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Decoding the Mechanics of Brain Endothelium: CAV1-Dependent Invaginations as modulators of neurovascular coupling Fidel Lolo Romero Endothelial cells of the brain vasculature are continuously exposed to mechanical forces that regulate essential functions including endocytosis, barrier integrity, and neurovascular coupling (NVC). Plasma membrane (PM) tension serves as a critical mechanotransductive cue, and specialized PM invaginations—such as ... Read more