{"id":73628,"date":"2020-02-26T12:12:40","date_gmt":"2020-02-26T11:12:40","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=73628"},"modified":"2020-06-15T13:19:45","modified_gmt":"2020-06-15T11:19:45","slug":"investigadores-del-ibec-contribuyen-a-hacer-los-experimentos-con-globulos-rojos-mas-realistas","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/investigadores-del-ibec-contribuyen-a-hacer-los-experimentos-con-globulos-rojos-mas-realistas\/","title":{"rendered":"Investigadores del IBEC contribuyen a hacer los experimentos con gl\u00f3bulos rojos m\u00e1s realistas"},"content":{"rendered":"

El proyecto,\u00a0<\/span>que ha sido bautizado con el nombre de<\/span>\u00a0EVIDENCE<\/a>, est\u00e1 dirigido por el profesor Dr. Lars\u00a0<\/span>Kaestner<\/span>\u00a0de la Universidad de\u00a0<\/span>Saarland<\/span>\u00a0(Alemania) y<\/span>\u00a0cuenta con la colaboraci\u00f3n de expertos<\/span>\u00a0de Francia, Suiza, los Pa\u00edses Bajos y\u00a0<\/span>el Reino Unido<\/span>.\u00a0<\/span>Todos ellos ahondar\u00e1n durante los pr\u00f3ximos a\u00f1os<\/span>\u00a0en la naturaleza de los gl\u00f3bulos rojos<\/span>\u00a0para averiguar\u00a0<\/span>c\u00f3mo\u00a0<\/span>estos se ven afectados por lo que ocurre en\u00a0<\/span>el e<\/span>ntorno extracelular<\/span>.<\/span>\u00a0<\/span><\/p>\n

Durante la elaboraci\u00f3n del proyecto<\/span>,<\/span>\u00a0al que la UE destina 4 millones de euros,<\/span>\u00a0los expertos\u00a0<\/span>se servir\u00e1n de<\/span>\u00a0modelos matem\u00e1ticos para\u00a0<\/span>intentar comprender mejor<\/span>\u00a0c\u00f3mo fluye la sangre en el cuerpo, lo que podr\u00eda servir\u00a0<\/span>de\u00a0<\/span>base para\u00a0<\/span>otros<\/span>\u00a0estudios experimentales\u00a0<\/span>sobre el<\/span>\u00a0flujo sangu\u00edneo.\u00a0<\/span>\u00a0<\/span><\/p>\n

Entre los\u00a0<\/span>objetivos espec\u00edficos de este programa\u00a0<\/span>figuran<\/span>\u00a0el desarrollo de t\u00e9cnicas de diagn\u00f3stico novedosas para\u00a0<\/span>curar trastornos an\u00e9micos raros<\/span>\u00a0como la anemia falciforme<\/span>\u00a0o la producci\u00f3n de gl\u00f3bulos rojos<\/span>\u00a0en el laboratorio, algo que\u00a0 para\u00a0<\/span>Kaestner<\/span>, el\u00a0<\/span>l\u00edder\u00a0<\/span>del proyecto<\/span>\u00a0EVIDENCE<\/span>,\u00a0<\/span>ser\u00eda clave\u00a0<\/span>para el sector de transfusiones<\/span>.<\/span>\u00a0<\/span><\/p>\n

\u201cAunque ya existe la<\/span>\u00a0tecnolog\u00eda\u00a0<\/span>necesaria<\/span>\u00a0para producir sangre artificial, un solo lote puede costar varios cientos de miles de euros.\u00a0<\/span>Por ello<\/span>, mejo<\/span>rar el proceso de producci\u00f3n y\u00a0<\/span>hacer<\/span>lo m\u00e1s rentable<\/span>\u00a0<\/span>ayudar\u00eda a complementar las<\/span>\u00a0fuentes naturales de sangre<\/span>\u00a0y a adaptar los sustitutos para tratar las afecciones m\u00e1s complejas<\/span>\u201d, apunta en este sentido\u00a0<\/span>Kaestner<\/span>.<\/span>\u00a0<\/span><\/p>\n

Los gl\u00f3bulos rojos (eritrocitos) son\u00a0<\/span>las c\u00e9lulas m\u00e1s numerosas de la sangre<\/span>.\u00a0<\/span>Su funci\u00f3n es la de transportar<\/span>\u00a0ox\u00edgeno a los lugare<\/span>s del cuerpo donde se necesita, es decir,\u00a0<\/span>a las c\u00e9lulas que form<\/span>an nuestros m\u00fasculos y \u00f3rganos, con lo que son esenciales para la vida. Sin embargo, si\u00a0<\/span>el organismo contiene\u00a0<\/span>n\u00famero<\/span>\u00a0de\u00a0<\/span>gl\u00f3bulos rojos\u00a0<\/span>demasiado alto o demasiado bajo,\u00a0<\/span>\u00a0<\/span>puede que \u00e9stos se deformen al fluir o que su\u00a0<\/span>funci\u00f3n se ve<\/span>a afectada, lo que puede dar lugar a muchas enfermedades<\/span>.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

Por ello, comprender<\/span>\u00a0c\u00f3mo se comportan los eritrocitos en el sistema circulatorio\u00a0<\/span>es vital para la cura de estas afecciones<\/span>.\u00a0<\/span>El problema est\u00e1 en que\u00a0<\/span>\u00e9ste entorno es\u00a0<\/span>dif\u00edcil\u00a0<\/span>de\u00a0<\/span>reproducir\u00a0<\/span>en el laboratorio, donde en la mayor\u00eda de casos\u00a0<\/span>la sangre se estudia\u00a0<\/span>a trav\u00e9s de\u00a0<\/span>portaobjetos<\/span>\u00a0y no\u00a0<\/span>mientras fluye.<\/span>\u00a0<\/span><\/p>\n

En<\/span>\u00a0es<\/span>t<\/span>as condiciones<\/span>, algunos eritrocitos<\/span>\u00a0ya est\u00e1n muertos, lo que impide que los cient\u00edficos\u00a0<\/span>vean c\u00f3mo se comportan<\/span>\u00a0<\/span>estas c\u00e9lulas<\/span>\u00a0en el entorno real<\/span>. No obstante,\u00a0<\/span>en\u00a0<\/span>las \u00faltimas d\u00e9cadas se han realizado avances importantes en este sentido. As\u00ed, por ejemplo, mientras hace 20 a\u00f1os era impensable medir la cantidad de gl\u00f3bulos rojos que hay en<\/span>\u00a0una muestra de<\/span>\u00a0sangre, hacerlo ahora s\u00ed que es posible<\/span>\u00a0y la informaci\u00f3n que se tiene de estas c\u00e9lulas es cada vez m\u00e1s detallada.<\/span>\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\"\"Expertos del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) liderados por Josep Samitier, el director del Instituto, est\u00e1n inmersos en un proyecto financiado por la Uni\u00f3n Europea (UE) que tiene como objetivo estudiar los gl\u00f3bulos rojos en las condiciones fisiol\u00f3gicas m\u00e1s cercanas a la realidad posible. <\/h3>\n","protected":false},"author":4,"featured_media":73755,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[970,1137,969],"post_formats":[],"class_list":["post-73628","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-anemia-es","tag-josep-samitier-es","tag-proyecto-evidence"],"yoast_head":"\nInvestigadores del IBEC contribuyen a hacer los experimentos con gl\u00f3bulos rojos m\u00e1s realistas - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" 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