PhD Discussions Session

An iCRISPR Platform for Human Functional Genetics in Human Pluripotent Stem Cells (hPSCs) Andrés Marco, Pluripotency for organ regenerationSelf-renewal and pluripotency are the two major functional properties defining human pluripotent stem cells (hPSCs), allowing them to be cultured indefinitely in a dish and maintaining their capacity to differentiate to virtually any human cell lineage, tissue ... Read more

An iCRISPR Platform for Human Functional Genetics in Human Pluripotent Stem Cells (hPSCs) Andrés Marco, Pluripotency for organ regenerationSelf-renewal and pluripotency are the two major functional properties defining human pluripotent stem cells (hPSCs), allowing them to be cultured indefinitely in a dish and maintaining their capacity to differentiate to virtually any human cell lineage, tissue ... Read more

Linking epithelial size, tension and pressure in curved epithelial monolayers Ariadna Marin, Integrative Cell and Tissue DynamicsEpithelia are thin cellular layers that act as mechanical and biochemical barriers. They are dynamic tissues that present strong intercellular junctions needed to maintain their integrity while growing and regenerating. During embryogenesis, they fold progressively and give rise to ... Read more

Linking epithelial size, tension and pressure in curved epithelial monolayers Ariadna Marin, Integrative Cell and Tissue DynamicsEpithelia are thin cellular layers that act as mechanical and biochemical barriers. They are dynamic tissues that present strong intercellular junctions needed to maintain their integrity while growing and regenerating. During embryogenesis, they fold progressively and give rise to ... Read more

Cellulose-based cryogels for long-term culture of pancreatic islets and skeletal muscle tissue Ferran Velasco, Biosensors for BioengineeringIslet encapsulation inside traditional hydrogels is one of the most common techniques to study insulin secretion for Diabetes Mellitus studies. However, it’s proved that cells encapsulated in a depth of more than 100 microns die due the lack of ... Read more

Cellulose-based cryogels for long-term culture of pancreatic islets and skeletal muscle tissue Ferran Velasco, Biosensors for BioengineeringIslet encapsulation inside traditional hydrogels is one of the most common techniques to study insulin secretion for Diabetes Mellitus studies. However, it’s proved that cells encapsulated in a depth of more than 100 microns die due the lack of ... Read more

Super-resolution microscopy for understanding the formation and inhibition of influenza virus structures Maria Arista, Nanoscopy for NanomedicineSuper-resolution microscopy is a mighty tool that has the ability to study fluorescence samples beyond the diffraction limit, achieving a spatial resolution around 20 nm. The study of viruses can greatly benefit from super-resolution imaging, mainly due to their ... Read more

Super-resolution microscopy for understanding the formation and inhibition of influenza virus structures Maria Arista, Nanoscopy for NanomedicineSuper-resolution microscopy is a mighty tool that has the ability to study fluorescence samples beyond the diffraction limit, achieving a spatial resolution around 20 nm. The study of viruses can greatly benefit from super-resolution imaging, mainly due to their ... Read more

Biochemical responses to cell membrane mechanical remodelling Xarxa Quiroga, Cellular and molecular mechanobiologyIn a range of physiological processes, from extravasation to endocytosis, cells are constantly submitted to morphological changes, which eventually entail plasma membrane reshaping and adaptation. This remodelling could be harnessed by cells to detect and respond to shape changes, enabling mechanosensing mechanisms. However, ... Read more

Biochemical responses to cell membrane mechanical remodelling Xarxa Quiroga, Cellular and molecular mechanobiologyIn a range of physiological processes, from extravasation to endocytosis, cells are constantly submitted to morphological changes, which eventually entail plasma membrane reshaping and adaptation. This remodelling could be harnessed by cells to detect and respond to shape changes, enabling mechanosensing mechanisms. However, ... Read more