{"id":82770,"date":"2021-03-11T09:48:05","date_gmt":"2021-03-11T08:48:05","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=82770"},"modified":"2021-03-11T09:48:05","modified_gmt":"2021-03-11T08:48:05","slug":"ibec-y-la-asociacion-nen-aunan-fuerzas-contra-el-neuroblastoma-infantil","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/es\/ibec-y-la-asociacion-nen-aunan-fuerzas-contra-el-neuroblastoma-infantil\/","title":{"rendered":"IBEC y la Asociaci\u00f3n NEN a\u00fanan fuerzas contra el neuroblastoma infantil"},"content":{"rendered":"

\"\"<\/p>\n

El Neuroblastoma es un c\u00e1ncer poco com\u00fan del sistema nervioso simp\u00e1tico, la red nerviosa que env\u00eda los mensajes desde el cerebro al resto del cuerpo. Es el tumor m\u00e1s frecuente durante los 2 primeros a\u00f1os de vida. En total, el neuroblastoma representa el 8-10% de los tumores pedi\u00e1tricos.<\/p>\n

Debido a que el neuroblastoma var\u00eda ampliamente de un paciente a otro, existe la necesidad de modelos y terapias m\u00e1s efectivas para su estudio y tratamiento. Sin embargo, la dificultad de replicar con fidelidad el complejo entorno del c\u00e1ncer humano es una barrera cr\u00edtica para comprender los mecanismos subyacentes a la progresi\u00f3n de esta enfermedad y, adem\u00e1s, dificulta la posibilidad de evaluar las terapias dirigidas contra el c\u00e1ncer.<\/p>\n

A lo largo de d\u00e9cadas se han realizado numerosos estudios para comprender las v\u00edas moleculares de la patog\u00e9nesis del c\u00e1ncer, as\u00ed como para evaluar medicamentos contra el c\u00e1ncer utilizando cultivos celulares y animales como modelos de la enfermedad. Sin embargo, la mayor\u00eda de estos estudios no han trascendido a pacientes. De este modo, solo un 5% de los f\u00e1rmacos que funcionaban en modelos animales mostraron actividad antitumoral en ensayos cl\u00ednicos.<\/p>\n

Ingenier\u00eda contra el neuroblastoma<\/strong><\/h2>\n

En el caso del neuroblastoma, la vascularizaci\u00f3n del tumor desempe\u00f1a un papel crucial en la regulaci\u00f3n del crecimiento del mismo, pero que a\u00f1ade un factor m\u00e1s de complejidad a su estudio y a la b\u00fasqueda de soluciones.<\/p>\n

En este contexto, la investigadora del IBEC, la Dra. \u00c1ranzazu Vilasante desarroll\u00f3 en 2017 el primer modelo de neuroblastoma humano vascularizado, mediante t\u00e9cnicas de ingenier\u00eda de c\u00e1ncer, que es capaz de recapitular in vitro el mimetismo vasculog\u00e9nico y la presencia de un tipo de c\u00e9lulas conocidas como TEC.<\/p>\n

IBEC y la Asociaci\u00f3n NEN a\u00fanan fuerzas<\/strong><\/h2>\n

\"\"Con el objetivo de tratar de avanzar en la b\u00fasqueda de modelos y soluciones para el neuroblastoma, la asociaci\u00f3n de Familiares y Amigos de Ni\u00f1os Enfermos de Neuroblastoma (NEN) e IBEC firmaron el pasado jueves 4 de marzo, un acuerdo de colaboraci\u00f3n para buscar nuevos marcadores terap\u00e9uticos, mediante la generaci\u00f3n de modelos basados en t\u00e9cnicas de ingenier\u00eda de c\u00e1ncer. Al acto de formalizaci\u00f3n del convenio asistieron por parte de IBEC, sus dos directores, Josep Samitier-Director Cient\u00edfico, y David Badia-Director de gesti\u00f3n, as\u00ed como la l\u00edder cient\u00edfica del proyecto, la Dra. \u00c1ranzazu Vilasante. Por parte de la Asociaci\u00f3n NEN, asisti\u00f3 su Presidente, Joaqu\u00edn Mol\u00ed, quien tambi\u00e9n rubric\u00f3 el acuerdo.<\/p>\n

La Asociaci\u00f3n NEN<\/strong><\/h2>\n

La asociaci\u00f3n NEN (Ni\u00f1os Enfermos de Neuroblastoma) agrupa a familiares de ni\u00f1os afectados que ofrecen ayuda y apoyo necesario para superar la enfermedad. El objetivo de la Asociaci\u00f3n es la de informar a los pacientes sobre los tratamientos existentes y apoyar econ\u00f3micamente la investigaci\u00f3n de esta enfermedad.<\/p>\n

Puedes encontrar m\u00e1s informaci\u00f3n y formas de ayudar a la Asociaci\u00f3n NEN, en su p\u00e1gina web oficial: http:\/\/asociacion-nen.org\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

La asociaci\u00f3n de Familiares y Amigos de Ni\u00f1os Enfermos de Neuroblastoma (NEN) e IBEC firman un acuerdo de colaboraci\u00f3n para buscar nuevos marcadores terap\u00e9uticos para este tipo de c\u00e1ncer, mediante la generaci\u00f3n de modelos basados en t\u00e9cnicas de ingenier\u00eda. El proyecto ser\u00e1 liderado por la Dra. \u00c1ranzazu Vilasante, investigadora del IBEC.<\/h3>\n","protected":false},"author":4,"featured_media":82785,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[94],"tags":[],"post_formats":[],"class_list":["post-82770","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias-institucionales"],"yoast_head":"\nIBEC y la Asociaci\u00f3n NEN a\u00fanan fuerzas contra el neuroblastoma infantil - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/es\/ibec-y-la-asociacion-nen-aunan-fuerzas-contra-el-neuroblastoma-infantil\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IBEC y la Asociaci\u00f3n NEN a\u00fanan fuerzas contra el neuroblastoma infantil - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"La asociaci\u00f3n de Familiares y Amigos de Ni\u00f1os Enfermos de Neuroblastoma (NEN) e IBEC firman un acuerdo de colaboraci\u00f3n para buscar nuevos marcadores terap\u00e9uticos para este tipo de c\u00e1ncer, mediante la generaci\u00f3n de modelos basados en t\u00e9cnicas de ingenier\u00eda. 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