A new molecular dimension: exploiting Raman spectroscopy in Biomedicine
Mónica Marro, ICFO, The Institute of Photonic Sciences
Raman spectroscopy is a promising optical technique that enables the investigation of the molecular content of biological samples in a rapid, non-invasive, label-free and multiplexed approach. In the biomedical field, it is of special interest because the device can be portable and cost-effective.
In this seminar, I will show my work exploiting Raman spectroscopy in a broad range of biomedical applications from the molecular, to cellular and tissue level. I will present how Raman spectroscopy can represent a step forward into different fields, namely: cancer diagnosis, patient stratification, and personalized medicine; neurodegeneration; and mechanobiology. I will show also optical developments that can improve Raman spectroscopy in the speed of image acquisition, like the Raman light sheet approach, or Surface Enhanced Raman spectroscopy.
Overall, I will show how Raman spectroscopy coupled with data science and developments in photonics and nano-engineering could revolutionize the biomedical field in the next years, providing new and other-wise inaccessible molecular information, and giving an unprecedented step towards a more rapid, accurate, personalized diagnosis and treatments.