{"id":77755,"date":"2020-10-02T11:12:50","date_gmt":"2020-10-02T09:12:50","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=77755"},"modified":"2020-11-13T20:22:25","modified_gmt":"2020-11-13T19:22:25","slug":"bioingenieria-para-luchar-contra-la-covid-19","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/bioingenieria-para-luchar-contra-la-covid-19\/","title":{"rendered":"Bioingenier\u00eda para luchar contra la Covid-19"},"content":{"rendered":"<p><img decoding=\"async\" class=\"wp-image-77746 alignleft lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-300x300.png\" alt=\"\" width=\"341\" height=\"341\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-300x300.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-150x150.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-45x45.png 45w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec.png 470w\" data-sizes=\"(max-width: 341px) 100vw, 341px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 341px; --smush-placeholder-aspect-ratio: 341\/341;\" \/>La pandemia del SARS-CoV-2 se ha cobrado la vida de cientos de miles de personas en todo el mundo y se ha convertido en una carga sin precedentes para la salud p\u00fablica, nuestra sociedad y la econom\u00eda global. Para proporcionar terapias efectivas para la pandemia actual y futuros brotes de otros tipos de coronavirus, el proyecto MAD-CoV-2 ha reunido un equipo multidisciplinario de investigadores internacionales y empresas que trabajar\u00e1n juntos durante cuatro a\u00f1os con una financiaci\u00f3n total de 6.405.168,75\u20ac de los cuales la Comisi\u00f3n Europea aporta un total de 3.749.668.75 \u20ac y el resto empresas privadas.<\/p>\n<p>El proyecto est\u00e1 compuesto por 9 socios, el Instituto Nacional de Veterinaria en Suecia, que lidera el proyecto, junto con el Inserm Transfert SA de Francia, el Instituto Fuer Molekulare Biotechnologie GMGH, el Health GmbH y APEIRON Biologics AG, los tres de Austria, el Justus-Liebig-Universitaet Giessen en Alemania, STEMCELL Technologies UK LTD del Reino Unido y Vironova AB de Suecia. N\u00faria Montserrat y su equipo se unen a este consorcio como un grupo reconocido por su trabajo en ingenier\u00eda de tejidos y desarrollo de organoides humanos &#8211; modelos celulares que simulan la complejidad de tales \u00f3rganos en la placa de cultivo- a partir de c\u00e9lulas madre inducidas.<\/p>\n<p>MAD-CoV 2 identificar\u00e1 nuevas dianas terap\u00e9uticas para el desarrollo r\u00e1pido de nuevos antivirales contra el SARS-CoV-2 y tambi\u00e9n realizar\u00e1 una detecci\u00f3n de alto rendimiento para identificar los factores de interacci\u00f3n entre el virus y las c\u00e9lulas infectadas, que son cr\u00edticos para la replicaci\u00f3n viral. Como resultado, ser\u00e1 posible traducir r\u00e1pidamente este conocimiento en nuevas terapias para combatir el brote actual y de futuros de coronavirus.<\/p>\n<h4><strong>Usando la tecnolog\u00eda de organoides 3D como modelo de infecci\u00f3n<\/strong><\/h4>\n<p>N\u00faria Montserrat y su equipo se centrar\u00e1n en la caracterizaci\u00f3n y validaci\u00f3n de los interactores celulares recientemente identificados, como dianas terap\u00e9uticas mediante el uso de organoides de ri\u00f1\u00f3n. Espec\u00edficamente, se trabajar\u00e1 en la identificaci\u00f3n de p\u00e9ptidos y compuestos antivirales que interact\u00faan con la prote\u00edna S del virus SARS-CoV-2. Gracias a la experiencia del consorcio en la generaci\u00f3n de organoides a partir de c\u00e9lulas madre adultas y de c\u00e9lulas madre pluripotenciales, se evaluar\u00e1 la efectividad de los compuestos mediante el uso de modelos de organoides de pulm\u00f3n, colon y ri\u00f1\u00f3n.<\/p>\n<p>Tambi\u00e9n se llevar\u00e1n a cabo m\u00e1s investigaciones para prevenir posibles futuras epidemias causadas por otros coronavirus y de esta manera identificar el tal\u00f3n de Aquiles com\u00fan y desarrollar medicamentos y estrategias disruptivas para combatirlas.<\/p>\n<p>Este proyecto naci\u00f3 como parte de la respuesta de la UE a la actual pandemia causada por el coronavirus como parte del programa H2020. La \u201cIniciativa de Medicamentos Innovadores\u201d (IMI) anunci\u00f3 esta nueva convocatoria de una inversi\u00f3n de 45 millones de euros en fondos de investigaci\u00f3n para aquellos equipos que pueden demostrar su capacidad para desarrollar pruebas y\/o tratamientos para la COVID-19 que puedan llegar al mercado lo m\u00e1s r\u00e1pido posible. Finalmente, se presentaron 144 candidaturas y debido a la alta calidad de las propuestas recibidas, el IMI decidi\u00f3 aumentar la financiaci\u00f3n hasta los 72 millones de euros, gracias a la participaci\u00f3n de las empresas de la <a href=\"https:\/\/www.efpia.eu\/about-us\/\" target=\"_blank\" rel=\"noopener noreferrer\">EFPIA<\/a> y de otras organizaciones, que ir\u00e1n destinados a los 8 proyectos seleccionados.<\/p>\n","protected":false},"excerpt":{"rendered":"<h3>Ayer tuvo lugar la reuni\u00f3n de lanzamiento del proyecto europeo MAD-CoV 2 en el que participa el grupo dirigido por la profesora de investigaci\u00f3n ICREA N\u00faria Montserrat del IBEC.<\/h3>\n<p>Bajo el nombre de \u00abEnfoques modernos para el desarrollo de antivirales contra el SARS-CoV 2\u00bb (MAD-CoV 2 por sus siglas en ingl\u00e9s), el proyecto se centrar\u00e1 en desarrollar y proporcionar herramientas terap\u00e9uticas para el actual brote de COVID-19. <\/p>\n","protected":false},"author":4,"featured_media":77746,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1246,244,1223],"post_formats":[],"class_list":["post-77755","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-bioengineering-es","tag-bioingenieria-es","tag-covid-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bioingenier\u00eda para luchar contra la Covid-19 - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/bioingenieria-para-luchar-contra-la-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta 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