Engineering enzymes for biomedical and biotechnological applications Emilio Parisini, Latvian Institute of Organic Synthesis (Riga, Latvia), University of Bologna (Italy) Enzyme engineering has the potential to improve the activity, the stability and the substrate recognition of enzymes. As such, it paves the way for the design of novel enzymes with improved performances for a wide ... Read more
Delivering effector molecules in cells in vitro and ex vivo by photoporation. Kevin Braeckmans, Biophotonics Research Group, Lab. General Biochemistry and Physical Pharmacy, Ghent University, Belgium Delivery of bioactive compounds, such as proteins and nucleic acids, into cells in vitro or ex vivo is a generic requirement for many applications in the life sciences, such ... Read more
Cell migration and morphogenesis in viscoelastic matrices Ovijit Chaudhuri, University of Standford The extracellular matrix (ECM) is a complex assembly of structural proteins that provides physical support and biochemical signaling to cells in tissues. Over the last two decades, studies have revealed the important role that ECM elasticity plays in regulating a variety of biological ... Read more
Biomicrofluidic analysis of hematological diseases by means of mathematical biomechanical models and statistical analysis: Cells and hydrogels in microchannels and microrheometers Aurora Hernandez-Machado, Departament de Fisica de la Materia Condensada, Universitat de Barcelona We have developed microfluidic devices for precise characterization of hematological diseases. By means of one drop of blood and mathematical models based ... Read more
2P-BRAINSCOPY: pushing the boundaries of two-photon microscopy to study large neuronal networks in behaving mice. Nicolò Accanto, Inserm researcher at the in Insitut de la Vision (IDV), in the group of Valentina Emiliani, Paris In the past 15 years, the synergy of two-photon (2P) microscopy and optogenetics has transformed neuroscience, enabling high-resolution imaging and precise photostimulation ... Read more
We are glad to invite you to this seminar organized by IBEC where Marek W. Radomski, Vice-Dean Research College of Medicine, University of Saskatchewan, Saskatoon, Canada will talk about the Canadian health research following COVID-19 pandemic, the next Tuesday 14th of May at 15h at the Faculty of Medicine Clinic (UB). Marek W. Radomski, Vice-Dean of Investigation College ... Read more
Beating Organs-on-Chip: leveraging on motion to mimic human organ physiological/diseased states in vitro Erika Ferrari, Commercial Science Leader, BiomimX Srl Beating Organs-on-Chip are in vitro miniaturized models developed within the uBeat® platform, which integrates microfluidics, 3D human cell culture and controlled mechanical stimulation to recapitulate, with unprecedented precision and predictability, clinically relevant models reflective of ... Read more
Single molecule insights into cellular mechanotransduction Sergi Garcia-Manyes, Single Molecule Mechanobiology laboratory, The Francis Crick Institute and King’s College London Cellular mechanostransduction relies on the conversion of mechanical cues into chemical signals, which propagate from the focal adhesion hub through the cytoskeleton to ultimately reach the nucleus through the Nuclear Pore Complex (NPC), and ... Read more
Engineering the Nanoscale Membrane Topography in Cells Wenting Zhao, School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore and Institute for Digital Molecular Analytics and Science (IDMxS), Singapore Abstract. Cell membranes serve as a central platform to host a variety of proteins essential for cellular activities such as cell signaling, morphogenesis, and membrane ... Read more
Enhanced regeneration through in vivo cell reprogramming: lessons from the first decade of research and a success story in the mouse heart Irene de Lázaro, PhD1,2,3 1 Department of Biomedical Engineering, NYU Tandon School of Engineering, New York University 2 Cardiovascular Research Center, NYU School of Medicine and NYU Langone Health 3 Harvard John A ... Read more