{"id":80567,"date":"2020-12-18T17:56:20","date_gmt":"2020-12-18T16:56:20","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=80567"},"modified":"2020-12-21T13:54:41","modified_gmt":"2020-12-21T12:54:41","slug":"el-ibec-participa-en-un-proyecto-europeo-con-el-objetivo-de-acelerar-la-investigacion-clinica-para-la-discapacidad-visual","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/el-ibec-participa-en-un-proyecto-europeo-con-el-objetivo-de-acelerar-la-investigacion-clinica-para-la-discapacidad-visual\/","title":{"rendered":"El IBEC participa en un proyecto europeo con el objetivo de acelerar la investigaci\u00f3n cl\u00ednica para la discapacidad visual"},"content":{"rendered":"<p><img decoding=\"async\" class=\"alignleft size-large wp-image-80482 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-1024x1024.png\" alt=\"\" width=\"900\" height=\"900\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-1024x1024.png 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-300x300.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-150x150.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-768x768.png 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-45x45.png 45w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox.png 1298w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/900;\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>La discapacidad visual afecta a m\u00e1s de 250 millones de personas en todo el mundo, y treinta y seis millones de personas son ciegas. La degeneraci\u00f3n de la retina a menudo es incurable y el envejecimiento de la poblaci\u00f3n en todo el mundo es un desaf\u00edo social y econ\u00f3mico importante.<\/p>\n<p>Debido a las limitaciones tecnol\u00f3gicas actuales, los ojos solo pueden mantenerse a 4\u00baC durante un per\u00edodo de 48 horas antes de una degradaci\u00f3n irreversible. Esto limita en gran medida su uso para la experimentaci\u00f3n, particularmente para probar la efectividad de nuevos medicamentos y tratamientos.<\/p>\n<p>Ahora, un consorcio interdisciplinar compuesto por siete centros de investigaci\u00f3n internacionales trabajar\u00e1 para encontrar nuevas soluciones en el marco del Proyecto Europeo ECaBOX. El proyecto ha sido premiado con 3,5 millones de euros por el programa de investigaci\u00f3n \u201cFuture and Emerging Technologies Open research FET-Open\u00bb de la Uni\u00f3n Europea, que financia tecnolog\u00edas radicalmente nuevas.<\/p>\n<p>El proyecto ECaBOX ser\u00e1 coordinado por Pia Cosma en el CRG en colaboraci\u00f3n con otros dos centros de investigaci\u00f3n catalanes: Ricardo Casaroli de la Universitat de Barcelona y <strong>Nuria Montserrat, profesora de investigaci\u00f3n ICREA y l\u00edder de grupo del Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC)<\/strong>. Otros colaboradores internacionales incluyen King&#8217;s College London (KCL) en el Reino Unido, la Asociaci\u00f3n para el Avance de la Ingenier\u00eda de Tejidos y Tecnolog\u00edas y Terapias Basadas en C\u00e9lulas (A4TEC) en Portugal, AFERETICA en Italia y la Universidad de BarIlan (BIU) en Israel.<\/p>\n<h2><strong><span class=\"TextRun SCXW68992641 BCX0\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW68992641 BCX0\">\u00a0<\/span><\/span><span class=\"TextRun SCXW68992641 BCX0\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW68992641 BCX0\">El Proyecto\u00a0<\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW68992641 BCX0\">ECaBOX<\/span><span class=\"NormalTextRun SCXW68992641 BCX0\">\u00a0y el dispositivo<\/span><\/span><span class=\"EOP SCXW68992641 BCX0\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/strong><\/h2>\n<p><span data-contrast=\"auto\">Si bien los avances en\u00a0<\/span><span data-contrast=\"auto\">organoides<\/span><span data-contrast=\"auto\"> humanos (<\/span><span data-contrast=\"none\">modelos celulares que simulan la complejidad de tales \u00f3rganos en la placa de cultivo<\/span><span data-contrast=\"auto\">) est\u00e1n imitando con \u00e9xito la funci\u00f3n del ojo, todav\u00eda presentan limitaciones al encapsular la complejidad fisiol\u00f3gica del ojo, como su<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0sistema<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0inmunol\u00f3gico, vascular y metab\u00f3lico.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">El nuevo m\u00e9todo desarrollado dentro del proyecto\u00a0ECaBOX\u00a0evitar\u00e1 estas limitaciones reviviendo los ojos y manteni\u00e9ndolos sanos durante al menos un mes, ayudando a los investigadores a evaluar la eficacia, eficiencia y seguridad de las nuevas terapias regenerativas y las pruebas de f\u00e1rmacos.\u00a0<\/span><span data-contrast=\"auto\">Usa<\/span><span data-contrast=\"auto\">r<\/span><span data-contrast=\"auto\">\u00a0ojos resucitados tambi\u00e9n puede eludir varias restricciones \u00e9ticas de las pruebas precl\u00ednicas con animales, as\u00ed como la experimentaci\u00f3n con humanos.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">El dispositivo, denominado\u00a0<\/span><span data-contrast=\"auto\">ECaBox<\/span><span data-contrast=\"auto\">, ser\u00e1 una caja c\u00fabica transparente que imita<\/span><span data-contrast=\"auto\">r\u00e1<\/span><span data-contrast=\"auto\">\u00a0las condiciones del ojo humano vivo, manteniendo la temperatura del ojo y los niveles de pH mientras evita los co\u00e1gulos de sangre y elimina los desechos metab\u00f3licos y las toxinas. Se espera que se construya un prototipo temprano del dispositivo a fines de 2023.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0<\/p>\n<h3>Nuria Montserrat y su equipo en el IBEC participan en un consorcio internacional que tiene como objetivo desarrollar un dispositivo para acelerar la investigaci\u00f3n cl\u00ednica de enfermedades oculares, a partir de ojos humanos de donantes. <\/h3>\n","protected":false},"author":4,"featured_media":80484,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[710,1124],"post_formats":[],"class_list":["post-80567","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-colaboraciones-clinicas","tag-nuria-montserrat-es-2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>El IBEC participa en un proyecto europeo con el objetivo de acelerar la investigaci\u00f3n cl\u00ednica para la discapacidad visual - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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