{"id":68033,"date":"2019-08-09T09:24:08","date_gmt":"2019-08-09T07:24:08","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=68033"},"modified":"2019-08-30T12:52:11","modified_gmt":"2019-08-30T10:52:11","slug":"los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/","title":{"rendered":"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria"},"content":{"rendered":"<p>Para superar este obst\u00e1culo, el equipo de Fern\u00e1ndez-Busquets ha desarrollado un nanovector \u2013que consiste en peque\u00f1as esferas o liposomas\u2013 capaz de\u00a0<strong>transportar simult\u00e1neamente mol\u00e9culas solubles en agua<\/strong>\u00a0(hidrof\u00edlicos)\u00a0<strong>y en l\u00edpidos<\/strong>\u00a0(lipof\u00edlicos).<\/p>\n<p>\u201cAl encapsular los dos f\u00e1rmacos en el mismo nanovector, nos aseguramos de que ambos perdurar\u00e1n el mismo tiempo en el organismo,\u201d explica Fern\u00e1ndez-Busquets. Como prueba de concepto, el equipo investigador introdujo el f\u00e1rmaco hidrosoluble pironaridina en la cavidad interna del liposoma, y el f\u00e1rmaco liposoluble atovacuona en la membrana del mismo. Adem\u00e1s, rodearon el liposoma de un anticuerpo que reconoce una prote\u00edna expresada por gl\u00f3bulos rojos (que est\u00e9n infectados o no) y gametocitos (la fase sexual del par\u00e1sito responsable de la transmisi\u00f3n entre hu\u00e9spedes). De ah\u00ed el nombre de inmunoliposoma.<\/p>\n<p>Los resultados muestran que ambos f\u00e1rmacos, cuando encapsulados, fueron capaces de\u00a0<strong>inhibir el crecimiento del par\u00e1sito\u00a0<\/strong><em>in vitro<\/em>\u00a0a concentraciones que no ten\u00edan ning\u00fan efecto cuando estaban libres. Gracias a los anticuerpos, los inmunoliposomas\u00a0<strong>se unieron r\u00e1pidamente a la c\u00e9lula diana y administraron el f\u00e1rmaco\u00a0<\/strong>de manera muy eficiente.<\/p>\n<p>Los autores se\u00f1alan que esta estrategia podr\u00eda aplicarse en un futuro cercano a casos de malaria grave que ingresan al hospital, donde la administraci\u00f3n intravenosa de liposomas es factible. El reto ser\u00e1 desarrollar nanovectores de administraci\u00f3n oral para tratar la malaria no grave, l\u00ednea de trabajo que el mismo grupo de investigaci\u00f3n tambi\u00e9n est\u00e1 explorando.<\/p>\n<p>\u201cLos tratamientos actuales act\u00faan mayoritariamente sobre las fases asexuales del par\u00e1sito. Esta nueva estrategia actuar\u00eda tambi\u00e9n sobre la fase sexual o gametocito, la \u00fanica fase del par\u00e1sito que se puede transmitir de humanos a mosquitos, y ayudar\u00eda a reducir la emergencia y propagaci\u00f3n de resistencias,\u201d a\u00f1ade el investigador.<\/p>\n<p><strong>Art\u00edculo de referencia: <\/strong>Biosca A, Dirscherl L, Moles E, Imperial S, Fern\u00e0ndez-Busquets X. An ImmunoPEGliposome for Targeted Antimalarial Combination Therapy at the Nanoscale. Pharmaceutics. 2019 Jul 16;11(7). pii: E341.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31315185\" target=\"_blank\" rel=\"noopener noreferrer\">doi: 10.3390\/pharmaceutics11070341<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<h3><img decoding=\"async\" class=\"alignnone wp-image-68028 size-medium lazyload\" data-src=\"http:\/\/www.ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-300x142.jpg\" alt=\"Nanovector_IBEC\" width=\"300\" height=\"142\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-300x142.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-768x363.jpg 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-1024x484.jpg 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-230x109.jpg 230w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-150x71.jpg 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg 1600w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/142;\" \/>Seg\u00fan indica el estudio, la estrategia tiene adem\u00e1s la ventaja de reconocer al gametocito, la fase transmisible del par\u00e1sito. Encapsular dos f\u00e1rmacos con propiedades diferentes en nanoves\u00edculas rodeadas por anticuerpos mejora notablemente la especificidad y eficacia de los mismos, seg\u00fan un estudio liderado por Xavier Fern\u00e1ndez-Busquets, director de la unidad mixta de Nanomalaria del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Instituto de Salud Global de Barcelona (ISGlobal), centro impulsado por \u201dla Caixa\u201d.<\/h3>\n<\/p>\n<p>La combinaci\u00f3n de dos f\u00e1rmacos que difieren en su mecanismo de acci\u00f3n es la base de las terapias m\u00e1s exitosas hoy en d\u00eda para tratar la malaria. Sin embargo, la diferencia en propiedades fisicoqu\u00edmicas de los f\u00e1rmacos (solubilidad, vida media, etc.) afecta muchas veces a la eficacia del tratamiento.<\/p>\n","protected":false},"author":4,"featured_media":68029,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[315,151,1111],"post_formats":[],"class_list":["post-68033","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion","tag-malaria-es-2","tag-malaria-es","tag-xavier-fernandez-busquets-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Seg\u00fan indica el estudio, la estrategia tiene adem\u00e1s la ventaja de reconocer al gametocito, la fase transmisible del par\u00e1sito. Encapsular dos f\u00e1rmacos con propiedades diferentes en nanoves\u00edculas rodeadas por anticuerpos mejora notablemente la especificidad y eficacia de los mismos, seg\u00fan un estudio liderado por Xavier Fern\u00e1ndez-Busquets, director de la unidad mixta de Nanomalaria del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Instituto de Salud Global de Barcelona (ISGlobal), centro impulsado por \u201dla Caixa\u201d.  La combinaci\u00f3n de dos f\u00e1rmacos que difieren en su mecanismo de acci\u00f3n es la base de las terapias m\u00e1s exitosas hoy en d\u00eda para tratar la malaria. Sin embargo, la diferencia en propiedades fisicoqu\u00edmicas de los f\u00e1rmacos (solubilidad, vida media, etc.) afecta muchas veces a la eficacia del tratamiento.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2019-08-09T07:24:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-08-30T10:52:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1600\" \/>\n\t<meta property=\"og:image:height\" content=\"756\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria\",\"datePublished\":\"2019-08-09T07:24:08+00:00\",\"dateModified\":\"2019-08-30T10:52:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/\"},\"wordCount\":362,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2019\\\/08\\\/Nanovectors-malaria.jpg\",\"keywords\":[\"malaria\",\"malaria\",\"Xavier Fernandez-Busquets\"],\"articleSection\":[\"Noticias de investigaci\u00f3n\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/\",\"name\":\"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria - Institute for Bioengineering of Catalonia\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2019\\\/08\\\/Nanovectors-malaria.jpg\",\"datePublished\":\"2019-08-09T07:24:08+00:00\",\"dateModified\":\"2019-08-30T10:52:11+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2019\\\/08\\\/Nanovectors-malaria.jpg\",\"contentUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2019\\\/08\\\/Nanovectors-malaria.jpg\",\"width\":1600,\"height\":756,\"caption\":\"Nanovector_IBEC\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#website\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/\",\"name\":\"Institute for Bioengineering of Catalonia\",\"description\":\"Bioengineering solutions for health\",\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ibecbarcelona.eu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\",\"name\":\"Institute for Bioengineering of Catalonia\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/cropped-IBEC_20ANYS_GRIS.png\",\"contentUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/cropped-IBEC_20ANYS_GRIS.png\",\"width\":696,\"height\":257,\"caption\":\"Institute for Bioengineering of Catalonia\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\",\"name\":\"\u00c0ngels L\u00f3pez\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g\",\"caption\":\"\u00c0ngels L\u00f3pez\"},\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/author\\\/alopez\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria - Institute for Bioengineering of Catalonia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/","og_locale":"es_ES","og_type":"article","og_title":"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria - Institute for Bioengineering of Catalonia","og_description":"Seg\u00fan indica el estudio, la estrategia tiene adem\u00e1s la ventaja de reconocer al gametocito, la fase transmisible del par\u00e1sito. Encapsular dos f\u00e1rmacos con propiedades diferentes en nanoves\u00edculas rodeadas por anticuerpos mejora notablemente la especificidad y eficacia de los mismos, seg\u00fan un estudio liderado por Xavier Fern\u00e1ndez-Busquets, director de la unidad mixta de Nanomalaria del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Instituto de Salud Global de Barcelona (ISGlobal), centro impulsado por \u201dla Caixa\u201d.  La combinaci\u00f3n de dos f\u00e1rmacos que difieren en su mecanismo de acci\u00f3n es la base de las terapias m\u00e1s exitosas hoy en d\u00eda para tratar la malaria. Sin embargo, la diferencia en propiedades fisicoqu\u00edmicas de los f\u00e1rmacos (solubilidad, vida media, etc.) afecta muchas veces a la eficacia del tratamiento.","og_url":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/","og_site_name":"Institute for Bioengineering of Catalonia","article_published_time":"2019-08-09T07:24:08+00:00","article_modified_time":"2019-08-30T10:52:11+00:00","og_image":[{"width":1600,"height":756,"url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg","type":"image\/jpeg"}],"author":"\u00c0ngels L\u00f3pez","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"\u00c0ngels L\u00f3pez","Tiempo de lectura":"2 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#article","isPartOf":{"@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/"},"author":{"name":"\u00c0ngels L\u00f3pez","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/person\/c212c6b589546130be67986b9290e2b8"},"headline":"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria","datePublished":"2019-08-09T07:24:08+00:00","dateModified":"2019-08-30T10:52:11+00:00","mainEntityOfPage":{"@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/"},"wordCount":362,"publisher":{"@id":"https:\/\/ibecbarcelona.eu\/#organization"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#primaryimage"},"thumbnailUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg","keywords":["malaria","malaria","Xavier Fernandez-Busquets"],"articleSection":["Noticias de investigaci\u00f3n"],"inLanguage":"es"},{"@type":"WebPage","@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/","url":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/","name":"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria - Institute for Bioengineering of Catalonia","isPartOf":{"@id":"https:\/\/ibecbarcelona.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#primaryimage"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#primaryimage"},"thumbnailUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg","datePublished":"2019-08-09T07:24:08+00:00","dateModified":"2019-08-30T10:52:11+00:00","breadcrumb":{"@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#primaryimage","url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg","contentUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg","width":1600,"height":756,"caption":"Nanovector_IBEC"},{"@type":"BreadcrumbList","@id":"https:\/\/ibecbarcelona.eu\/es\/los-nanovectores-podrian-mejorar-la-administracion-combinada-de-farmacos-contra-la-malaria\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ibecbarcelona.eu\/es\/"},{"@type":"ListItem","position":2,"name":"Los nanovectores podr\u00edan mejorar la administraci\u00f3n combinada de f\u00e1rmacos contra la malaria"}]},{"@type":"WebSite","@id":"https:\/\/ibecbarcelona.eu\/#website","url":"https:\/\/ibecbarcelona.eu\/","name":"Institute for Bioengineering of Catalonia","description":"Bioengineering solutions for health","publisher":{"@id":"https:\/\/ibecbarcelona.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ibecbarcelona.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/ibecbarcelona.eu\/#organization","name":"Institute for Bioengineering of Catalonia","url":"https:\/\/ibecbarcelona.eu\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/logo\/image\/","url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/01\/cropped-IBEC_20ANYS_GRIS.png","contentUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/01\/cropped-IBEC_20ANYS_GRIS.png","width":696,"height":257,"caption":"Institute for Bioengineering of Catalonia"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/person\/c212c6b589546130be67986b9290e2b8","name":"\u00c0ngels L\u00f3pez","image":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/secure.gravatar.com\/avatar\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g","caption":"\u00c0ngels L\u00f3pez"},"url":"https:\/\/ibecbarcelona.eu\/es\/author\/alopez\/"}]}},"AFP_featured_media_urls":{"full":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg",1600,756,false],"thumbnail":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-150x150.jpg",150,150,true],"medium":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-300x142.jpg",300,142,true],"medium_large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-768x363.jpg",768,363,true],"large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-1024x484.jpg",1024,484,true]},"AFP_attachments":{"full":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria.jpg",1600,756,false],"thumbnail":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-150x150.jpg",150,150,true],"medium":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-300x142.jpg",300,142,true],"medium_large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-768x363.jpg",768,363,true],"large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2019\/08\/Nanovectors-malaria-1024x484.jpg",1024,484,true]},"AFP_videos":[],"AFP_video_blocks":"","AFP_category_names":["Noticias de investigaci\u00f3n"],"_links":{"self":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts\/68033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/comments?post=68033"}],"version-history":[{"count":1,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts\/68033\/revisions"}],"predecessor-version":[{"id":68034,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/posts\/68033\/revisions\/68034"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/media\/68029"}],"wp:attachment":[{"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/media?parent=68033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/categories?post=68033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/tags?post=68033"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/es\/wp-json\/wp\/v2\/post_formats?post=68033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}