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New study reveals how protein behaviour drives blood–brain barrier specialization

The research, led by the Institute for Bioengineering of Catalonia, reveals that the blood–brain barrier is defined not only by the proteins it expresses, but by how it uses them, through a dynamic property known as endocytic turnover rate (ETOR). This discovery shows that brain endothelial cells have a unique molecular behaviour that distinguishes them from other blood vessels and can be disrupted during inflammation. The results provide new insight into how the barrier functions and fails in disease which may help identify novel therapeutic strategies to restore neurovascular health.

Thematic Network. NET-QUASI Workshop 4

Constructing Biological Complexity: Engineering Interactions Across Scales  Biological systems achieve remarkable functionality through interactions that span multiple scales, from molecular assemblies and cellular compartments to tissues and complex microenvironments. Understanding … Read more

IBEC participates in three projects that have contributed to COVID-19 advances driven by La Marató 2020

On 18 June, the results were announced for the 36 research projects funded by La Marató de 3Cat through its 2020 special call for proposals dedicated to tackling the novel coronavirus (SARS-CoV-2). The Institute for Bioengineering of Catalonia (IBEC) participated in three of these projects, which aimed to deepen our understanding of the disease and improve its diagnosis and clinical monitoring.