_UB-300x184.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/09\/Navajas_UB-212x130.jpg 212w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/09\/Navajas_UB-150x92.jpg 150w\" data-sizes=\"(max-width: 450px) 100vw, 450px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 450px; --smush-placeholder-aspect-ratio: 450\/276;\" \/>Un estudio publicado en el American Journal of Respiratory and Critical Care Medicine ha revelado que la apnea del sue\u00f1o podr\u00eda promover el crecimiento del c\u00e1ncer de pulm\u00f3n en individuos j\u00f3venes. <\/h3>\n<p>Investigadores del IBEC, la Universidad de Barcelona y el Hospital Cl\u00ednic muestran que, contrariamente a lo esperado, la edad puede ser un factor de protecci\u00f3n contra el r\u00e1pido desarrollo tumoral inducido por esta alteraci\u00f3n respiratoria del sue\u00f1o y su consecuencia inmediata, la hipoxia intermitente.<\/p>\n","protected":false},"author":4,"featured_media":61346,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[754],"post_formats":[],"class_list":["post-61374","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion","tag-daniel-navajas-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>La apnea del sue\u00f1o podr\u00eda promover el crecimiento tumoral en los j\u00f3venes - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La apnea del sue\u00f1o podr\u00eda promover el crecimiento tumoral en los j\u00f3venes - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Un estudio publicado en el American Journal of Respiratory and Critical Care Medicine ha revelado que la apnea del sue\u00f1o podr\u00eda promover el crecimiento del c\u00e1ncer de pulm\u00f3n en individuos j\u00f3venes.   Investigadores del IBEC, la Universidad de Barcelona y el Hospital Cl\u00ednic muestran que, contrariamente a lo esperado, la edad puede ser un factor de protecci\u00f3n contra el r\u00e1pido desarrollo tumoral inducido por esta alteraci\u00f3n respiratoria del sue\u00f1o y su consecuencia inmediata, la hipoxia intermitente.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2018-09-12T11:47:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-09-13T10:11:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/09\/Navajas_UB.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"450\" \/>\n\t<meta property=\"og:image:height\" content=\"276\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"La apnea del sue\u00f1o podr\u00eda promover el crecimiento tumoral en los j\u00f3venes\",\"datePublished\":\"2018-09-12T11:47:00+00:00\",\"dateModified\":\"2018-09-13T10:11:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\\\/\"},\"wordCount\":403,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2018\\\/09\\\/Navajas_UB.jpg\",\"keywords\":[\"Daniel Navajas\"],\"articleSection\":[\"Noticias de investigaci\u00f3n\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/la-apnea-del-sueno-podria-promover-el-crecimiento-tumoral-en-los-jovenes\\\/\",\"name\":\"La apnea del sue\u00f1o podr\u00eda promover el crecimiento tumoral en los j\u00f3venes - 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