Esdeveniments

Polymer-Nanoparticle Hydrogels Enabling Innovations in Cell and Drug Deliver Eric A. Appel, Associate Professor of Materials Science & Engineering at Stanford University Dynamic biomaterials exhibit highly useful properties that are impossible with traditional materials but crucial for a wide variety of emerging applications in biomedicine. These materials typically employ enthalpy-dominated crosslinking interactions that become weaker ... Read more

Decision-making during cell migration Pablo J. Sáez, PhD Cell Communication and Migration Laboratory, UKE, Hamburg Moving cells navigate inside living tissues often encountering obstacles and junctions, where their path branches into alternative directions of migration. This is the case of cells moving on top or within blood vessels, which often bifurcate into branches. Cells have diverse migratory ... Read more

Bioinspired soft-matter systems: engineering life-like behaviors Assoc. Prof. Laura Alvarez, Associate Professor at the University of Bordeaux and leads the Soft BioColloids group at the Centre de Recherche Paul Pascal (CRPP, CNRS) Cells, even in their simplest forms, exhibit adaptive motion and task execution, capabilities underpinned by their complex and hierarchized architecture, and their ability ... Read more

Neuronal infra-slow rhythm in the thalamic nucleus reuniens orchestrate hippocampo-prefrontal information flow during sleep Dr Pascale Quilichini, Institut de Neurosciences des Systèmes, INSERM, Aix-Marseille University The consolidation of episodic memory during sleep relies on coordinated interactions between the hippocampus (HPC) and the prefrontal cortex (PFC), although these regions lack direct reciprocal connections. The thalamic nucleus ... Read more

Studying the mechanical regulation of nucleocytoplasmic transport using Single Molecule Tracking Aina Albajar-Sigalé, Cellular and Molecular Mechanobiology Group Cellular function relies on the precise regulation of macromolecular transport between the cytoplasm and the nucleus, a process governed by Nuclear Pore Complexes (NPCs). While traditional understanding held that transport through NPCs was mainly dictated by the ... Read more

Steering Self-organization in Active Colloids and Droplets through Confinement Confinement, whether externally imposed or generated by the system itself, plays a central role in shaping the dynamics and self-organization of active matter. In natural systems, such as microbial communities and social insects, self-reinforced confinement is exploited to create functional structures and accomplish complex collective tasks. In contrast, the potential of such mechanisms ... Read more

Nuclear Envelope Remodelling under Mechanical Perturbation Margherita Gallano, predoctoral researcher in the Cellular and Molecular Mechanobiology Group Cells experience mechanical loads during many fundamental processes, including growth, differentiation, and migration. These forces are transmitted to the nucleus and can influence gene expression, ultimately modulating cell behaviour and determining cell fate. The Nuclear Envelope (NE) plays ... Read more

Epigenomic Control of Pancreatic β-Cell Development and Fate: Toward Engineering a Vascularized Organoid-on-Chip Platform Santiago A. Rodríguez-Seguí1,2 1 Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina. 2 Departamento de Fisiología, Biología Molecular y Celular, Universidad de Buenos Aires, Facultad de Ciencias Exactas ... Read more

The p53 pathway and metabolism: implications in normal tissue homeostasis, aging and cancer progression Dr. Le Cam , Montpellier Cancer Research Institute (IRCM) Mutation of the TP53 gene is the most frequent genetic alteration in human cancers. Tumor suppressive functions of p53 have been linked to its ability to control cell division, cell death and ... Read more