Towards an evolutionary-driven universal therapy against (intracellular) pathogens Università degli Studi di Milano We are living a time where we believe antibiotics are the cornerstone of any infectious disease-based therapy. It is definitely out of question that antibiotics saved millions of people worldwide in the last century, and that they are still doing it very ... Read more
Building tissues to understand how tissues build themselves Zev Gartner, UCSF Cells assemble into tissues and organs through an active process termed self-organization. Harnessing tissue self-organization will ultimately advance applications as diverse as disease modeling and regenerative medicine, while revealing new strategies for fighting disease. However, progress towards these applications is limited by our incomplete ... Read more
Organ on a chip models to emulate multi systemic metabolic diseases Javier Ramon, IBEC Existing on-chip tissue models typically represent a single organ, limiting systemic drug investigations. Microscale tissue analog systems aim to improve drug and toxicity predictions across various organs. However, multi-organ devices are limited, and none have explored skeletal muscle and pancreatic islets. ... Read more
Single molecule electrochemical studies of photosynthetic complexes Author: Manuel López Ortiz, Nanoprobes and Nanoswitches group Reading date: 14/07/2023 Reading time: 10:00 Reading place: Aula de graus Dufort de la facultat de biologia
Mechanics of crypt folding, tissue compartmentalization and collective cell migration in intestinal organoids Author: Gerardo Ceada, Integrative cell and Tissue Dynamics group Reading date: 14/07/2023 Reading time: 12:00 Reading place: Aula Magna de la Facultad de Medicina de la Universidad de Barcelona (Campus Clínic)
Translation and Initial Patient and Volunteer Studies with Hyperpolarized Carbon-13 MR Molecular Imaging Dan Vigneron, Department of Radiology & Biomedical Imaging, University of California San Francisco "Hyperpolarized (HP) carbon-13 MRI is an emerging molecular imaging method to monitor enzymatic conversions through key, previously-inaccessible biochemical pathways. Over 1000 human HP carbon-13 MR studies to date have ... Read more
Mechanical phenotyping of cancer stemness in colorectal cancer. Author: Sefora Conti, Integrative cell and Tissue Dynamics group Reading date: 18/07/2023 Reading time: 15:00 Abstract: Colorectal cancer tumors are composed of heterogeneous and plastic cell populations, including a pool of cancer stem cells that express LGR5. Whether these distinct cell populations display different mechanical properties, and how ... Read more
Awake brain surgery mapping - a way to mitigate postsurgical impairments and a door to understanding human cognition MDr Joanna Sierpowska from the Department of Cognition, Development and Educational Psychology, Institute of Neurosciences, University of Barcelona Brain mapping for language and cognition during awake brain surgeries helps neurosurgeons to mitigate postsurgical impairments. At the same ... Read more
Highlights of 20 years DNP with Merck as partner Matthias Schulze, Merck Introduction of Merck’s capabilities to supply specifically labeled tracers in different grades. Describing the milestones of DNP towards establishing that method as a powerful tool in cancer diagnostics. Outlining the challenges and the scope on projects utilizing 13 C labeled reagents. Matthias Schulze ... Read more
Reprogramming the Factory of Life to Target the Delivery of mRNA via Helical Chirality Virgil Percec, Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia Homochiral helical self-organizations are known at the macroscopic level in nature, art, architecture and science for thousands of years . However, molecular helicity was discovered in proteins ... Read more