Registration is now open for the 14th IBEC Symposium on Bioengineering for Regenerative Therapies The 14th IBEC Symposium will focus on one of our three main areas of application of research at IBEC: Regenerative Therapies. Although this year the pandemic situation has improved, we still believe it is not safe enough to organize the symposium ... Read more
¡Adéntrate en la nano-escala: descubre y juega con el Microscopio de Fuerza Atómica! Desde que en la década de los 80 se inventara el microscopio de sonda de barrido, han sido muchos y muy relevantes los descubrimientos que estas técnicas han proporcionado al conocimiento científico. Aun hoy, es un instrumento capaz de detectar fenómenos increíbles que se dan en ... Read more
Vine a l’IBEC durant la Setmana de la Ciència i podràs conèixer els últims avenços sobre la recerca en Parkinson, visitar els nostres laboratoris i parlar amb els i les protagonistes d’aquesta recerca. En el marc de la setmana de la ciència, us convidem a una jornada de portes obertes on podreu visitar els laboratoris ... Read more
Targeted protein degradation: genetic determinants and drug discovery opportunities Cristina Mayor-Ruiz, IRBarcelona Targeted protein degradation is a new therapeutic modality based on drugs that destabilize proteins by inducing their proximity to E3 ubiquitin ligases. Of particular interest are "molecular glue degraders": compounds that can degrade otherwise unligandable proteins by orchestrating direct interactions between target and E3. However, ... Read more
Assessment of trunk function in patients with spinal cord injury using electromyography and smartphone accelerometry Yolanda Castillo, Biomedical Signal Processing and Interpretation Spinal cord injury (SCI) causes motor and sensory impairment below the level of the injury, but also many other health problems. A common consequence of SCI is the lack of control over trunk ... Read more
The effect of gene loss on adaptation | 3D cell shape analysis in embryos Rob Jelier, CMPG - Predictive Genetics and Multicellular Systems University of Leuven In this talk I will summarize two research projects. First, I will report on a large-scale experimental evolution study into the effect of gene deletion on adaptation. We found ... Read more
Therapeutic effects of HDAC3 inhibition on spinal injuries and autoimmune demyelinating diseases Arnau Hervera, Molecular and Cellular Neurobiotechnology The molecular mechanisms discriminating between regenerative failure and success remain elusive. While a regeneration-competent peripheral nerve injury mounts a regenerative gene expression response in bipolar dorsal root ganglia (DRG) sensory neurons, a regeneration-incompetent central spinal cord injury ... Read more
Updates on a new lab at IBEC: hyperpolarised magnetic resonance for real-time, in situ monitoring of cell metabolism Irene Marco, Molecular Imaging for Precision Medicine group at IBEC There is a clinical need for non-invasive and reliable markers to diagnose, stage and evaluate treatment response in many diseases such as cancer or non-alcoholic fatty liver ... Read more
Investigating Pathological Extracellular Matrix Architecture The composition and architecture of the extracellular matrix (ECM), and their dynamic alterations, play an important regulatory role on numerous cellular processes. Furthermore, structural and biochemical properties of the ECM are central in regulating cell behavior via mechanical, chemical and topological cues detected by receptors in the cell membrane which ... Read more
Factores físicos y moleculares implicados en la migración celular y en el desarrollo de la corteza cerebral. Ana López Mengual, Molecular and cellular neurobiotechnology group Abstract Cell migration acquires special relevance during embryonic development and tissue regeneration. During the development of the adult individual, cells multiply, differentiate and mature, having to move to their destination ... Read more