{"id":73002,"date":"2020-03-31T12:03:09","date_gmt":"2020-03-31T10:03:09","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=73002"},"modified":"2020-06-15T13:13:50","modified_gmt":"2020-06-15T11:13:50","slug":"el-investigador-xavier-trepat-recibe-2-5-m-de-la-ue-para-crear-las-bases-de-una-nueva-generacion-de-robots-biologicos","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/el-investigador-xavier-trepat-recibe-2-5-m-de-la-ue-para-crear-las-bases-de-una-nueva-generacion-de-robots-biologicos\/","title":{"rendered":"El investigador Xavier Trepat recibe la ERC Advanced Grant para crear las bases de una nueva generaci\u00f3n de robots biol\u00f3gicos"},"content":{"rendered":"

E<\/span>l Consejo Europeo de Investigaci\u00f3n (ERC<\/span>,<\/span>\u00a0por sus siglas en\u00a0<\/span>ingl\u00e9s<\/span>)<\/span>\u2014<\/span>una organizaci\u00f3n p\u00fablica europea que financia proyectos de\u00a0<\/span>investigaci\u00f3n<\/span>\u2014<\/span>ha otorgado a Xavier\u00a0<\/span>Trepat<\/span>, profesor ICREA\u00a0<\/span>e investigador principal en el<\/span>\u00a0<\/span>Instituto de Bioingenier\u00eda de Catalunya (<\/span>IBEC<\/span>)<\/span>,\u00a0<\/span>la<\/span>\u00a0prestigiosa beca<\/span>\u00a0ERC\u00a0<\/span>Advanced<\/span>\u00a0Grant<\/span>, dotada con<\/span>\u00a02,5\u00a0<\/span>M<\/span>\u00a0de<\/span>\u00a0e<\/span>uros<\/span>.<\/span>\u00a0Antes de\u00a0<\/span>conseguir\u00a0<\/span>esta beca, el investigador\u00a0<\/span>tambi\u00e9n\u00a0<\/span>obtuvo\u00a0<\/span>las subvenciones<\/span>\u00a0<\/span>\u201c<\/span>Starting<\/span>\u00a0<\/span>G<\/span>rant\u201d<\/span>,<\/span>\u00a0\u201c<\/span>Consolidator<\/span>\u00a0<\/span>G<\/span>rant<\/span>\u201d y \u201c<\/span>Proof<\/span>\u00a0<\/span>of<\/span>\u00a0Concept\u201d<\/span>,<\/span>\u00a0todas ellas otorgadas por la ERC<\/span>.\u00a0<\/span>\u00a0<\/span><\/p>\n

Gracias a este reconocimiento,\u00a0<\/span>el experto\u00a0<\/span>podr\u00e1 desarrollar durante<\/span>\u00a0cinco a\u00f1os<\/span>\u00a0el proyecto \u201c<\/span>EpiFold<\/span>\u201d<\/span>,<\/span>\u00a0que se centrar\u00e1<\/span>\u00a0en la comprensi\u00f3n de los principios y las propiedades mec\u00e1nicas d<\/span>el epitelio en<\/span>\u00a03D<\/span>.\u00a0<\/span>Asimismo,\u00a0<\/span>Trepat<\/span>\u00a0y su equipo<\/span>\u00a0<\/span>ir\u00e1n<\/span>\u00a0un paso m\u00e1s all\u00e1<\/span>\u00a0y desarrolla<\/span>r\u00e1n<\/span>\u00a0una nueva tecnolog\u00eda para\u00a0<\/span>sentar las bases de\u00a0<\/span>una nueva generaci\u00f3n de dispositivos\u00a0<\/span>bioh\u00edbridos<\/span>\u00a0<\/span>que tendr\u00edan<\/span>\u00a0<\/span>una capacidad \u00fanica<\/span>\u00a0<\/span>para potenciar funciones en robots b<\/span>iol\u00f3gicos<\/span>.<\/span>\u00a0<\/span><\/p>\n

Todas las superficies de nuestro cuerpo, tanto internas como externas, est\u00e1n cubiertas por delgadas capas celulares ll<\/span>amadas epitelio<\/span>. El tejido epitelial desempe\u00f1a un papel crucial en las funciones fisiol\u00f3gicas humanas fundamentales, como<\/span>\u00a0lo son<\/span>\u00a0la morfog\u00e9nesis, la filtraci\u00f3n, el transporte o<\/span>\u00a0<\/span>la protecci\u00f3n\u00a0<\/span>ante pat\u00f3genos.<\/span>\u00a0Para estudiar c\u00f3mo funciona este tejido es importante comprender\u00a0<\/span>primero\u00a0<\/span>su forma tridimensional y su mec\u00e1nica<\/span>\u00a0y, p<\/span>ara\u00a0<\/span>ello<\/span>, es necesario trabajar con modelos\u00a0<\/span>in vitro<\/span><\/i>\u00a0<\/span>capaces de imitar\u00a0<\/span>las condiciones que se encuentran en nuestro cuerp<\/span>o<\/span>.\u00a0<\/span>\u00a0<\/span><\/p>\n

En la actualidad,\u00a0<\/span>e<\/span>sto es<\/span>\u00a0posible<\/span>\u00a0gracias a<\/span>\u00a0los<\/span>\u00a0<\/span>distintos<\/span>\u00a0modelos 3D desarrollados hasta la fecha. Sin embargo, los principios de ingenier\u00eda que\u00a0<\/span>rigen la forma y la mec\u00e1nica epitelial en 3D\u00a0<\/span>siguen siendo desconocidos<\/span>.\u00a0<\/span>Por ello,<\/span>\u00a0<\/span>el proyecto\u00a0<\/span>\u201c<\/span>EpiFold<\/span>\u201d<\/span>\u00a0<\/span>desempe\u00f1ar\u00e1<\/span>\u00a0<\/span>un papel crucial\u00a0<\/span>para desvelar<\/span>\u00a0estos principios.<\/span>\u00a0<\/span><\/p>\n

E<\/span>n concreto,\u00a0<\/span>este\u00a0<\/span>proyecto tiene como objetivo revelar los principios mec\u00e1nicos por los cuales\u00a0<\/span>el tejido epitelial<\/span>\u00a0adopta y mantiene su forma<\/span>.<\/span>\u00a0<\/span>M<\/span>ediante la\u00a0<\/span>ingenier\u00eda<\/span>\u00a0de tejidos<\/span>\u00a0<\/span>in vitro<\/span><\/i>, Xavier\u00a0<\/span>Trepat<\/span>\u00a0y su equipo<\/span>,<\/span>\u00a0esperan comprender c\u00f3mo estas estructuras 3D se construyen\u00a0<\/span>in vivo<\/span><\/i>,<\/span>\u00a0para as\u00ed<\/span>\u00a0pod<\/span>er<\/span>\u00a0dirigir su\u00a0<\/span>formaci\u00f3n<\/span>.\u00a0<\/span>Adem\u00e1s, el<\/span>\u00a0proyecto tambi\u00e9n<\/span>\u00a0<\/span>tendr\u00e1<\/span>\u00a0<\/span>un gran impacto en el<\/span>\u00a0emergente<\/span>\u00a0campo de los\u00a0<\/span>organoides<\/span>,<\/span>\u00a0ya que\u00a0<\/span>estudiar\u00e1<\/span>\u00a0<\/span>la forma y la mec\u00e1nica de los\u00a0<\/span>organoides<\/span>\u00a0intestinales.\u00a0\u00a0<\/span>\u00a0<\/span><\/p>\n

Desarrollando una<\/span><\/b>\u00a0tecnolog\u00eda<\/span><\/b>\u00a0completamente nueva<\/span><\/b>\u00a0<\/span><\/h3>\n

Lo<\/span>\u00a0m\u00e1s<\/span>\u00a0innovador y ambicioso de este proyecto es que estos principios se aplicar\u00e1n\u00a0<\/span>para<\/span>\u00a0<\/span>el\u00a0<\/span>dise\u00f1o de una nueva generaci\u00f3n de dispositivos\u00a0<\/span>bioh\u00edbridos<\/span>\u00a0<\/span>obtenidos\u00a0<\/span>a partir de<\/span>\u00a0tejido epitelial<\/span>\u00a0que\u00a0<\/span>poseer\u00e1n<\/span>\u00a0<\/span>una capacidad \u00fanica<\/span>\u00a0para potenciar<\/span>\u00a0<\/span>funciones<\/span>\u00a0<\/span>como<\/span>\u00a0<\/span>la\u00a0<\/span>filtraci\u00f3n,\u00a0<\/span>la\u00a0<\/span>secreci\u00f3n<\/span>,\u00a0<\/span>la\u00a0<\/span>auto regeneraci\u00f3n<\/span>\u00a0<\/span>o\u00a0<\/span>la\u00a0<\/span>propulsi\u00f3n<\/span>\u00a0<\/span>en<\/span>\u00a0robots blandos.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

Este proyecto ser\u00e1 el punto de partida de una tecnolog\u00eda completamente nueva llamada \u00ab<\/span>Epiflu\u00eddica<\/span>\u00bb que explotar\u00e1 la capacidad excepcional de detecci\u00f3n y actuaci\u00f3n de las c\u00e9lulas epiteliales para dise\u00f1ar\u00a0<\/span>estos\u00a0<\/span>dispositivos\u00a0<\/span>bioh\u00edbridos<\/span>.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

E<\/span>stos<\/span>\u00a0<\/span>microrrobots<\/span>\u00a0<\/span>\u00fanicos<\/span>,<\/span>\u00a0construidos<\/span>\u00a0con hidrogeles y capas epiteliales<\/span>,<\/span>\u00a0ser\u00e1n capaces de mantener<\/span>\u00a0<\/span>las propiedades multifuncionales y\u00a0<\/span>auto regenerativas<\/span>\u00a0de<\/span>l\u00a0<\/span>epitelio<\/span>, adem\u00e1s de poder<\/span>\u00a0<\/span>detectar, absorber, secretar, filtrar y realizar actividades enzim\u00e1ticas.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

\u201cCuando una pieza de un robot actual se rompe no tenemos otra opci\u00f3n que substituirla.\u00a0<\/span>En cambio, c<\/span>on robots biol\u00f3gicos<\/span>\u00a0<\/span>podemos conseguir que las piezas se\u00a0<\/span>autor<\/span>r<\/span>eparen<\/span>,\u00a0<\/span>ya que\u00a0<\/span>los tejidos vivos tienen capacidad de regeneraci\u00f3n gracias a sus c\u00e9lulas madre\u201d,\u00a0<\/span>expone\u00a0<\/span>Trepat<\/span>.\u00a0<\/span>\u00a0<\/span><\/p>\n

En este mismo sentido, el experto a\u00f1ade que\u00a0<\/span>\u201c<\/span>g<\/span>racias a miles de a\u00f1os de evoluci\u00f3n, los tejidos vivos son capaces de ejecutar tareas m\u00e1s precisas y eficientes que los dispositivos dise\u00f1ados por humanos<\/span>\u201d, por ello,<\/span>\u00a0<\/span>\u201cqueremos\u00a0<\/span>explotar esta capacidad natural de los tejidos para desarrollar robots\u00a0<\/span>multifuncionales<\/span>\u201d<\/span>, concluye\u00a0Trepat.\u00a0<\/span>\u00a0<\/span><\/p>\n

Las\u00a0<\/span>codiciadas ERC\u00a0<\/span>Advanced<\/span>\u00a0<\/span>G<\/span>rants\u00a0<\/span>se otorgan a investigadores\u00a0<\/span>de la UE\u00a0<\/span>con un\u00a0<\/span>dilatado historial de<\/span>\u00a0logros cient\u00edficos en los \u00faltimos 10 a\u00f1os<\/span>,<\/span>\u00a0<\/span>con el objetivo de<\/span>\u00a0apoyar<\/span>\u00a0<\/span>\u00a0proyectos\u00a0de vanguardia de diferentes tem\u00e1ticas<\/span>.<\/span>\u00a0<\/span>Se premian\u00a0<\/span>proyectos con un\u00a0<\/span>fuerte<\/span>\u00a0componente de multidisciplinariedad y con aplicaciones innovadoras en campos\u00a0<\/span>emergentes<\/span>.<\/span>\u00a0<\/span>En<\/span>\u00a0esta convocatoria<\/span>,<\/span>\u00a0se presentaron<\/span>\u00a0un total de\u00a0<\/span>1881<\/span>\u00a0propuestas<\/span>,<\/span>\u00a0de las cuales\u00a0<\/span>185<\/span> han sido seleccionadas para su financiaci\u00f3n.<\/span>\u00a0<\/span>C<\/span>on esta nueva beca<\/span>, a<\/span>\u00a0d\u00eda de hoy, el IBEC ha recibido financiaci\u00f3n del ERC para el desa<\/span>rrollo de\u00a0<\/span>19<\/span>\u00a0proyectos\u00a0<\/span>de investigaci\u00f3n.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"El investigador del Instituto de Bioingenier\u00eda de Catalunya (IBEC), Xavier Trepat, ha recibido la prestigiosa beca ERC Advanced Grant, otorgada por el Consejo Europeo de Investigaci\u00f3n (ERC) y dotada con 2,5 millones de euros. <\/h3>\n

El experto y su grupo destinar\u00e1n estos recursos a estudiar las propiedades mec\u00e1nicas del epitelio en 3D y a sentar las bases de una tecnolog\u00eda pionera llamada \u00abEpiflu\u00eddica\u00bb, que permitir\u00e1 dise\u00f1ar robots biol\u00f3gicos. <\/p>\n","protected":false},"author":4,"featured_media":73024,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[921,1411,826,920,1144],"post_formats":[],"class_list":["post-73002","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-advanced-grant-es","tag-erc-grant","tag-european-research-council-es","tag-robots-biologicos","tag-xavier-trepat-es"],"yoast_head":"\nEl investigador Xavier Trepat recibe la ERC Advanced Grant para crear las bases de una nueva generaci\u00f3n de robots biol\u00f3gicos - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/xavier-trepat-receives-the-erc-advanced-grant-to-lay-the-basis-of-a-new-generation-of-biological-robots\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El investigador Xavier Trepat recibe la ERC Advanced Grant para crear las bases de una nueva generaci\u00f3n de robots biol\u00f3gicos - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"El investigador del Instituto de Bioingenier\u00eda de Catalunya (IBEC), Xavier Trepat, ha recibido la prestigiosa beca ERC Advanced Grant, otorgada por el Consejo Europeo de Investigaci\u00f3n (ERC) y dotada con 2,5 millones de euros. 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