Josep Samitier Martí | Group Leader
Anna Lagunas Targarona | Senior Researcher
Mònica Mir Llorente | Senior Researcher
Maria José López Martínez | Postdoctoral Researcher
Lourdes Josefina Rivas Torcates | Postdoctoral Researcher
Romén Rodríguez Trujillo | Postdoctoral Researcher
Maider Badiola Mateos | PhD Student
Ignasi Casanellas Mercado | PhD Student
Andrea García Lizarribar | PhD Student
Roberto Paoli | PhD Student
Miriam Funes Luque | Laboratory Technician
David Izquierdo Garcia | Laboratory Technician
Sandrine Miserere | Laboratory Technician
Jennifer Maria Cruzado Rangel | Research Technician
Samuel Dulay Bacena | Research Technician
Alfonso Flores Madrid | Masters Student
Jose Marrugo Ramírez | Masters Student
Cristina Rodríguez Pereira | Visiting Researcher


The Nanobioengineering group is a multidisciplinary team working together in applying nanotechnology for the development of new biomedical systems and devices.

Nano-gap DNA sensors

The main output are diagnostic and point-of-care systems and integrated microfluidic Organ-on-Chip devices for the study of organ physiology, disease etiology, or drug screening.

The main research activities of the group include the engineering and biochemical functionalization of biomaterials integrated with microfluidics systems. The bioengineered microdevices are used to study cell responses to biomolecular compounds applied to Organ-on-Chip devices, or for the development of new lab-on-a-chip based biosensors.

Proximal segments of axons showing regeneration formation in compartmentalized microfluidic devices

The goal is to fabricate microsystems containing living cells that recapitulate tissue and organ level functions in vitro and new portable diagnosis devices that can be used as Point-of-Care systems.

The projects carried out by the group are focused on clinical and industrial problems and are related to three convergent research lines:

1. Biosensors and Lab-on-a-Chip devices for clinical diagnosis and food safety applications
– DNA sensors and platform arrays for cancer biomarker detection.
– Antibody-based sensors for pathogenic microorganisms’ detection and neurodegenerative early detection
– Sensor array for in vivo hypoxia and ischemia monitoring.
– Sensors to mimic the chemical detection of plant roots for robotic applications.
– Microfluidic chip for reagent handling in POC diagnosis devices.
– Microfluidic chip using hydrodynamic forces for cell counting and sorting.
– Application for detection of circulating tumors cells (CTC).

Fluorescence images of multi patterns fabricated with pyramidal PDMS stamp.

2. Nanotechnology applied to biomolecule interaction studies and micro/nano-environments for regenerative medicine applications
– Development of bioengineered 2D and 3D micro/nanoenvironments with a topography and chemical composition controlled at the nanoscale for cell behavior studies (adhesion, proliferation, differentiation).
– Biophysical description of cellular phenomena (cell migration, differentiation) using micro/nanotechnologies, cell biology tools and soft matter physics.
– Study of magnetite nanoparticles – Amyloid-Beta interaction in Alzheimer’s disease.

3. Microfluidic systems for biological studies and Organ-on-Chip devices
– Microfluidic chip for blood/plasma filtering.
– Spleen-on-a-chip development.
– Nanoporous-based systems for kidney-on–a-chip developments.
– Engineering microfluidic platforms for neurobiological studies.
– Development of 3D neuromuscular tissue models for soft robotics and clinical applications.


New DNA-based technique for depositing materials with a resolution of less than 10 nanometers

A study led by CSIC and involving IBEC researchers proposes a new technique using molecules ‘a la carte’ to obtain nanoscale surfaces that will have many useful applications in microelectronics and biomedicine. The work has been published in the journal Advanced Materials.

Using 3D printing to produce crucial research tools

With 3D printing set to revolutionise research, IBEC researchers have been exploring the possibilities of using the new technology to already improve their processes and methods.

Shrinking technologies to dig deeper into the body’s secrets

A team of scientists including IBEC researchers have developed a brand new technique that miniaturizes the way we study biomolecular interactions, allowing multiple analyses inside living cells for the first time.

A major step towards repairing the spinal cord

Researchers at the Institute for Bioengineering of Catalonia and their collaborators reveal that they’re a step closer to optimizing cells able to guide regeneration of the spine.

Josep Samitier selected as Spanish expert in bio- and nanotechnology for OECD

IBEC Director Josep Samitier is one of the four delegates for Spain nominated to take part in the new Working Party on Biotechnology, Nanotechnology and Converging Technologies (BNCT) of the OECD, which will start work in January 2015.

Faster and more accurate testing for causes of lower respiratory tract infections

Research and industry collaboration develops miniature diagnostic platform for respiratory infections such as pneumonia and infectious bronchitis Featured on the cover of the latest issue of Lab on a Chip

“Crean en España el primer bazo dentro de un chip capaz de actuar como este órgano humano”

The recent press release about the design of the first-ever functional 3D splenon capable of reproducing the function of the spleen, which is to filter red blood cells, by researchers from IBEC and CRESIB received lots of media coverage. Below are just a few examples.

“Càpsules de Ciència: Josep Samitier”

IBEC Director Josep Samitier stars in one of the Associació per a la Divulgació de la Cultura Cientifica (ADICC)’s ‘Càpsules de Ciència’, a series of videos highlighting biomedical and biotechnology researchers in Catalonia. In the video, he explains nanobiotechnology with the submarine on Ronda de Dalt as a backdrop, which represents the way nanodevices can travel through our bodies much like tiny submarines on a rescue mission.

Researchers and clinicians create first functional human ‘splenon-on-a-chip’

Scientists from IBEC and ISGlobal’s research centre CRESIB have designed the first-ever functional 3D splenon capable of reproducing the function of the spleen, which is to filter red blood cells.

“Nanorobots de disseny per atacar la malària”

IBEC Director and Head of Nanobioengineering, Josep Samitier, and the head of the joint IBEC/CRESIB unit on Nanomalaria, Xavier Fernández-Busquets, both featured in an article in the Catalan daily newspaper Ara this weekend.

“El hombre biónico ya no es una utopía”

IBEC appears in an article about bionics and rebuilding the human body published in Argentine daily newspaper El Tribuno (Salta), when Josep Samitier is quoted as an expert opinion on the subject.

IBEC researcher in first class of d·HEALTH Barcelona

IBEC senior researcher Mateu Pla is one of the first class of just 12 fellows chosen for the first Design Health Barcelona (d·HEALTH Barcelona) higher education programme, which starts this week.

“El futur augura que tindrem la salut a l’abast de la mà”

An interview with IBEC director Josep Samitier features in the summer edition of Alma, the magazine of the Obra Social “La Caixa”.

“Herramientas para diseñar laboratorios que caben en un chip”

In this week’s Diario Medico Special on Diagnostic Therapies, IBEC acting director Josep Samitier’s expert opinion is quoted in an article about lab-on-a-chip technologies.

A promising strategy to target malaria

A paper by the Nanobioengineering group reveals a new strategy for targeted malaria treatment that doesn’t rely on the use of expensive antibodies.

New generation robots – inspired by plants

Last week saw the start of the three-year European project PLANTOID, of which IBEC’s Nanobioengineering group is a partner, which aims to design and develop robots inspired by plants.

A journey through the technological revolution

IBEC associate director Josep Samitier officially opened the Tecnorrevolución exhibition at Barcelona’s CosmoCaixa museum last night.

“Sin un andamio de apoyo”

IBEC associate director Josep Samitier is an expert opinion quoted in El Periodico last week regarding a story about a Japanese study that succeeded in growing an embryonic eye from the stem cells of mice. He describes this first successful attempt to obtain a complex three-dimensional structure spontaneously as an important breakthrough, as it opens new avenues into coaxing the growth of cells using a method that the researchers describe as an ‘inside job’ rather than using a support structure as is usually the case.

3rd BOND Consortium Meeting at IBEC

The members of the BOND consortium met at IBEC at the beginning of last week for the 3rd technical meeting of the EU-funded international project.

Better tools for food safety

On 2 February the kick-off meeting of a transnational project coordinated by postdoc Beatriz Prieto of the Nanobioengineering group took place at IBEC. The project, ‘Development of innovative tools for Ochratoxin A’, will evaluate and tackle the threat to humans and animals of exposure to mycotoxins (fungal metabolites) in food.

Spanish Minister for Education visits Nanobioengineering group

On a tour of the Parc Científic de Barcelona (PCB) earlier this week, the Minister for Education, Ángel Gabilondo, paid a visit to IBEC’s Nanobioengineering lab and spoke at length to Associate Director Josep Samitier about his group’s research.

E-News Biocat: “Nanomedicine: Where Nanotechnology, biotechnology and the health sciences come together”

IBEC associate director Josep Samitier is a contributor to the January edition of Biocat’s e-newsletter.

El Pais: “Cuestión de límites”

“A Question of Limits” – an article written by associate director Josep Samitier to accompany a feature by El Pais journalist Mónica López Ferrado, “Los ‘nanoriesgos’ no son tan diminutos” (“‘Nanorisks’ are not so small’).

IBEC lends nanotech expertise to national exhibition

If you’ve ever wanted to move an object using the power of your mind, predict the spread of a virus and the development of a pandemic, or watch a mini robot travel through the body to deliver a drug, you need look no further than the new Tecnorevolució exhibition, which has been created with IBEC’s associate director Josep Samitier as scientific adviser.

Famous for five minutes: TV3

IBEC Project manager Juan Fran Sangüesa made the news on 22 September when he was interviewed for the midday bulletin on TV3, the Catalan television channel.

El Periódico de Catalunya: “Estamos desarrollando una nariz bioelectrónica que será capaz de diagnosticar enfermedades”

In an interview, Josep Samitier, IBEC’s associated director and group leader of Nanobioengineering research group, explains the scientific basis and the development of a bioelectronic device to detect diseases.

La Vanguardia Sunday debate section: “El reto de la nanotecnología – Aportación minúscula, mejora grande”

Josep Samitier, IBEC’s associated director and group leader of Nanobioengineering research group, analyzes the challenges and contributions of nanotechnology.

Novel Evolutionary Theory for the Explosion of Life

The Cambrian Explosion is widely regarded as one of the most relevant episodes in the history of life on Earth, when the vast majority of animal phyla first appear in the fossil record. However, the causes of its origin have been object of debate for decades and the question of what was the trigger for the single cell microorganisms Precambrian Age (500 Mio. Years ago) to assemble and organize into multicellular organisms (Metazoans) has remained unanswered until now.

Project Kick-off for a New Bioelectronic Nose

Advances in odour sensing technologies and artificial intelligence have given impetus to the use of smell in various fields, such as food safety, disease diagnosis, security, and the environment. Current electronic noses, based on electronic sensors, have considerable limitations in terms of sensitivity, reliability, and selectivity.

The Guardian Supplement: Nanotechnology 2009 – Part 2

“Ask the Experts”: In an interview, Josep Samitier, Associate Director of IBEC, talks about the potential, the impact and the contributions of nanobiotechnology.

Josep Samitier appointed Rector of the University of Barcelona

Josep Samitier, head of the IBEC nanobioengineering group, was appointed Acting Rector of the University of Barcelona (UB) on 21 April.

La recerca al Laboratori de Nanobioenginyeria de l’IBEC a El Periódico

La recerca al Laboratori de Nanobioenginyeria de l’IBEC a El Periódico El passat dilluns 14 de gener, el diari El Periódico de Catalunya, dins la secció de Societat i Ciència, destacava la actualitat i la rellevància de la recerca en cèl·lules mare per a aplicacions terapèutiques, i concretament la recerca que es porta a terme a l’IBEC, dins el grup de recerca de Micro/nanosistemes per aplicacions biomèdiques dirigit pel Prof. Josep Samitier.

The textbook Molecular Cell Biology selects a figure from a nanobioengineering researcher at IBEC

The prestigious reference textbook Molecular Cell Biology (Lodish et al.) has selected for its 6th edition (2008) a figure from the researcher at the nanobioengineering laboratory at the IBEC, Dr. Xavier Fernández-Busquets. Thanks to this important recognition of scientific excellence, the IBEC is the only Spanish institution appearing in the acknowledgements of the textbook, out of a total of 150 universitites and research centres.


EU-funded projects
PLANTOID Innovative Robotic Artefacts Inspired by Plant Roots for Soil Monitoring ICT Josep Samitier
National projects
BIOBOT Engineered biological soft robots based on neuro-muscular junction control (2015-2018) MINECO, Proyectos EXPLORA Ciencia / Tecnología 2015 Josep Samitier
Universal diagnostic platforms based on oligonucleotide cofidied nanoparticles and DNA microarray sensor devices MINECO, I+D-Investigación fundamental no orientada Josep Samitier
MINDS Plataforma MIcrofluídica 3D de cultivo Neuronal compartimentada para el estuDio de enfermedades neurológicaS (2016-2018) MINECO, Proyectos I+D Excelencia Josep Samitier
nanoET-leukemia Nanoconductance of electron transfer proteins of the respiratory chain. Direct measurementat the single molecular level and therapeutic regulation in cancer stem cells (2015-2018) MINECO, Proyectos RETOS 2015 / CIBER Josep Samitier
ISCHEMSURG Miniaturized electrochemical sensor for monitoring of free flap ischemia in post-surgery
CaixaImpulse Monica Mir
Privately funded projects
Desenvolupar un sistema d’assistència robòtica per medicina i cirurgia fetal (2016-2019) CELLEX Josep Samitier
Joint Programme_Healthy Ageing (2016) Obra Social “La Caixa” Josep Samitier
Monitoring neurocognitive deficits in Alzheimer’s and Parkinson’s diseases using saliva or blood-derived biomarkers and a multiplexed approach (2016-2018) Obra Social “La Caixa” Josep Samitier
ELECTRA-G (2014-2016) Conveni GENOMICA S.A.U. Josep Samitier
Desarrollo de una nueva tecnología lab-on-a-chip para la detección y cuantificación de secuencias de ADN/
ARN (2014-2016)
Conveni GENOMICA S.A.U. Josep Samitier


Garreta, Elena, Oria, Roger, Tarantino, Carolina, Pla-Roca, Mateu, Prado, Patricia, Fernández-Avilés, Francisco, Campistol, Josep Maria, Samitier, Josep, Montserrat, Nuria, (2017). Tissue engineering by decellularization and 3D bioprinting Materials Today , [Open Access]

Gállego, Isaac, Manning, Brendan, Prades, Joan Daniel, Mir, Mònica, Samitier, Josep, Eritja, Ramon, (2017). DNA-origami-driven lithography for patterning on gold surfaces with sub-10 nm resolution Advanced Materials 29, 1603233

Agusil, Juan Pablo, Torras, Núria, Duch, Marta, Esteve, Jaume, Pérez-García, Lluïsa, Samitier, Josep, Plaza, José A., (2017). Highly anisotropic suspended planar-array chips with multidimensional sub-micrometric biomolecular patterns Advanced Functional Materials 27, 1605912

Lagunas, Anna, Tsintzou, Iro, Vida, Yolanda, Collado, Daniel, Pérez-Inestrosa, Ezequiel, Pereira, Cristina Rodríguez, Magalhaes, Joana, Andrades, José A., Samitier, Josep, (2017). Tailoring RGD local surface density at the nanoscale toward adult stem cell chondrogenic commitment Nano Research , 1-13

Caballero, D., Samitier, J., (2017). Topological control of extracellular matrix growth: A native-like model for cell morphodynamics studies ACS Applied Materials and Interfaces 9, 4, 4159-4170

Urrea, L., Segura-Feliu, M., Masuda-Suzukake, M., Hervera, A., Pedraz, L., Aznar, J. M. G., Vila, M., Samitier, J., Torrents, E., Ferrer, I., Gavín, R., Hagesawa, M., Del Río, J. A., (2017). Involvement of cellular prion protein in Molecular Neurobiology , 1-14

Ramos, E., Pardo, W. A., Mir, M., Samitier, J., (2017). Dependence of carbon nanotubes dispersion kinetics on surfactants Nanotechnology 28, 13, 135702

Páez-Avilés, C., van Rijnsoever, F. J., Juanola-Feliu, E., Samitier, J., (2017). Multi-disciplinarity breeds diversity: the influence of innovation project characteristics on diversity creation in nanotechnology Journal of Technology Transfer , 1-24

Torras, Núria, Agusil, Juan Pablo, Vázquez, Patricia, Duch, Marta, Hernández-Pinto, Alberto M., Samitier, Josep, de la Rosa, Enrique J., Esteve, Jaume, Suárez, Teresa, Pérez-García, Lluïsa, Plaza, José A., (2016). Suspended planar-array chips for molecular multiplexing at the microscale Advanced Materials 28, 7, 1449–1454

Parra-Cabrera, C., Samitier, J., Homs-Corbera, A., (2016). Multiple biomarkers biosensor with just-in-time functionalization: Application to prostate cancer detection Biosensors and Bioelectronics 77, 1192-1200

Urrios, A., Parra-Cabrera, C., Bhattacharjee, N., Gonzalez-Suarez, A. M., Rigat-Brugarolas, L. G., Nallapatti, U., Samitier, J., Deforest, C. A., Posas, F., Garcia-Cordero, J. L., Folch, A., (2016). 3D-printing of transparent bio-microfluidic devices in PEG-DA Lab on a Chip 16, 12, 2287-2294

Caballero, D., Katuri, J., Samitier, J., Sánchez, S., (2016). Motion in microfluidic ratchets Lab on a Chip 16, 23, 4477-4481

Lagunas, A., Sasso, B., Tesson, N., Cantos, C., Martinez, E., Samitier, J., (2016). Synthesis of a polymethyl(methacrylate)-polystyrene-based diblock copolymer containing biotin for selective protein nanopatterning Polymer Chemistry 7, 212-218 [Open Access]

Credi, C., De Marco, C., Molena, E., Pla Roca, M., Samitier, J., Marques, J., Fernàndez-Busquets, X., Levi, M., Turri, S., (2016). Heparin micropatterning onto fouling-release perfluoropolyether-based polymers via photobiotin activation Colloids and Surfaces B: Biointerfaces 146, 250-259

Sanmartí-Espinal, M., Galve, R., Iavicoli, P., Persuy, M. A., Pajot-Augy, E., Marco, M. P., Samitier, J., (2016). Immunochemical strategy for quantification of G-coupled olfactory receptor proteins on natural nanovesicles Colloids and Surfaces B: Biointerfaces 139, 269-276

Tahirbegi, I.B., Pardo, W.A., Alvira, M., Mir, M., Samitier, J., (2016). Amyloid A Nanotechnology 27, 46, 465102

Silva, N., Muñoz, C., Diaz-Marcos, J., Samitier, J., Yutronic, N., Kogan, M. J., Jara, P., (2016). In situ visualization of the local photothermal effect produced on Nanoscale Research Letters 11, 180

Pla-Roca, M., Altay, G., Giralt, X., Casals, A., Samitier, J., (2016). Design and development of a microarray processing station (MPS) for automated miniaturized immunoassays Biomedical Microdevices 18, 4,

Páez-Avilés, C., Juanola-Feliu, E., Punter-Villagrasa, J., Del Moral Zamora, B., Homs-Corbera, A., Colomer-Farrarons, J., Miribel-Català , P. L., Samitier, J., (2016). Combined dielectrophoresis and impedance systems for bacteria analysis in microfluidic on-chip platforms Sensors 16, 9, 1514

Botaya, L., Coromina, X., Samitier, J., Puig-Vidal, M., Otero, J., (2016). Visualized multiprobe electrical impedance measurements with STM tips using shear force feedback control Sensors 16, 6, 757

Paoli, R., Samitier, J., (2016). Mimicking the kidney: A key role in organ-on-chip development Micromachines 7, 7, 126

Lagunas, A., Caballero, D., Samitier, J., (2016). Influence of controlled micro- and nanoengineered environments on stem cell Wiley , 85-140

Paéz Aviles, C. , Juanola-Feliu, E., Tahirbegi, I.B. , Mir, M., Gonzalez-Piñero, M., Samitier, J., (2015). Innovation and technology transfer of medical devices fosterd by cross disciplinary communities of practitioners International Journal of Innovation Management 19, 6, 1540012

Lagunas, Anna, Martinez, Elena, Samitier, Josep, (2015). Surface-bound molecular gradients for the high throughput screening of cell responses Frontiers in Bioengineering and Biotechnology 3, Article 132

Galán, T., Prieto-Simón, B., Alvira, M., Eritja, R., Götz, G., Bäuerle, P., Samitier, J., (2015). Label-free electrochemical DNA sensor using "click"-functionalized PEDOT electrodes Biosensors and Bioelectronics 74, 751-756

Reginensi, Diego, Carulla, Patricia, Nocentini, Sara, Seira, Oscar, Serra-Picamal, Xavier, Torres-Espín, Abel, Matamoros-Angles, Andreu, Gavín, Rosalina, Moreno-Flores, María Teresa, Wandosell, Francisco, Samitier, Josep, Trepat, Xavier, Navarro, Xavier, del Río, José Antonio, (2015). Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord Cellular and Molecular Life Sciences 72, 14, 2719-2737

Stanton, M. M., Samitier, J., Sánchez, S., (2015). Bioprinting of 3D hydrogels Lab on a Chip 15, 15, 3111-3115

Teller, Sara, Tahirbegi, Islam Bogachan, Mir, M., Samitier, Josep, Soriano, Jordi, (2015). Magnetite-Amyloid- Scientific Reports 5, 17261

Zaffino, R. L., Galan, T., Pardo, W. A., Mir, M., Samitier, J., (2015). Nanoprobes for enhanced electrochemical DNA sensors Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 7, 6, 817-827

Barreiros dos Santos, M., Azevedo, S., Agusil, J. P., Prieto-Simón, B., Sporer, C., Torrents, E., Juárez, A., Teixeira, V., Samitier, J., (2015). Label-free ITO-based immunosensor for the detection of very low concentrations of pathogenic bacteria Bioelectrochemistry 101, 146-152

Caballero, David, Goetz, Jacky G., (2015). Foreword: Physics of cell migration Cell Adhesion & Migration 9, 5, 325-326

Galan, Teresa, Lagunas, Anna, Martinez, Elena, Samitier, Josep, (2015). Fabrication of bioactive polypyrrole microelectrodes on insulating surfaces by surface-guided biocatalytical polymerization RSC Advances 5, 82, 67082-67088

Rigat, L., Homs-Corbera, A., Samitier, J., (2015). Highly hydrophilic microfluidic device prototyping using a novel poly(dimethylsiloxane)-based polymeric mix RSC Advances 5, 10, 7423-7425

Tong, Z., Segura-Feliu, M., Seira, O., Homs-Corbera, A., Del Río, J. A., Samitier, J., (2015). A microfluidic neuronal platform for neuron axotomy and controlled regenerative studies RSC Advances 5, 90, 73457-73466

Estévez, M., Martínez, E., Yarwood, S. J., Dalby, M. J., Samitier, J., (2015). Adhesion and migration of cells responding to microtopography Journal of Biomedical Materials Research - Part A 103, 5, 1659-1668

del Moral-Zamora, Beatriz, Punter-Villagrassa, Jaime, Oliva-Brañas, Ana M., Álvarez-Azpeitia, Juan Manuel, Colomer-Farrarons, Jordi, Samitier, Josep, Homs-Corbera, Antoni, Miribel-Català, Pere Ll, (2015). Combined dielectrophoretic and impedance system for on-chip controlled bacteria concentration: application to Escherichia coli Electrophoresis 36, 9-10, 1130-1141 [Open Access]

Del Moral Zamora, B., Álvarez Azpeitia, J.M., Oliva Brañas, A.M., Colomer-Farrarons, J., Castellarnau, M., Miribel-Català, P., Homs-Corbera, A., Juárez, A., Samitier, J., (2015). Continuous flow dielectrophoretic concentrator enhancement based on dielectric poles Electrophoresis 36, 13, 1405–1413

Jaramillo, Maria del Carmen, Huttener, Mario, Alvarez, Juan Manuel, Homs-Corbera, Antoni, Samitier, Josep, Torrents, Eduard, Juárez, Antonio, (2015). Dielectrophoresis chips improve PCR detection of the food-spoiling yeast Zygosaccharomyces rouxii in apple juice Electrophoresis 36, 13, 1471-1478

del Moral Zamora, Beatriz, Manuel Álvarez Azpeitia, Juan, Brañas, Ana Ma Oliva, Colomer-Farrarons, Jordi, Castellarnau, Marc, Miribel-Català, Pere Ll, Homs-Corbera, Antoni, Juárez, Antonio, Samitier, Josep, (2015). Dielectrophoretic concentrator enhancement based on dielectric poles for continuously flowing samples Electrophoresis 36, 13, 1405-1413

Pardo, W. A., Mir, M., Samitier, J., (2015). Signal enhancement in ultraflat electrochemical DNA biosensors Electrophoresis 36, 16, 1905-1911

de Oñate, L., Garreta, E., Tarantino, C., Martínez, E., Capilla, E., Navarro, I., Gutiérrez, J., Samitier, J., Campistol, J.M., Muñoz-Cánovas, P., Montserrat, N., (2015). Research on skeletal muscle diseases using pluripotent stem cells InTech , 333-357

Caballero, D., Samitier, J., (2014). Different strategies for the fabrication of cell culture chambers for live-cell imaging studies Chips and Tips 14, 12, 1-5

Rigat, L., Homs, A., Samitier, J., (2014). Reservoir poly(dimethylsiloxane) cap fabrication Chips and Tips 14, 10, 1-4

Rigat, L., Homs, A., Samitier, J., (2014). Simple alignment marks patterning for multilayered master fabrication Chips and Tips 14, 3, 1-7

Rigat, L., Homs, A., Samitier, J., (2014). Simple fabrication of three-dimensional ramped microstructures using SU-8 negative photoresist Chips and Tips 14, 3, 1-5

Oliva, A. M., Homs-Corbera, A., Torrents, E., Juarez, A., Samitier, J., (2014). Synergystic effect of temperature and electric field intensity in Escherichia coli inactivation Micro and Nanosystems 6, 2, 79-86

del Moral Zamora, B., Azpeitia, J. M. Á, Farrarons, J. C., Català, P. L. M., Corbera, A. H., Juárez, A., Samitier, J., (2014). Towards point-of-use dielectrophoretic methods: A new portable multiphase generator for bacteria concentration Micro and Nanosystems 6, 2, 71-78

Lagunas, A., Garcia, A., Artés, J. M., Vida, Y., Collado, D., Pérez-Inestrosa, E., Gorostiza, P., Claros, S., Andrades, J. A., Samitier, J., (2014). Large-scale dendrimer-based uneven nanopatterns for the study of local arginine-glycine-aspartic acid (RGD) density effects on cell adhesion Nano Research 7, 3, 399-409

Tahirbegi, I. B., Mir, M., Schostek, S., Schurr, M., Samitier, J., (2014). In vivo ischemia monitoring array for endoscopic surgery Biosensors and Bioelectronics 61, 124-130

Rigat, L., Elizalde-Torrent, A., Bernabeu, M., De Niz, M., Martin-Jaular, L., Fernandez-Becerra, C., Homs-Corbera, A., Samitier, J., Del Portillo, H. A., (2014). A functional microengineered model of the human splenon-on-a-chip Lab on a Chip 14, 10, 1715-1724

Van Heirstraeten, L., Spang, P., Schwind, C., Drese, K. S., Ritzi-Lehnert, M., Nieto, B., Camps, M., Landgraf, B., Guasch, F., Corbera, A. H., Samitier, J., Goossens, H., Malhotra-Kumar, S., Roeser, T., (2014). Integrated DNA and RNA extraction and purification on an automated microfluidic cassette from bacterial and viral pathogens causing community-acquired lower respiratory tract infections Lab on a Chip 14, 9, 1519-1526

Prieto-Simón, B., Samitier, J., (2014). "signal off" aptasensor based on enzyme inhibition induced by conformational switch Analytical Chemistry 86, 3, 1437-1444

Comelles, J., Caballero, D., Voituriez, ., Hortigüela, V., Wollrab, V., Godeau, A. L., Samitier, J., Martínez, E., Riveline, D., (2014). Cells as active particles in asymmetric potentials: Motility under external gradients Biophysical Journal 107, 7, 1513-1522

Tong, Z., Seira, O., Casas, C., Reginensi, D., Homs-Corbera, A., Samitier, J., Del Río, J. A., (2014). Engineering a functional neuro-muscular junction model in a chip RSC Advances 4, 97, 54788-54797

Oberhansl, S., Garcia, A., Lagunas, A., Prats-Alfonso, E., Hirtz, M., Albericio, F., Fuchs, H., Samitier, J., Martinez, E., (2014). Mesopattern of immobilised bone morphogenetic protein-2 created by microcontact printing and dip-pen nanolithography influence C2C12 cell fate RSC Advances 4, 100, 56809-56815

Garcia, A., Hortigüela, V., Lagunas, A., Cortina, C., Montserrat, N., Samitier, J., Martinez, E., (2014). Protein patterning on hydrogels by direct microcontact printing: application to cardiac differentiation RSC Advances 4, 55, 29120-29123

Zaffino, R. L., Mir, M., Samitier, J., (2014). Label-free detection of DNA hybridization and single point mutations in a nano-gap biosensor Nanotechnology 25, 10, 105501 (8)

Castillo-Fernandez, O., Rodriguez-Trujillo, R., Gomila, G., Samitier, J., (2014). High-speed counting and sizing of cells in an impedance flow microcytometer with compact electronic instrumentation Microfluidics and Nanofluidics 16, 1-2, 91-99

González, L., Otero, J., Agusil, J. P., Samitier, J., Adan, J., Mitjans, F., Puig-Vidal, M., (2014). Micropattern of antibodies imaged by shear force microscopy: Comparison between classical and jumping modes Ultramicroscopy 136, 176-184

Juanola-Feliu, E., Miribel-Català, P. L., Avilés, C. P., Colomer-Farrarons, J., González-Piñero, M., Samitier, J., (2014). Design of a customized multipurpose nano-enabled implantable system for in-vivo theranostics Sensors 14, 10, 19275-19306

Mir, M., Lugo, R., Tahirbegi, I. B., Samitier, J., (2014). Miniaturizable ion-selective arrays based on highly stable polymer membranes for biomedical applications Sensors 14, 7, 11844-11854

Tahirbegi, I. B., Alvira, M., Mir, M., Samitier, J., (2014). Simple and fast method for fabrication of endoscopic implantable sensor arrays Sensors 14, 7, 11416-11426

Oller-Moreno, S., Pardo, A., Jimenez-Soto, J. M., Samitier, J., Marco, S., (2014). Adaptive Asymmetric Least Squares baseline estimation for analytical instruments SSD 2014 Proceedings IEEE , 1569846703

Rigat, L., Elizalde, A., Del Portillo, H. A., Homs-Corbera, A., Samitier, J., (2014). Selective cell culturing step using laminar co-flow to enhance cell culture in splenon-on-a-chip biomimetic platform MicroTAS 2014 CBMS , 769-771

Oliva, A. M., Homs, A., Torrents, E., Juarez, A., Samitier, J., (2014). Effect of electric field and temperature in E.Coli viability IFMBE Proceedings Springer 41, 1833-1836

Rigat, L., Bernabeu, M., Elizalde, A., de Niz, M., Martin-Jaular, L., Fernandez-Becerra, C., Homs-Corbera, A., del Portillo, H. A., Samitier, J., (2014). Human splenon-on-a-chip: Design and validation of a microfluidic model resembling the interstitial slits and the close/fast and open/slow microcirculations IFMBE Proceedings Springer 41, 884-887

Juanola-Feliu, Esteve, Colomer-Farrarons, Jordi, Miribel-Català, Pere, González-Piñero, Manel, Samitier, Josep, (2014). Nano-enabled implantable device for glucose monitoring Wiley-VCH Verlag GmbH & Co. KGaA , 247-263

del Moral Zamora, B., Azpeitia, J. M. Á, Farrarons, J. C., Català, P. L. M., Corbera, A. H., Juárez, A., Samitier, J., (2014). Towards point-of-use dielectrophoretic methods: A new portable multiphase generator for bacteria concentration IFMBE Proceedings Springer International Publishing 41, 856-859

Valle-Delgado, J. J., Urbán, P., Fernàndez-Busquets, X., (2013). Demonstration of specific binding of heparin to Plasmodium falciparum-infected vs. non-infected red blood cells by single-molecule force spectroscopy Nanoscale 5, 9, 3673-3680

Barreiros dos Santos, M., Agusil, J. P., Prieto-Simón, B., Sporer, C., Teixeira, V., Samitier, J., (2013). Highly sensitive detection of pathogen Escherichia coli O157: H7 by electrochemical impedance spectroscopy Biosensors and Bioelectronics 45, 1, 174-180

Tahirbegi, Islam Bogachan, Mir, Monica, Samitier, Josep, (2013). Real-time monitoring of ischemia inside stomach Biosensors and Bioelectronics 40, 1, 323-328

Lagunas, A., Comelles, J., Oberhansl, S., Hortigüela, V., Martínez, E., Samitier, J., (2013). Continuous bone morphogenetic protein-2 gradients for concentration effect studies on C2C12 osteogenic fate Nanomedicine: Nanotechnology, Biology, and Medicine 9, 5, 694-701

Novo, S., Penon, O., Barrios, L., Nogués, C., Santaló, J., Durán, S., Gómez-Matínez, R., Samitier, J., Plaza, J. A., Pérez-García, L., Ibáñez, E., (2013). Direct embryo tagging and identification system by attachment of biofunctionalized polysilicon barcodes to the zona pellucida of mouse embryos Human Reproduction 28, 6, 1519-1527

Fernàndez-Busquets, X., (2013). Amyloid fibrils in neurodegenerative diseases: villains or heroes? Future Medicinal Chemistry 5, 16, 1903-1906

Fernàndez-Busquets, X., (2013). Heparin-functionalized nanocapsules: Enabling targeted delivery of antimalarial drugs Future Medicinal Chemistry 5, 7, 737-739

Caballero, D., Fumagalli, L., Teixidor, F., Samitier, J., Errachid, A., (2013). Directing polypyrrole growth by chemical micropatterns: A study of high-throughput well-ordered arrays of conductive 3D microrings Sensors and Actuators B: Chemical 177, 1003-1009

Castangia, I., Manca, M. L., Matricardi, P., Sinico, C., Lampis, S., Fernàndez-Busquets, X., Fadda, A. M., Manconi, M., (2013). Effect of diclofenac and glycol intercalation on structural assembly of phospholipid lamellar vesicles International Journal of Pharmaceutics 456, 1, 1-9

Prats-Alfonso, E., Oberhansl, S., Lagunas, A., Martínez, E., Samitier, J., Albericio, F., (2013). Effective and versatile strategy for the total solid-phase synthesis of alkanethiols for biological applications European Journal of Organic Chemistry 2013, 7, 1233-1239

Rodriguez-Segui, Santiago A., Ortuno, Maria Jose, Ventura, Francesc, Martinez, Elena, Samitier, Josep, (2013). Simplified microenvironments and reduced cell culture size influence the cell differentiation outcome in cellular microarrays Journal of Materials Science: Materials in Medicine 24, 1, 189-198

Diéguez, Lorena, Caballero, David, Calderer, Josep, Moreno, Mauricio, Martínez, Elena, Samitier, Josep, (2012). Optical gratings coated with thin Si3N4 layer for efficient immunosensing by optical waveguide lightmode spectroscopy Biosensors 2, 2, 114-126

Oberhansl, Sabine, Hirtz, Michael, Lagunas, Anna, Eritja, Ramon, Martinez, Elena, Fuchs, Harald, Samitier, Josep, (2012). Facile modification of silica substrates provides a platform for direct-writing surface click chemistry Small 8, 4, 541-545

Lagunas, Anna , Comelles, Jordi, Martínez, Elena, Prats-Alfonso, Elisabet , Acosta, Gerardo A., Albericio, Fernando , Samitier, Josep , (2012). Cell adhesion and focal contact formation on linear RGD molecular gradients: study of non-linear concentration dependence effects Nanomedicine: Nanotechnology, Biology and Medicine 8, 4, 432-439

Mir, Mònica , Tahirbegi, Islam Bogachan , Valle-Delgado, Juan José , Fernàndez-Busquets, X., Samitier, Josep , (2012). In vitro study of magnetite-amyloid Nanomedicine: Nanotechnology, Biology and Medicine 8, 6, 974-980

Esquivel, Juan Pablo , Castellarnau, Marc , Senn, Tobias , Löchel, Bernd , Samitier, Josep , Sabaté, Neus , (2012). Fuel cell-powered microfluidic platform for lab-on-a-chip applications Lab on a Chip 12, 1, 74-79

Esquivel, J. P., Colomer-Farrarons, J., Castellarnau, M., Salleras, M., del Campo, F. J., Samitier, J., Miribel-Catala, P., Sabate, N., (2012). Fuel cell-powered microfluidic platform for lab-on-a-chip applications: Integration into an autonomous amperometric sensing device Lab on a Chip 12, 21, 4232-4235

Parra-Cabrera, C., Sporer, C., Rodriguez-Villareal, I., Rodriguez-Trujillo, R., Homs-Corbera, A., Samitier, J., (2012). Selective in situ functionalization of biosensors on LOC devices using laminar co-flow Lab on a Chip 12, 20, 4143-4150

Yang, Cheng, Lates, Vasilica, Prieto-Simón, Beatriz, Marty, Jean-Louis, Yang, Xiurong, (2012). Aptamer-DNAzyme hairpins for biosensing of Ochratoxin A Biosensors and Bioelectronics 32, 1, 208-212

Penon, O., Novo, S., Duran, S., Ibanez, E., Nogues, C., Samitier, J., Duch, M., Plaza, J. A., Perez-Garcia, L., (2012). Efficient biofunctionalization of polysilicon barcodes for adhesion to the zona pellucida of mouse embryos Bioconjugate Chemistry 23, 12, 2392-2402

Tort, N., Salvador, J. P., Avino, A., Eritja, R., Comelles, J., Martinez, E., Samitier, J., Marco, M. P., (2012). Synthesis of steroid-oligonucleotide conjugates for a DNA site-encoded SPR immunosensor Bioconjugate Chemistry 23, 11, 2183-2191

Caballero, D., Martinez, E., Bausells, J., Errachid, A., Samitier, J., (2012). Impedimetric immunosensor for human serum albumin detection on a direct aldehyde-functionalized silicon nitride surface Analytica Chimica Acta 720, 43-48

Comelles, J., Hortigüela, V., Samitier, J., Martinez, E., (2012). Versatile gradients of covalently bound proteins on microstructured substrates Langmuir 28, 38, 13688-13697

Campas, Monica, Garibo, Diana, Prieto-Simon, Beatriz, (2012). Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins Analyst 137, 5, 1055-1067

Calò, A., Sanmartí-Espinal, M., Iavicoli, P., Persuy, M. A., Pajot-Augy, E., Gomila, G., Samitier, J., (2012). Diffusion-controlled deposition of natural nanovesicles containing G-protein coupled receptors for biosensing platforms Soft Matter 8, 46, 11632-11643

Valle-Delgado, J. J., Liepina, I., Lapidus, D., Sabaté, R., Ventura, S., Samitier, J., Fernàndez-Busquets, X., (2012). Self-assembly of human amylin-derived peptides studied by atomic force microscopy and single molecule force spectroscopy Soft Matter 8, 4, 1234-1242

Villar-Pique, A., De Groot, N. S., Sabaté, R., Acebrón, S. P., Celaya, G., Fernàndez-Busquets, X., Muga, A., Ventura, S., (2012). The effect of amyloidogenic peptides on bacterial aging correlates with their intrinsic aggregation propensity Journal of Molecular Biology 421, 2-3, 270-281

Urban, P., Valle-Delgado, J. J., Moles, E., Marques, J., Diez, C., Fernàndez-Busquets, X., (2012). Nanotools for the delivery of antimicrobial peptides Current Drug Targets 13, 9, 1158-1172

Baccar, Z.M., Caballero, D., Eritja, R., Errachid, A., (2012). Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences Electrochimica Acta 74, 123-129

Kuphal, M., Mills, C.A., Korri-Youssoufi, H., Samitier, J., (2012). Polymer-based technology platform for robust electrochemical sensing using gold microelectrodes Sensors and Actuators B: Chemical 161, 1, 279-284

Rosa Hernández, M., Urbán, P., Casals, E., Estelrich, J., Escolar, G., Galán, A. M., (2012). Liposomes bearing fibrinogen could potentially interfere with platelet interaction and procoagulant activity International Journal of Nanomedicine 7, 2339-2347

Juanola-Feliu, E., Colomer-Farrarons, J., Miribel-Català , P., Samitier, J., Valls-Pasola, J., (2012). Market challenges facing academic research in commercializing nano-enabled implantable devices for in-vivo biomedical analysis Technovation 32, 3-4, 193-204

Veeregowda, D. H., van der Mei, H. C., de Vries, J., Rutland, M. W., Valle-Delgado, J. J., Sharma, P. K., Busscher, H. J., (2012). Boundary lubrication by brushed salivary conditioning films and their degree of glycosylation Clinical Oral Investigations 16, 5, 1499-1506

Gallach, D., Torres-Costa, V., García-Pelayo, L., Climent-Font, A., Martín-Palma, R. J., Barreiros-Das-Santos, M., Sporer, C., Samitier, J., Manso, M., (2012). Properties of bilayer contacts to porous silicon Applied Physics A: Materials Science and Processing 107, 2, 293-300

Azevedo, S., Diéguez, L., Carvalho, P., Carneiro, J. O., Teixeira, V., Martínez, E., Samitier, J., (2012). Deposition of ITO thin films onto PMMA substrates for waveguide based biosensing devices Journal of Nano Research 17, 75-83

Colomer-Farrarons, J., Miribel-Català , P., Juanola-Feliu, E., Samitier, J., (2012). A proof-of-concept of a multi-harvesting power source in a low-voltage CMOS technology IEEE Computer Society IEEE , 655-659

Valle-Delgado, J. J., Molina-Bolívar, J. A., Galisteo-González, F., Gálvez-Ruiz, M. J., (2011). Evidence of hydration forces between proteins Current Opinion in Colloid and Interface Science 16, 6, 572-578

Urban, Patricia, Estelrich, Joan, Cortés, Alfred, Fernàndez-Busquets, X., (2011). A nanovector with complete discrimination for targeted delivery to Plasmodium falciparum-infected versus non-infected red blood cells in vitro Journal of Controlled Release 151, 2, 202-211

Ivon Rodriguez-Villarreal, Angeles, Tarn, Mark D., Madden, Leigh A., Lutz, Julia B., Greenman, John, Samitier, Josep, Pamme, Nicole, (2011). Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup Lab on a Chip 11, 7, 1240-1248

Sánchez-Martín, M. J., Urbán, P., Pujol, M., Haro, I., Alsina, M. A., Busquets, M. A., (2011). Biophysical investigations of GBV-C E1 peptides as potential inhibitors of HIV-1 fusion peptide ChemPhysChem 12, 15, 2816-2822

Castillo-Fernandez, Oscar, Salieb-Beugelaar, Georgette B., van Nieuwkasteele, Jan W., Bomer, Johan G., Arundell, Martin, Samitier, Josep, van den Berg, Albert, Eijkel, Jan C. T., (2011). Electrokinetic DNA transport in 20 nm-high nanoslits: Evidence for movement through a wall-adsorbed polymer nanogel Electrophoresis 32, 18, 2402-2409

Mir, Monica, Martinez-Rodriguez, Sergio, Castillo-Fernandez, Oscar, Homs-Corbera, Antoni, Samitier, Josep, (2011). Electrokinetic techniques applied to electrochemical DNA biosensors Electrophoresis 32, 8, 811-821

Urban, Patricia, Estelrich, Joan, Adeva, Alberto, Cortes, Alfred, Fernàndez-Busquets, X., (2011). Study of the efficacy of antimalarial drugs delivered inside targeted immunoliposomal nanovectors Nanoscale Research Letters 6, 1, 620

Barthelmebs, L., Jonca, J., Hayat, A., Prieto-Simon, B., Marty, J. L., (2011). Enzyme-Linked Aptamer Assays (ELAAs), based on a competition format for a rapid and sensitive detection of Ochratoxin A in wine Food Control 22, 5, 737-743

Rodriguez-Segui, Santiago A., Pons Ximenez, Jose Ignacio, Sevilla, Lidia, Ruiz, Ana, Colpo, Pascal, Rossi, Francois, Martinez, Elena, Samitier, Josep, (2011). Quantification of protein immobilization on substrates for cellular microarray applications Journal of Biomedical Materials Research - Part A 98A, 2, 245-256

Fernandez, Javier G., Samitier, Josep, Mills, Christopher A., (2011). Simultaneous biochemical and topographical patterning on curved surfaces using biocompatible sacrificial molds Journal of Biomedical Materials Research - Part A 98A, 2, 229-234

Tahirbegi, I. B., Mir, M., (2011). Slit-wave model for band structures in solid state physics Modern Physics Letters B 25, 3, 151-161

Juanola-Feliu, E., Colomer-Farrarons, J., Miribel-Catala, P., Samitier, J., Valls-Pasola, J., (2011). Challenges facing academic research in commercializing event-detector implantable devices for an in-vivo biomedical subcutaneous device for biomedical analysis Proceedings of the SPIE - The International Society for Optical Engineering SPIE - The International Society for Optical Engineering, USA 8067, 80670P

del Moral Zamora, B., Colomer, J., Mir, M., Homs, A., Miribel, P., Samitier, J., (2011). Combined impedance and dielectrophoresis portable device for point-of-care analysis Proceedings SPIE SPIE 8068, 80680T (19)

Punter-Villagrasa, J., Colomer-Farrarons, J., Miribel-Catala, P., Puig-Vidal, M., Samitier, J., (2011). Discrete to full custom ASIC solutions for bioelectronic applications Proceedings of the SPIE - The International Society for Optical Engineering SPIE - The International Society for Optical Engineering 8067, 80670Q

Colomer-Farrarons, Jordi , Miribel-Català, Pedro Luís, Samitier, Josep , (2011). Low-voltage µpower CMOS subcutaneous biomedical implantable device for true/false applications Biomedical Engineering ACTA Press Biomedical Engineering, 424-428

Mir, M., (2011). Aptamers: The new biorecognition element for proteomic biosensing Nova Science Publishers, Inc , -----

Colomer-Farrarons, Jordi, Miribel-Català, Pere LI., Rodríguez-Villarreal, A. Ivón, Samitier, Josep, (2011). Portable bio-devices: Design of electrochemical instruments from miniaturized to implantable devices InTech Biomedical Engineering, 373-400

Martinez, Elena, Samitier, Josep, (2011). Soft lithography and variants Wiley-VCH Verlag GmbH&Co , 57-66

Prieto-Simón, B., Campà s, M., Marty, J. L., (2010). Electrochemical aptamer-based sensors Bioanalytical Reviews 1, 2, 141-157

Valle-Delgado, J. J., Alfonso-Prieto, M., de Groot, N. S., Ventura, S., Samitier, J., Rovira, C., Fernàndez-Busquets, X., (2010). Modulation of A beta(42) fibrillogenesis by glycosaminoglycan structure FASEB Journal 24, 11, 4250-4261

Sisquella, X., de Pourcq, K., Alguacil, J., Robles, J., Sanz, F., Anselmetti, D., Imperial, S., Fernàndez-Busquets, X., (2010). A single-molecule force spectroscopy nanosensor for the identification of new antibiotics and antimalarials FASEB Journal 24, 11, 4203-4217

Rodriguez-Villarreal, A. I., Arundell, M., Carmona, M., Samitier, J., (2010). High flow rate microfluidic device for blood plasma separation using a range of temperatures Lab on a Chip 10, 2, 211-219

Valente, T., Gella, A., Fernàndez-Busquets, X., Unzeta, M., Durany, N., (2010). Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus Neurobiology of Disease 37, 1, 67-76

Fernàndez-Busquets, X., Ponce, J., Bravo, R., Arimon, M., Martianez, T., Gella, A., Cladera, J., Durany, N., (2010). Modulation of amyloid beta peptide(1-42) cytotoxicity and aggregation in vitro by glucose and chondroitin sulfate Current Alzheimer Research 7, 5, 428-438

Comelles, J., Estevez, M., Martinez, E., Samitier, J., (2010). The role of surface energy of technical polymers in serum protein adsorption and MG-63 cells adhesion Nanomedicine: Nanotechnology Biology and Medicine 6, 1, 44-51

Estevez, M., Fernandez-Ulibarri, I., Martinez, E., Egea, G., Samitier, J., (2010). Changes in the internal organization of the cell by microstructured substrates Soft Matter 6, 3, 582-590

Lagunas, A., Comelles, J., Martinez, E., Samitier, J., (2010). Universal chemical gradient platforms using poly(methyl methacrylate) based on the biotin streptavidin interaction for biological applications Langmuir 26, 17, 14154-14161

Gallego, I., Oncins, G., Sisquella, X., Fernàndez-Busquets, X., Daban, J. R., (2010). Nanotribology results show that DNA forms a mechanically resistant 2D network in metaphase chromatin plates Biophysical Journal 99, 12, 3951-3958

Harder, A., Walhorn, V., Dierks, T., Fernàndez-Busquets, X., Anselmetti, D., (2010). Single-molecule force spectroscopy of cartilage aggrecan self-adhesion Biophysical Journal 99, 10, 3498-3504

Sabaté, R., Espargaró, A., de Groot, N. S., Valle-Delgado, J. J., Fernàndez-Busquets, X., Ventura, S., (2010). The role of protein sequence and amino acid composition in amyloid formation: Scrambling and backward reading of IAPP amyloid fibrils Journal of Molecular Biology 404, 2, 337-352

Darwish-, N., Caballero, D., Moreno, M., Errachid, A., Samitier, J., (2010). Multi-analytic grating coupler biosensor for differential binding analysis Sensors and Actuators B: Chemical 144, 2, 413-417

de Oliveira, I. A. M., Vocanson, F., Uttaro, J. P., Asfari, Z., Mills, C. A., Samitier, J., Errachid, A., (2010). Characterization of a self-assembled monolayer based on a calix[4]crown-5 derivate: fabrication of a chemical sensor sensitive to calcium Journal of Nanoscience and Nanotechnology 10, 1, 413-420

Caballero, D., Villanueva, G., Plaza, J. A., Mills, C. A., Samitier, J., Errachid, A., (2010). Sharp high-aspect-ratio AFM tips fabricated by a combination of deep reactive ion etching and focused ion beam techniques Journal of Nanoscience and Nanotechnology 10, 1, 497-501

Sanmarti, M., Iavicoli, P., Pajot-Augy, E., Gomila, G., Samitier, J., (2010). Human olfactory receptors immobilization on a mixed self assembled monolayer for the development of a bioelectronic nose Procedia Engineering (EUROSENSOR XXIV CONFERENCE) Elsevier Science 5, 786-789

Illa, X., Rodriguez-Trujillo, R., Ordeig, O., De Malsche, W., Homs-Corbera, A., Gardeniers, H., Desmet, G., Kutter, J. P., Samitier, J., Romano-Rodríguez, A., (2010). Simultaneous impedance and fluorescence detection of proteins in a cyclo olefin polymer chip containing a column with an ordered pillar array with integrated gold microelectrodes MicroTAS 2010 UoG 2, 1280-1282

Fernàndez-Busquets, X., Körnig, A., Bucior, I., Burger, M. M., Anselmetti, D., (2009). Self-recognition and Ca2+-dependent carbohydrate-carbohydrate cell adhesion provide clues to the cambrian explosion Molecular Biology and Evolution 26, 11, 2551-2561

Guix, F. X., Ill-Raga, G., Bravo, R., Nakaya, T., de Fabritiis, G., Coma, M., Miscione, G. P., Villa-Freixa, J., Suzuki, T., Fernàndez-Busquets, X., Valverde, M. A., de Strooper, B., Munoz, F. J., (2009). Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation Brain 132, 5, 1335-1345

Tort, N., Salvador, J. P., Eritja, R., Poch, M., Martinez, E., Samitier, J., Marco, M. P., (2009). Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids Trac-Trends in Analytical Chemistry 28, 6, 718-728

Fernandez, J. G., Mills, C. A., Samitier, J., (2009). Complex microstructured 3D surfaces using chitosan biopolymer Small 5, 5, 614-620

Caballero, D., Samitier, J., Bausells, J., Errachid, A., (2009). Direct patterning of anti-human serum albumin antibodies on aldehyde-terminated silicon nitride surfaces for HSA protein detection Small 5, 13, 1531-1534

Ruiz, A., Mills, C. A., Valsesia, A., Martinez, E., Ceccone, G., Samitier, J., Colpo, P., Rossi, F., (2009). Large-area, nanoimprint-assisted microcontact stripping for the fabrication of microarrays of fouling/nonfouling nanostructures Small 5, 10, 1133-1137

Pla, D., Sischka, A., Albericio, F., Alvarez, M., Fernàndez-Busquets, X., Anselmetti, D., (2009). Optical-tweezers study of topoisomerase inhibition Small 5, 11, 1269-1272

Martinez, E., Lagunas, A., Mills, C. A., Rodriguez-Segui, S., Estevez, M., Oberhansl, S., Comelles, J., Samitier, J., (2009). Stem cell differentiation by functionalized micro- and nanostructured surfaces Nanomedicine 4, 1, 65-82

Hosta, L., Pla, M., Arbiol, J., Lopez-Iglesias, C., Samitier, J., Cruz, L. J., Kogan, M. J., Albericio, F., (2009). Conjugation of Kahalalide F with gold nanoparticles to enhance in vitro antitumoral activity Bioconjugate Chemistry 20, 1, 138-146

Mir, M., Cameron, P. J., Zhong, X., Azzaroni, O., Alvarez, M., Knoll, W., (2009). Anti-fouling characteristics of surface-confined oligonucleotide strands bioconjugated on streptavidin platforms in the presence of nanomaterials Talanta 78, 3, 1102-6

Mir, M., Homs, A., Samitier, J., (2009). Integrated electrochemical DNA biosensors for lab-on-a-chip devices Electrophoresis 30, 19, 3386-3397

Gimenez-Oya, V., Villacanas, O., Fernàndez-Busquets, X., Rubio-Martinez, J., Imperial, S., (2009). Mimicking direct protein-protein and solvent-mediated interactions in the CDP-methylerythritol kinase homodimer: a pharmacophore-directed virtual screening approach Journal of Molecular Modeling 15, 8, 997-1007

Lopez-Martinez, M. J., Campo, E. M., Caballero, D., Fernandez, E., Errachid, A., Esteve, J., Plaza, J. A., (2009). Versatile micropipette technology based on deep reactive ion etching and anodic bonding for biological applications Journal of Micromechanics and Microengineering 19, 10, 105013 (10 pp.)

Rodriguez-Segui, S. A., Pla, M., Engel, E., Planell, J. A., Martinez, E., Samitier, J., (2009). Influence of fabrication parameters in cellular microarrays for stem cell studies Journal of Materials Science: Materials in Medicine 20, 7, 1525-1533

Caballero, D., Samitier, J., Errachid, A., (2009). Submerged nanocontact printing (SnCP) of thiols Journal of Nanoscience and Nanotechnology 9, 11, 6478-6482

Merolli, A., Rocchi, L., Catalano, F., Planell, J., Engel, E., Martinez, E., Sbernardori, M. C., Marceddu, S., Leali, P. T., (2009). In vivo regeneration of rat sciatic nerve in a double-halved stitch-less guide: a pilot-study Microsurgery 29, 4, 310-318

Martinez, E., Engel, E., Planell, J. A., Samitier, J., (2009). Effects of artificial micro- and nano-structured surfaces on cell behaviour Annals of Anatomy-Anatomischer Anzeiger 191, 1, 126-135

Engel, E., Martinez, E., Mills, C. A., Funes, M., Planell, J. A., Samitier, J., (2009). Mesenchymal stem cell differentiation on microstructured poly (methyl methacrylate) substrates Annals of Anatomy-Anatomischer Anzeiger 191, 1, 136-144

Gustavsson, J., Zine, N., Vocanson, F., Engel, E., Planell, J., Bausells, J., Samitier, J., Errachid, A., (2009). Characterization of potassium-selective field effect transistors based on 1,3-(di-4-oxabutanol)-calix[4]arene-crown-5 as ionophore Sensor Letters 7, 5, 795-800

Colomer-Farrarons, J., Miribel-Catala , P., Saiz-Vela, A., Samitier, J., (2009). A 60 uW low-power low-voltage power management unit for a self-powered system based on low-cost piezoelectric powering generators Proceedings of the 35th European Solid-State Circuits Conference. ESSCIRC 2009 IEEE , 280-283

Colomer-Farrarons, J., Miribel-Catala , P., Rodriguez, I., Samitier, J., (2009). CMOS front-end architecture for in-vivo biomedical implantable devices 35th Annual Conference of IEEE Industrial Electronics (IECON 2009) IEEE , 4401-4408

Colomer-Farrarons, J., Miribel-Catala, P. L., Samitier, J., Arundell, M., Rodriguez, I., (2009). Design of a miniaturized electrochemical instrument for in-situ O/sub 2/ monitoring Sensors and Signal Conditioning SPIE 7363, 73630A

Barreiros dos Santos, M., Sporer, C., Sanvicens, N., Pascual, N., Errachid, A., Martinez, E., Marco, M. P., Teixeira, V., Samiter, J., (2009). Detection of pathogenic Bacteria by Electrochemical Impedance Spectroscopy: Influence of the immobilization strategies on the sensor performance Procedia Chemistry Elsevier Science, BV 1, 1291-1294

Colomer, J., Miribel-Catala , P., Saiz-Vela, A., Rodriguez, I., Samitier, J., (2009). A low power CMOS biopotentiostat in a low-voltage 0.13 um digital technology 52nd IEEE International Midwest Symposium on Circuits and Systems (MWSCAS) IEEE , 172-175

Rodriguez-Segui, S. A., Bucior, I., Burger, M. M., Errachid, A., Fernàndez-Busquets, X., (2009). Application of the quartz crystal microbalance to the study of multivalent carbohydrate-carbohydrate adhesion Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 782-787

Zazoua, A., Kherrat, R., Caballero, D., Errachid, A., Jaffrezic-Renault, N., Bessueille, F., Leonard, D., (2009). Characterisation of a Cr(VI) sensitive polysiloxane membrane by x-ray photoelectron spectrometry and atomic force microscopy Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 995-1000

Baccar, Z. M., Caballero, D., Zine, N., Jaffrezic-Renault, N., Errachid, A., (2009). Development of urease/layered double hydroxides nanohybrid materials for the urea detection: Synthesis, analytical and catalytic characterizations Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 676-682

Diaguez, L., Darwish-, N., Mir, M., Martinez, E., Moreno, M., Samitier, J., (2009). Effect of the refractive index of buffer solutions in evanescent optical biosensors Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 851-855

Guaus, E., Torrent-Burgues, J., Zine, N., Errachid, A., (2009). Glassy carbon electrode modified with a langmuir-blodgett film of a thiomacrocyclic ionophore for Cu(II) recognition Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 1006-1011

Sporer, C., Casal, L., Caballero, D., Samitier, J., Errachid, A., Perez-Garcia, L., (2009). Novel anionophores for biosensor applications: nano characterisation of SAMS based on amphiphilic imidazolium protophanes and cyclophanes on gold surfaces Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 757-764

Baccar, Z. M., Hidouri, S., El Bari, N., Jaffrezic-Renault, N., Errachid, A., Zine, N., (2009). Stable immobilization of anti-beta casein antibody onto layered double hydroxides materials for biosensor applications Sensor Letters AMER SCIENTIFIC PUBLISHERS 7, 5, 647-655

Zazoua, A., Morakchi, K., Kherrat, R., Samar, M. H., Errachid, A., Jaffrezic-Renault, N., Boubellout, R., (2008). Electrochemical characterization of an EIS sensor functionalized with a TOPO doped polymeric layer for Cr(VI) detection IRBM 29, 2-3, 187-191

Bravo, R., Arimon, M., Valle-Delgado, J. J., Garcia, R., Durany, N., Castel, S., Cruz, M., Ventura, S., Fernàndez-Busquets, X., (2008). Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity Journal of Biological Chemistry 283, 47, 32471-32483

Rodriguez-Trujillo, R., Castillo-Fernandez, O., Garrido, M., Arundell, M., Valencia, A., Gomila, G., (2008). High-speed particle detection in a micro-Coulter counter with two-dimensional adjustable aperture Biosensors and Bioelectronics 24, 2, 290-296

Morell, M., Bravo, R., Espargaro, A., Sisquella, X., Aviles, F. X., Fernàndez-Busquets, X., Ventura, S., (2008). Inclusion bodies: Specificity in their aggregation process and amyloid-like structure Biochimica et Biophysica Acta - Molecular Cell Research 1783, 10, 1815-1825

Roca-Cusachs, P., Alcaraz, J., Sunyer, R., Samitier, J., Farre, R., Navajas, D., (2008). Micropatterning of single endothelial cell shape reveals a tight coupling between nuclear volume in G1 and proliferation Biophysical Journal 94, 12, 4984-4995

Embrechts, A., Feng, C. L., Mills, C. A., Lee, M., Bredebusch, I., Schnekenburger, J., Domschke, W., Vancso, G. J., Schönherr, H., (2008). Inverted microcontact printing on polystyrene-block-poly(tert-butyl acrylate) films: A versatile approach to fabricate structured biointerfaces across the length scales Langmuir 24, 16, 8841-8849

Issle, J., Pla, M., Martínez, E., Hartmann, U., (2008). Patterning of magnetic nanobeads on surfaces by poly(dimethylsiloxane) stamps Langmuir 24, 3, 888-893

de Oliveira, I. A. M., Risco, D., Vocanson, F., Crespo, E., Teixidor, F., Zine, N., Bausells, J., Samitier, J., Errachid, A., (2008). Sodium ion sensitive microelectrode based on a p-tert-butylcalix[4]arene ethyl ester Sensors and Actuators B: Chemical 130, 1, 295-299

Fernandez, J. G., Mills, C. A., Martinez, E., Lopez-Bosque, M. J., Sisquella, X., Errachid, A., Samitier, J., (2008). Micro- and nanostructuring of freestanding, biodegradable, thin sheets of chitosan via soft lithography Journal of Biomedical Materials Research - Part A 85A, 1, 242-247

Guaus, E., Errachid, A., Torrent-Burgues, J., (2008). Voltammetric response of a glassy carbon electrode modified by a Langmuir-Blodgett film of a thiomacrocyclic compound Journal of Electroanalytical Chemistry 614, 1-2, 73-82

Lopez, M. J., Caballero, D., Campo, E. M., Perez-Castillejos, R., Errachid, A., Esteve, J., Plaza, J. A., (2008). Focused ion beam-assisted technology in sub-picolitre micro-dispenser fabrication Journal of Micromechanics and Microengineering 18, 7, 8

Cho, S., Castellarnau, M., Samitier, J., Thielecke, H., (2008). Dependence of impedance of embedded single cells on cellular behaviour Sensors 8, 2, 1198-1211

Martinez, E., Engel, E., Lopez-Iglesias, C., Mills, C. A., Planell, J. A., Samitier, J., (2008). Focused ion beam/scanning electron microscopy characterization of cell behavior on polymer micro-/nanopatterned substrates: A study of cell-substrate interactions Micron 39, 2, 111-116

Mills, C. A., Fernandez, J. G., Errachid, A., Samitier, J., (2008). The use of high glass temperature polymers in the production of transparent, structured surfaces using nanoimprint lithography Microelectronic Engineering 85, 9, 1897-1901

Gustavsson, J., Altankov, G., Errachid, A., Samitier, J., Planell, J. A., Engel, E., (2008). Surface modifications of silicon nitride for cellular biosensor applications Journal of Materials Science-Materials in Medicine 19, 4, 1839-1850

Renault, N. J., Korri-Youssoufi, H., Kyselovik, J., Auger, V., Errachid, A., Mills, C. A., Strohhöfer, C., Ali, Z., (2008). Impedimetric microanalysis system for deep vein thrombosis point-of-care testing EMBS'08 - "Personalized Healthcare through Technology" IEEE , 1856

Rodriguez-Trujillo, R., Castillo-Fernandez, O., Arundell, M., Samitier, J., Gomila, G., (2008). Yeast cells detection in a very fast and highly versatile microfabricated cytometer MicroTAS 2008 Chemical and Biological Microsystems Society , 1888-1890

Zazoua, A., Kherrat, R., Samar, M. H., Errachid, A., Jaffrezic-Renault, N., Bessueille, F., Leonard, D., (2008). Characterization of TBP containing polysiloxane membrane/insulator/semiconductor structures for hexavalent chromium detection Materials Science and Engineering: C-Biomimetic and Supramolecular Systems Elsevier Science BV 28, 5-6, 1014-1019

Errachid, A., Mills, C. A., Pla, M., Lopez, M. J., Villanueva, G., Bausells, J., Crespo, E., Teixidor, F., Samitier, J., (2008). Focused ion beam production of nanoelectrode arrays Materials Science & Engineering C Elsevier Science 28, 5-6, 777-780

Casuso, I., Pla, M., Gomila, G., Samitier, J., Minic, J., Persuy, M. A., Salesse, R., Pajot-Augy, E., (2008). Immobilization of olfactory receptors onto gold electrodes for electrical biosensor Materials Science & Engineering C Elsevier Science 28, 5-6, 686-691

Castellarnau, M., Zine, N., Bausells, J., Madrid, C., Juarez, A., Samitier, J., Errachid, A., (2008). ISFET-based biosensor to monitor sugar metabolism in bacteria Materials Science & Engineering C Elsevier Science 28, 5-6, 680-685

Barhoumi, H., Haddad, R., Maaref, A., Bausells, J., Bessueille, F., Leonard, D., Jaffrezic-Renault, N., Martelet, C., Zine, N., Errachid, A., (2008). Na+-implanted membrane for a capacitive sodium electrolyte-Insulator-Semiconductor microsensors Sensor Letters Amer Scientific Publishers 6, 1, 204-208

Sabella, C., Faszewski, E., Himic, L., Colpitts, K. M., Kaltenbach, J., Burger, M. M., Fernàndez-Busquets, X., (2007). Cyclosporin A suspends transplantation reactions in the marine sponge Microciona prolifera Journal of Immunology 179, 9, 5927-5935

Pla, M., Fernandez, J. G., Mills, C. A., Martinez, E., Samitier, J., (2007). Micro/nanopatterning of proteins via contact printing using high aspect ratio PMMA stamps and NanoImprint apparatus Langmuir 23, 16, 8614-8618

Mills, C. A., Pla, M., Martin, C., Lee, M., Kuphal, M., Sisquella, X., Martinez, E., Errachid, A., Samitier, J., (2007). Structured thin organic active layers and their use in electrochemical biosensors Measurement & Control 40, 3, 88-91

Rodriguez, Segui, Bucior, I., Burger, M. M., Samitier, J., Errachid, A., Fernàndez-Busquets, X., (2007). Application of a bio-QCM to study carbohydrates self-interaction in presence of calcium Transducers '07 & Eurosensors Xxi, Digest of Technical Papers IEEE 1-2, 1995-1998

Jbari, A., Bellarbi, L., Zine, N., Mills, C. A., Samitier, J., Errachid, A., (2007). Multiplexed frequency spectrum analyzer instrumentation for the characterization of multiple QCM-based biosensors C3 - 2007 SENSORCOMM 2007 IEEE , 436-440

McMurray, A. A., Ali, Z., Kyselovik, J., Mills, C. A., Renault, N. J., Santha, H., Strohhöfer, C., (2007). A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood EMBS 2007 IEEE , 115-118

Castellarnau, Marc, Errachid, Abdelhamid, Madrid, Cristina, Juárez, Antonio, Samitier, Josep, (2006). Dielectrophoresis as a tool to characterize and differentiate isogenic mutants of Escherichia coli Biophysical Journal 91, 10, 3937-3945

Muñoz, Luis Miguel, Casals, Alícia, Amat, Josep, Puig-Vidal, Manel, Samitier, Josep, (2005). Improved AFM scanning methodology with adaptation to the target shape C3 - Proceedings - IEEE International Conference on Robotics and Automation ICRA 2005 IEEE , 1529-1534


Nanofabrication and nanomanipulation

  • Automatized microcontact printing system (custom-made)
  • 3D Printing system for microfluidic devices.


  • Surface Plasmon Resonance (SPR)
  • Potentiostates
  • Optical Waveguide Lightmode Spectroscope (OWLS)
  • Atomic Force Microscope (AFM)
  • Optical Microscopes (white light/epifluorescence)
  • Electrical Impedance spectroscopy (EIS)
  • Multi-frequency Lock-in Amplifier
  • Sub-femtoamp Remote SourceMeter Instrument

Molecular/cell biology

  • Biological safety cabinet (class II)
  • Microwell plate readers
  • Protein and DNA electrophoresis systems
  • Microincubator Okolab
  • Nanodrop spectrophotometer
  • CO2 incubator for cells
  • Cell culture cabin


  • High precision syringe pumps
  • Peristaltic pumps


  • Prof. Fernando Albericio
    Institut de Recerca Biomédica (IRB), Barcelona, Spain
  • Dr. José Antonio Andrades
    Universidad de Málaga, Spain
  • Prof. Joan Bausells
    Centro Nacional de Microelectrónica (CNM-CSIC), Barcelona
  • Prof. Albert van den Berg
    University of Twente, The Netherlands
  • Prof. Andre Bernard
    Institut für Mikro- und Nanotechnologie (MNT-NTB), Buchs, Switzerland
  • Prof. H. Börner
    Max Planck Institute of Colloids and Interfaces, Golm, Germany
  • Prof. Josep Maria Canals
    University of Barcelona, Spain
  • Dr. Matthew Dalby
    University of Glasgow, Glasgow, UK
  • Prof. Paolo Dario
    Scuola Superiore Sant’Anna (SSSA), Pontedera, Italy
  • Prof. Ramón Eritja
    Institut de Recerca Biomédica (IRB), Barcelona, Spain
  • Prof. E. Faszewski
    Wheelock College, Boston, USA
  • Prof. G. Fuhr
    FhG Biomedicine, St. Ingbert, Germany
  • Dr. Juan C. Izpisúa
    Centro de Medicina Regenerativa (CMRB), Barcelona, Spain
  • Dr. Nicole Jaffrezic
    Université Claude Bernard Lyon 1, France
  • Dr. Graham Johnson
    Uniscan Instruments Ltd, Buxton, UK
  • Dr. Mª Pilar Marco
    Institute of Chemical and Environmental Research, Barcelona
  • Prof. Jean-Louis Marty
    Université de Perpignan Via Domitia, France
  • Prof. Barbara Mazzolai
    IIT Center for Micro-BioRobotics (CMBR), Pontedera, Italy
  • Dr. Edith Pajot
    Biology of Olfaction and Biosensors group (BOB) at INRA, Jouyen-Josas, France
  • Dr. M. Lluïssa Pérez
    Dept. Farmacología, University of Barcelona, Spain
  • Dr. Hernando del Portillo
    Centro de Investigación en Salud Internacional de Barcelona (CRESIB), Barcelona, Spain
  • Dr. Jaume Reventós
    Hospital Vall d’Hebrón, Barcelona, Spain
  • Prof. L. Reggiani
    Nanotechnology Laboratory, INFM, Lecce, Italy
  • Prof. Daniel Riveline
    Laboratory of Cell Physics ISIS/IGBMC, Strasbourg
  • Prof. M. Sampietro
    Politecnico di Milano, Italy
  • Prof. Molly M. Stevens
    Imperial College, London, UK
  • Dr. Christophe Vieu
    Laboratoire d’analyse et d’architectures des systèmes (LAASCNRS), Toulouse, France
  • Biokit S.A. (Werfen group)
  • Genomica S.A.U. (Zeltia group)
  • Tallers Fiestas S.L.
  • Enantia S.L.
  • Microfluidic ChipShop GmbH

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