Precision metabolic phenotyping has the potential to transform biomedical research and medicine by enabling early disease detection, real-time monitoring of treatment response, and personalized medicine. However, comprehensive metabolic characterization remains challenging because it often requires multiple imaging modalities and complex, time-consuming protocols.
\nIn this talk, I will present novel MRI technologies aimed at making metabolic imaging faster, more comprehensive, and accessible. I will first introduce efficient acquisition and reconstruction methods for simultaneous anatomical and metabolic imaging. I will then discuss hyperpolarized molecular probes and imaging strategies for real-time visualization of metabolism. Finally, I will present the development of low-field MRI platforms for portable, low-cost multinuclear and molecular imaging. Together, these approaches seek to bridge MR physics, molecular engineering, bioengineering, and translational imaging, establishing MRI as a versatile platform for quantitative metabolic phenotyping.<\/p>\n