{"id":81577,"date":"2021-02-08T10:41:58","date_gmt":"2021-02-08T09:41:58","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=81577"},"modified":"2021-02-09T12:31:54","modified_gmt":"2021-02-09T11:31:54","slug":"premio-para-doctorado-sobre-mecanobiologia-en-el-ibec","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/premio-para-doctorado-sobre-mecanobiologia-en-el-ibec\/","title":{"rendered":"Premio para doctorado sobre mecanobiolog\u00eda en el IBEC"},"content":{"rendered":"<p>El trabajo premiado ha sido dirigido por Pere Roca-Cusachs, investigador principal en el IBEC, y Profesor Agregado de la Facultad de Medicina y Ciencias de la Salud de la UB.<\/p>\n<figure id=\"attachment_81558\" aria-describedby=\"caption-attachment-81558\" style=\"width: 700px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-81558 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/02\/cover2-300x196.png\" alt=\"\" width=\"710\" height=\"464\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/02\/cover2-300x196.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/02\/cover2-768x502.png 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/02\/cover2-150x98.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/02\/cover2.png 989w\" data-sizes=\"(max-width: 710px) 100vw, 710px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 710px; --smush-placeholder-aspect-ratio: 710\/464;\" \/><figcaption id=\"caption-attachment-81558\" class=\"wp-caption-text\"><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:2,&quot;335551620&quot;:2,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">Roger Oria, ganador del XXIV Premio Claustro de Doctores de la UB con una tesis sobre mecanobiolog\u00eda.\u00a0<\/span><\/figcaption><\/figure>\n<p><span data-contrast=\"auto\">La tesis doctoral con el t\u00edtulo <\/span><a href=\"https:\/\/www.educacion.gob.es\/teseo\/imprimirFicheroTesis.do?idFichero=3eOTwvIw94M%3D\" target=\"_blank\" rel=\"noopener\"><i><span data-contrast=\"none\">Cell sensing of the extracelular environment: Roles of matrix rigidity, ligand density, and ligand distribution<\/span><\/i><\/a><span data-contrast=\"auto\">, gira alrededor de una hip\u00f3tesis sobre c\u00f3mo las c\u00e9lulas son capaces de percibir informaci\u00f3n espacial y f\u00edsica a escala nanom\u00e9trica. Hasta ahora, la hip\u00f3tesis m\u00e1s aceptada defend\u00eda que las c\u00e9lulas pod\u00edan emplear alg\u00fan tipo de mol\u00e9cula patr\u00f3n en ese proceso. En concreto, el trabajo doctoral constata que el mecanismo que utilizan para percibir el medio extracelular est\u00e1 regulado por la detecci\u00f3n de fuerzas que dependen de la distribuci\u00f3n espacial de los ligandos. Esta l\u00ednea de investigaci\u00f3n dentro de la innovadora disciplina de la <\/span><span data-contrast=\"auto\">mecanobiolog\u00eda<\/span><span data-contrast=\"auto\"> puede contribuir a identificar nuevas herramientas para frenar patolog\u00edas que se asocian con la rigidez de los tejidos, como <\/span><span data-contrast=\"auto\">por ejemplo, <\/span><span data-contrast=\"auto\">el c\u00e1ncer.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2><strong>Mecanobiolog\u00eda: una nueva perspectiva de los procesos biol\u00f3gicos\u00a0<\/strong><\/h2>\n<p><span data-contrast=\"auto\">La <\/span><span data-contrast=\"auto\">mecanobiolog\u00eda<\/span><span data-contrast=\"auto\"> es un campo emergente que ha ido tomando fuerza en las \u00faltimas d\u00e9cadas. Cada vez m\u00e1s cient\u00edficos han comenzado a dar atenci\u00f3n a la importancia de la f\u00edsica en el desarrollo de \u00f3rganos y organismos, y han comenzado a definir los mecanismos por los que las c\u00e9lulas detectan, responden y generan fuerzas. En el IBEC, varios grupos de investigaci\u00f3n, entre ellos el del Profesor Pere Roca-<\/span><span data-contrast=\"auto\">Cusachs<\/span><span data-contrast=\"auto\">, son pioneros en este campo, <\/span><span data-contrast=\"auto\">que<\/span><span data-contrast=\"auto\"> adem\u00e1s, es uno de los cuatro ejes de investigaci\u00f3n en el instituto.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Las c\u00e9lulas son capaces de percibir su entorno, y esta capacidad es esencial para mantener la funci\u00f3n de los tejidos y detectar cambios (crecimiento celular, proliferaci\u00f3n tumoral, etc.). A trav\u00e9s de las adhesiones focales, que son estructuras formadas por prote\u00ednas transmembrana y tambi\u00e9n adaptadoras, las c\u00e9lulas se adaptan y detectan las propiedades f\u00edsicas de la matriz extracelular.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<blockquote><p><strong>Las adhesiones focales act\u00faan como una especie de \u201czapatos celulares\u201d, que proporcionan tracci\u00f3n y anclaje a los tejidos de alrededor. Asimismo, las c\u00e9lulas tambi\u00e9n cambian las adhesiones focales para poder adaptarse a los distintos tejidos y sus caracter\u00edsticas ,por ejemplo, los crecimientos tumorales.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>Roger Oria\u00a0<\/strong><\/p>\n<\/blockquote>\n<p><strong>Sobre el premio<br \/>\n<\/strong><span data-contrast=\"auto\">El Premio Claustro de Doctores se cre\u00f3 en 1997 para distinguir las tesis doctorales le\u00eddas y defendidas en la Universidad de Barcelona que supusieran las aportaciones m\u00e1s relevantes al conocimiento humano y el progreso de la ciencia. Con car\u00e1cter anual, el premio quiere dar a conocer y potenciar los trabajos de los j\u00f3venes doctores de la UB y colaborar as\u00ed en la difusi\u00f3n del prestigio acad\u00e9mico y social del t\u00edtulo de doctor, m\u00e1ximo grado acad\u00e9mico que pueden alcanzar los estudiantes dentro de la instituci\u00f3n universitaria.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<h3>Roger Oria gana el XXIV Premio Claustro de Doctores de la Universidad de Barcelona (UB) por su tesis sobre mecanobiolog\u00eda, una disciplina emergente que puede contribuir a identificar nuevas herramientas para frenar patolog\u00edas que se asocian con la rigidez de los tejidos, como por ejemplo, el c\u00e1ncer. <\/h3>\n","protected":false},"author":4,"featured_media":81563,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[1135],"post_formats":[],"class_list":["post-81577","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales","tag-pere-roca-cusachs-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Premio para doctorado sobre mecanobiolog\u00eda en el IBEC - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/premio-para-doctorado-sobre-mecanobiologia-en-el-ibec\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" 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