Neuronal infra-slow rhythm in the thalamic nucleus reuniens orchestrate hippocampo-prefrontal information flow during sleep Dr Pascale Quilichini, Institut de Neurosciences des Systèmes, INSERM, Aix-Marseille University The consolidation of episodic memory during sleep relies on coordinated interactions between the hippocampus (HPC) and the prefrontal cortex (PFC), although these regions lack direct reciprocal connections. The thalamic nucleus ... Read more
El proper 13 de maig a les 15:30 h s’inaugurarà al PCB (C/ Baldiri Reixac, 4-12 i 15 – 08028 Barcelona) l’exposició Diàlegs Oberts: Processos Compartits entre Art i Ciència. La mostra presenta les obres creades col·lectivament entre artistes i investigadorxs de l’IBEC, mostrant el procés creatiu compartit i les preguntes i intuïcions que han sorgit al llarg de la ... Read more
Studying the mechanical regulation of nucleocytoplasmic transport using Single Molecule Tracking Aina Albajar-Sigalé, Cellular and Molecular Mechanobiology Group Cellular function relies on the precise regulation of macromolecular transport between the cytoplasm and the nucleus, a process governed by Nuclear Pore Complexes (NPCs). While traditional understanding held that transport through NPCs was mainly dictated by the ... Read more
Steering Self-organization in Active Colloids and Droplets through Confinement Confinement, whether externally imposed or generated by the system itself, plays a central role in shaping the dynamics and self-organization of active matter. In natural systems, such as microbial communities and social insects, self-reinforced confinement is exploited to create functional structures and accomplish complex collective tasks. In contrast, the potential of such mechanisms ... Read more
Nuclear Envelope Remodelling under Mechanical Perturbation Margherita Gallano, predoctoral researcher in the Cellular and Molecular Mechanobiology Group Cells experience mechanical loads during many fundamental processes, including growth, differentiation, and migration. These forces are transmitted to the nucleus and can influence gene expression, ultimately modulating cell behaviour and determining cell fate. The Nuclear Envelope (NE) plays ... Read more
Epigenomic Control of Pancreatic β-Cell Development and Fate: Toward Engineering a Vascularized Organoid-on-Chip Platform Santiago A. Rodríguez-Seguí1,2 1 Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina. 2 Departamento de Fisiología, Biología Molecular y Celular, Universidad de Buenos Aires, Facultad de Ciencias Exactas ... Read more
The p53 pathway and metabolism: implications in normal tissue homeostasis, aging and cancer progression Dr. Le Cam , Montpellier Cancer Research Institute (IRCM) Mutation of the TP53 gene is the most frequent genetic alteration in human cancers. Tumor suppressive functions of p53 have been linked to its ability to control cell division, cell death and ... Read more
IBEC Day brings together the entire IBEC community for a day of exchange and connection, designed to share, connect and celebrate together. This year’s edition is particularly meaningful, as it forms part of the celebration of IBEC’s 20th anniversary, marking an important milestone for the institute and offering an opportunity to look back, recognise the ... Read more
On the occasion of the 20th anniversary of IBEC, we are pleased to invite the entire Alumni community to a special event taking place on June 18th at 5:30 pm at the Auditori Antoni Caparrós (PCB). This gathering aims to reconnect all those who have been part of IBEC over the past 20 years, share professional journeys, exchange experiences and strengthen a ... Read more
Bioactives Beyond Screening: From Molecular Potential to Local Gut Function Bioactive molecules are often selected through simplified screening assays, where antioxidant, antimicrobial, anti-inflammatory or cytotoxic responses provide an initial indication of biological potential. However, in the gastrointestinal context, this potential can be profoundly reshaped by digestion, solubility, mucus, microbiota metabolism, epithelial interactions and the local ... Read more