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Next-generation organoid models for colorectal cancer research Francisco Lorenzo-Martín, University of Salamanca Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of tumor structures. This has enabled better modelling of low-complexity cancer cell behaviors that occur over short periods of time. However, the currently available organoid systems lack ... Read more |
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Decoding the Mechanics of Brain Endothelium: CAV1-Dependent Invaginations as modulators of neurovascular coupling Fidel Lolo Romero Endothelial cells of the brain vasculature are continuously exposed to mechanical forces that regulate essential functions including endocytosis, barrier integrity, and neurovascular coupling (NVC). Plasma membrane (PM) tension serves as a critical mechanotransductive cue, and specialized PM invaginations—such as ... Read more |
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