Development of chemical and synthetic biology tools to generate biotherapeutics and to tackle brain diseases
Dr. Benjami Oller-Salvia, IQS
In our group we develop chemical and synthetic biology tools to generate biotherapeutics and to tackle brain diseases. In the first part of the talk, I will report our efforts toward developing strategies to construct conditionally-active biotherapeutics that target antigens considered undruggable. In the second part of the talk, I will present our work on peptides for drug delivery across the blood brain barrier. There, I will highlight the recent development of a new family of bicyclic brain shuttles and provide a hint toward new ways of exploring brain transport. .