Urea-powered nanomotors a promising therapy for bladder cancer
IBEC’s Smart Nano-Bio-Devices group have published a paper describing nanomotors that can attack 3D bladder cancer spheroids in vitro.
The nanomotors carry anti-FGFR3 on their outer surface, an antibody that not only enables cancerous cells to be specifically targeted, but also inhibits the fibroblast growth factor signaling pathway, suppressing tumor growth. Crucially, the fuel that gives the nanomotors the capability of autonomous motion is urea, which is present at high concentrations in the bladder – making these particular nanomotors a promising avenue for this particular cancer.
Pere Roca-Cusachs, group leader at IBEC and assistant professor at the University of Barcelona, has won the 2019 Young Investigator Prize for his contributions to the field of mechanobiology. The award is given by the European Biophysical Societies Association (EBSA).
The MECHANO·CONTROL consortium, led by several research institutions across Europe, is launching a Summer School that will be taking place between 17-20 of September 2019 at the Eco Resort in La Cerdanya. The aim of the summer school is to provide training on mechanobiology, and specifically its application to breast cancer.