{"id":72940,"date":"2020-03-27T13:18:54","date_gmt":"2020-03-27T12:18:54","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=72940"},"modified":"2020-06-09T15:22:55","modified_gmt":"2020-06-09T13:22:55","slug":"un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\/","title":{"rendered":"Un investigador del IBEC desarrolla un modelo para la nanomedicina de precisi\u00f3n"},"content":{"rendered":"

Tras probar cientos de productos qu\u00edmicos, e<\/span>l m\u00e9dico y bacteri\u00f3logo alem\u00e1n Paul Ehrlich<\/span>,\u00a0<\/span>ganador del premio Nobel de Medicina en 1908<\/span>,<\/span>\u00a0<\/span>descubri\u00f3 un compuesto que pod\u00eda matar de forma selectiva a las bacterias de la especie\u00a0<\/span>Treponema\u00a0<\/span><\/i>pallidum<\/span><\/i>,<\/span>\u00a0las causantes de la s\u00edfilis.\u00a0<\/span>\u00a0<\/span><\/p>\n

El\u00a0<\/span>experto<\/span>\u00a0sigui\u00f3\u00a0<\/span>investigando<\/span>\u00a0en esta misma l\u00ednea durante los a\u00f1os que vinieron<\/span>\u00a0<\/span>con el objetivo de\u00a0<\/span>descubrir m\u00e1s<\/span>\u00a0<\/span>\u201cbalas m\u00e1gicas\u201d capaces de atacar a los pat\u00f3genos invasores sin causar da\u00f1o<\/span>s<\/span>\u00a0en las c\u00e9lulas del hu\u00e9sped.\u00a0<\/span>No lo sab\u00eda, pero estaba sentando las bases de las\u00a0<\/span>bases de la farmacolog\u00eda<\/span>. De hecho, s<\/span>u<\/span>\u00a0idea de que existen agentes terap\u00e9uticos \u201cideales\u201d que act\u00faan de forma espec\u00edfica contra los\u00a0<\/span>agentes infecciosos\u00a0<\/span>sigue siendo v\u00e1lida hoy en d\u00eda.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

Ahora<\/span>, un grupo de investigadores del Instituto de Bioingenier\u00eda de Catalunya (IBEC) liderados por Giuseppe\u00a0<\/span>Battaglia<\/span>,\u00a0<\/span>investigador principal en el grupo de Bi\u00f3nica\u00a0Molecuar<\/span>\u00a0del IBEC<\/span>,<\/span>\u00a0ha desarrollado un modelo\u00a0<\/span>p<\/span>ara la medicina de precisi\u00f3n basado tambi\u00e9n en esta idea de \u201cselectividad\u201d<\/span>\u00a0que defend\u00eda\u00a0<\/span>Ehrlich<\/span>.<\/span>\u00a0<\/span><\/p>\n

En su trabajo, publicado recientemente en la revista especializada\u00a0Science\u00a0Advances<\/a>, los autores relatan que lo que hace que las nanopart\u00edculas se adhieran a\u00a0<\/span>otras part\u00edculas<\/span>\u00a0son las caracter\u00edsticas de la corona de vellosidades que las recubre.\u00a0<\/span>\u00a0<\/span><\/p>\n

Por ello, el modelo que proponen los investigadores tiene en cuenta tanto el tama\u00f1o<\/span>\u00a0de las nanopart\u00edculas<\/span>\u00a0como la largada y el n\u00famero de vellosidades\u00a0<\/span>que las recubren<\/span>.\u00a0<\/span>Asimismo, los expertos a\u00f1aden al modelo un t\u00e9rmino adicional, la \u201cafinidad\u201d<\/span>, que<\/span>\u00a0juntamente con los otros tres<\/span>,<\/span>\u00a0<\/span>permite la \u201csuperselectividad\u201d de las nanopart\u00edculas<\/span>.<\/span>\u00a0<\/span><\/p>\n

Seg\u00fan los expertos, el modelo permite\u00a0<\/span>dise\u00f1ar nanopart\u00edculas a medida para cada paciente, lo que puede ser de gran ayuda para\u00a0<\/span>personalizar las terapias<\/span>.<\/span>\u00a0Adem\u00e1s, el modelo aporta algunas de las claves para entender c\u00f3mo interaccionan\u00a0<\/span>en los sistemas biol\u00f3gicos<\/span>\u00a0<\/span>las c\u00e9lulas, los virus, las bacterias o las prote\u00ednas entre ellas<\/span>.<\/span>\u00a0<\/span><\/p>\n

 <\/p>\n

Art\u00edculo de referencia:<\/strong> X.\u00a0<\/span>Tian<\/span>, S.\u00a0<\/span>Ang<\/span>ioletti-Uberti<\/span>\u00a0and G.\u00a0<\/span>Battaglia<\/span>\u00a0(2020).\u00a0<\/span>On the design of precision\u00a0<\/span>nanomedicines<\/span>.<\/span>\u00a0<\/span>Science\u00a0<\/span><\/i>Advances<\/span><\/i><\/a>, volume 6, issue 4.<\/span> DOI: 10.1126\/sciadv.aat0919<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"Investigadores del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) han propuesto un modelo que ofrece informaci\u00f3n importante sobre c\u00f3mo las nanopart\u00edculas interact\u00faan con c\u00e9lulas, virus, bacterias o prote\u00ednas, entre otros.<\/h3>\n

El modelo tiene en cuenta los distintos factores que determinan la afinidad de las nanopart\u00edculas con c\u00e9lulas, virus, bacterias o prote\u00ednas, lo que es clave para elaborar f\u00e1rmacos a medida para cada paciente. <\/p>\n","protected":false},"author":4,"featured_media":72935,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[97],"tags":[1106,249,914],"post_formats":[],"class_list":["post-72940","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-de-investigacion","tag-giuseppe-battaglia-es","tag-nanomedicina","tag-nanoparticulas"],"yoast_head":"\nUn investigador del IBEC desarrolla un modelo para la nanomedicina de precisi\u00f3n - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un investigador del IBEC desarrolla un modelo para la nanomedicina de precisi\u00f3n - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Investigadores del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) han propuesto un modelo que ofrece informaci\u00f3n importante sobre c\u00f3mo las nanopart\u00edculas interact\u00faan con c\u00e9lulas, virus, bacterias o prote\u00ednas, entre otros. El modelo tiene en cuenta los distintos factores que determinan la afinidad de las nanopart\u00edculas con c\u00e9lulas, virus, bacterias o prote\u00ednas, lo que es clave para elaborar f\u00e1rmacos a medida para cada paciente.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2020-03-27T12:18:54+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-06-09T13:22:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/03\/GBattaglia.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"333\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Un investigador del IBEC desarrolla un modelo para la nanomedicina de precisi\u00f3n\",\"datePublished\":\"2020-03-27T12:18:54+00:00\",\"dateModified\":\"2020-06-09T13:22:55+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\\\/\"},\"wordCount\":387,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2020\\\/03\\\/GBattaglia.jpg\",\"keywords\":[\"Giuseppe Battaglia\",\"nanomedicina\",\"Nanopart\u00edculas\"],\"articleSection\":[\"Noticias de investigaci\u00f3n\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-investigador-del-ibec-desarrolla-un-modelo-para-la-nanomedicina-de-precision\\\/\",\"name\":\"Un investigador del IBEC desarrolla un modelo para la nanomedicina de precisi\u00f3n - 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