{"id":13751,"date":"2015-02-16T10:43:36","date_gmt":"2015-02-16T10:43:36","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/new\/?post_type=tribe_events&#038;p=13751"},"modified":"2015-02-24T12:12:47","modified_gmt":"2015-02-24T12:12:47","slug":"ibec-seminar-gilles-subra","status":"publish","type":"tribe_events","link":"https:\/\/ibecbarcelona.eu\/es\/event\/ibec-seminar-gilles-subra\/","title":{"rendered":"IBEC Seminar: Gilles Subra"},"content":{"rendered":"<hr \/>\n<h2>Hybrid inorganic\u2013biorganic peptide materials and polymers: a bottom-up approach<\/h2>\n<p><!--more--><\/p>\n<address>Gilles Subra, Institut des Biomol\u00e9cules Max Mousseron (IBBMM), Montpellier<\/address>\n<p>The preparation of hybrid materials containing peptides relies most of the time on physical entrapment of the bioorganic moiety or on a \u2018post-grafting\u2019 procedure. In the later case, introduction of the peptide requires surface modification and ligation chemistry performed after the synthesis of the material. In contrast, we designed a new family of bioorganic-inorganic hybrid materials relying on the synthesis of hybrid peptide-trialkoxsilyl building blocks that can be engaged directly in a sol gel process requiring no extra reagents. <\/p>\n<p>This bottom-up approach permits the introduction of any type of peptide in the material, providing different functionalities, structural features, biological and physicochemical properties. The hybrid peptide block can be either grafted or introduced by direct synthesis. Several applications will be presented including the synthesis of silica multifunctional nanoparticles for imaging, peptide-catalytic mesopous materials, anti fouling glass surfaces and hydrogels. At last, the self-assembling properties of the peptide unit can be exploited to yield a range of bio-inspired nanostructured materials. <\/p>\n<p>In an effort to develop polymerization systems suitable for peptide sequences, we also describe a new class of silicone-peptides biopolymers. We used well defined chlorosilyl hybrid peptides as mononeric units, synthesized in solution or on dedicated solid support to yield linear or comb-like peptide polymers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hybrid inorganic\u2013biorganic peptide materials and polymers: a bottom-up approach<\/p>\n","protected":false},"author":4,"featured_media":0,"template":"","meta":{"_tribe_events_status":"","_tribe_events_status_reason":"","footnotes":""},"tags":[],"tribe_events_cat":[105],"class_list":["post-13751","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-ibec-seminar","cat_ibec-seminar"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IBEC Seminar: Gilles Subra - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/event\/ibec-seminar-gilles-subra\/?lang=esbactinf\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IBEC Seminar: Gilles Subra - 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