{"id":78102,"date":"2020-10-13T10:39:43","date_gmt":"2020-10-13T08:39:43","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=78102"},"modified":"2020-11-13T20:22:08","modified_gmt":"2020-11-13T19:22:08","slug":"un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\/","title":{"rendered":"Un proyecto del IBEC sobre COVID-19 recibe financiaci\u00f3n de la Fundaci\u00f3n BBVA"},"content":{"rendered":"

\"\"\u00a0Los veinte proyectos seleccionados para poner freno al coronavirus implican a m\u00e1s de 400 investigadores, los cuales abordar\u00e1n desde distintos \u00e1ngulos los mecanismos de infecci\u00f3n, diagn\u00f3stico y tratamiento de esta enfermedad. Tambi\u00e9n se estudiar\u00e1 el impacto psicosocial y econ\u00f3mico derivado de la pandemia.<\/p>\n

Para abordar la actual pandemia de Covid-19 hace falta estudiar sus diversas facetas con un enfoque multidisciplinar. Para ello, el grupo de \u201cPluripotencia para la regeneraci\u00f3n de \u00f3rganos\u201d, dirigido por la Profesora de Investigaci\u00f3n ICREA Nuria Montserrat, aportar\u00e1 su experiencia en la generaci\u00f3n de mini\u00f3rganos humanos mediante t\u00e9cnicas de bioingenier\u00eda para entender c\u00f3mo se lleva a cabo la infecci\u00f3n por coronavirus.<\/p>\n

Gracias a la subvenci\u00f3n de 250.000 euros de la Fundaci\u00f3n BBVA, el grupo de Nuria Montserrat, junto con Josef Penninger del Instituto de Biotecnolog\u00eda Molecular de Austria y Ali Mirazimi del Instituto Karolinska, en Suecia, estudiar\u00e1n c\u00f3mo el SARS-CoV-2 infecta a las c\u00e9lulas, para ello, utilizar\u00e1n \u2018minirri\u00f1ones\u2019 generados a partir de c\u00e9lulas madre humanas. En estos organoides ser\u00e1 posible \u201cabrir y cerrar\u201d a voluntad, mediante la t\u00e9cnica de edici\u00f3n gen\u00e9tica CRISPR, las prote\u00ednas que usa el virus como puerta de entrada a las c\u00e9lulas -ACE2, entre otras-, y estudiar as\u00ed el mecanismo de infecci\u00f3n que \u00e9ste utiliza. Adem\u00e1s, los investigadores tambi\u00e9n estudiar\u00e1n las v\u00edas moleculares que se activan una vez el virus infecta la c\u00e9lula. El uso de estos organoides, que recogen la complejidad del \u00f3rgano real, permite acelerar un tipo de investigaci\u00f3n que de otra manera llevar\u00eda a\u00f1os.<\/p>\n

El pasado mes de abril<\/a>, la investigadora, junto a otros centros de investigaci\u00f3n internacionales, ya demostraron que los organoides renales conten\u00edan grupos de c\u00e9lulas que expresaban ACE2 de manera similar a la que se observa en el tejido nativo, y despu\u00e9s, procedieron a infectarlo con SARS-CoV-2. Una vez obtuvieron estos minirri\u00f1ones infectados, aplicaron diferentes f\u00e1rmacos para inhibir las infecciones por SARS-CoV-2 y reducir su carga viral.<\/p>\n

M\u00e1s sobre la convocatoria de Ayudas de la Fundaci\u00f3n BBVA<\/strong><\/h4>\n

Todos los proyectos seleccionados tienen un objetivo com\u00fan: hacer frente a la actual pandemia causada por la Covid-19. Por ello, tras evaluar los casi 1.000 proyectos presentados, cinco comisiones de expertos han acordado la concesi\u00f3n de cuatro ayudas en Biomedicina (250.000 euros por proyecto); cuatro en Big Data e Inteligencia Artificial (150.000 euros por proyecto); cuatro en Ecolog\u00eda y Veterinaria (100.000 euros por proyecto); cuatro en Econom\u00eda y Ciencias Sociales (100.000 euros por proyecto); y cuatro en Humanidades (75.000 euros por proyecto).<\/p>\n

El proyecto \u201cIdentifying SARS-CoV-2- host cell interactions exploiting CRISPR\/Cas9 engineered human organoids: through the development of specific therapies against COVID19\u201d recibir\u00e1 financiaci\u00f3n del programa AYUDAS FUNDACI\u00d3N BBVA A EQUIPOS DE INVESTIGACI\u00d3N CIENT\u00cdFICA SARS-CoV-2 y COVID-19\u201d<\/em><\/p>\n

M\u00e1s informaci\u00f3n aqu\u00ed<\/a>.<\/p>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

Nuria Montserrat, y su equipo de investigaci\u00f3n en el IBEC, reciben financiaci\u00f3n de la Fundaci\u00f3n BBVA para liderar un proyecto de investigaci\u00f3n en COVID-19.<\/h3>\n

El proyecto de Montserrat es uno de los 20 proyectos seleccionados de entre casi 1000 propuestas que se presentaron a la convocatoria, que recibir\u00e1n un total de 2,7 millones de euros.<\/p>\n","protected":false},"author":4,"featured_media":78103,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1285,1223,1124],"post_formats":[],"class_list":["post-78102","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-bbva","tag-covid-es","tag-nuria-montserrat-es-2"],"yoast_head":"\nUn proyecto del IBEC sobre COVID-19 recibe financiaci\u00f3n de la Fundaci\u00f3n BBVA - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un proyecto del IBEC sobre COVID-19 recibe financiaci\u00f3n de la Fundaci\u00f3n BBVA - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Nuria Montserrat, y su equipo de investigaci\u00f3n en el IBEC, reciben financiaci\u00f3n de la Fundaci\u00f3n BBVA para liderar un proyecto de investigaci\u00f3n en COVID-19. El proyecto de Montserrat es uno de los 20 proyectos seleccionados de entre casi 1000 propuestas que se presentaron a la convocatoria, que recibir\u00e1n un total de 2,7 millones de euros.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/es\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-13T08:39:43+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-13T19:22:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/NMontserrat1_group-e1602578284141.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"333\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Un proyecto del IBEC sobre COVID-19 recibe financiaci\u00f3n de la Fundaci\u00f3n BBVA\",\"datePublished\":\"2020-10-13T08:39:43+00:00\",\"dateModified\":\"2020-11-13T19:22:08+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\\\/\"},\"wordCount\":502,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2020\\\/10\\\/NMontserrat1_group-e1602578284141.jpg\",\"keywords\":[\"BBVA\",\"COVID-19\",\"Nuria Montserrat\"],\"articleSection\":[\"Noticias institucionales\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/es\\\/un-proyecto-del-ibec-sobre-covid-19-recibe-financiacion-de-la-fundacion-bbva\\\/\",\"name\":\"Un proyecto del IBEC sobre COVID-19 recibe financiaci\u00f3n de la Fundaci\u00f3n BBVA - 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