Neurostimulation to correct neural circuit and motoneuron dysfunction Dr. Genís Prat Ortega, PhD in Computational Neuroscience at the Autonomous University of Barcelona. Neurostimulation therapies such as spinal cord stimulation (SCS) or deep brain stimulation have shown unprecedented clinical success in improving voluntary motor control. In this case the stimulation can be understood as a neuroprosthetic ... Read more
The Next-Generation Nanomedicine Network (NET-NANO) is hosting its third workshop on September 19th, focusing on emerging nanotherapeutic modalities. This event will explore the latest advancements in self-adaptive, stimuli-responsive, and immunomodulatory strategies for nanomedicine. The workshop will feature talks from both internal IBEC researchers and leading external experts, including plenary sessions by Prof. Hélder A. Santos, ... Read more
NET-RARE third workshop third workshop focuses on the latest technologies for identifying new biomarkers to enable early detection and better characterization of rare diseases. It also aims to explore strategies for using biomarkers to monitor disease progression and incorporate them as secondary endpoints in clinical trials. The session will open with Marina Giannotti from IBEC’s Nanoprobes & Nanoswitches group, whose research explores ... Read more
CHARACTERIZATION OF ENZYMATIC BIOELECTRODES BY IN SITU FLUORESCENCE MICROSCOPY A. de Poulpiquet,1 A. Guessab, 1 H. M. Man,1 I. Mazurenko,1 L. Bouffier,2 E. Lojou1 1Aix-Marseille Univ., CNRS, Bioenergetics and Protein Engineering, UMR 7281, Marseille 2 Institute of Molecular Sciences, UMR CNRS 5255, Univ. Bordeaux, ENSMAC, Pessac adepoulpiquet@imm.cnrs.fr Redox enzymes present remarkable catalytic properties (exceptional selectivity, ... Read more
“MICROFLUIDIC AND ROBOTIC PLATFORMS FOR TME-FRIENDLY CANCER DRUG EVALUATIONS” Albert Folch, Professor University of Washington, Bioengineering Dept. There is a lack of confidence in present in vitro disease models and drug efficacy tests, as they do not properly recapitulate the dynamic physiology and pathophysiology of the human organism. This challenge is particularly acute in oncology: ... Read more
Modelling optogenetic control of cell contractility Ulrich Schwarz, Heidelberg University Animal cells are highly dynamic and continuously generate force, for example for mechanosensing, cell division, cell migration, morphogenesis and regeneration. Their main force generators are non-muscle myosin II molecular motors that slide actin filaments past one another. We first discuss how myosin II minifilaments dynamically ... Read more
Involucrar als pacients, no és una moda passatjera Begonya Nafria Escalera, Patient Engagement in Research Head of Department at Sant Joan de Déu Chidren’s Hospital (Spain) La recerca i la innovació que respongui a les necessitats dels pacients, requereix involucrar-los en les fases inicials i durant la vida d’un projecte. En aquesta sessió parlarem sobre ... Read more
Mechanochemical feedback in model epithelial tissues Silke Henkes, Leiden Institute of Physics, Leiden University In the development of animals, tissues self-organise starting from a single cell into layers, shapes and patterns. This active mechanical process operates beyond the theoretical framework of reaction-diffusion equations such as Turing patterns. At the same time, combining active driving with ... Read more
Next-generation organoid models for colorectal cancer research Francisco Lorenzo-Martín, University of Salamanca Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of tumor structures. This has enabled better modelling of low-complexity cancer cell behaviors that occur over short periods of time. However, the currently available organoid systems lack ... Read more
A search for the right scientific question: can we fabricate cells and tissues from scratch? Prof. Pierangelo Gobbo, University of Trieste Bottom-up synthetic biology is an emerging research field whose objectives is to design and fabricate existing biological systems from inanimate molecules, materials, and chemical reactions. One of the key biological systems that bottom-up synthetic ... Read more