IBEC has a wide expertise in designing, fabricating and characterizing biomaterials for use in biological and health applications, in particular regenerative therapies. We put emphasis both in the study of the physicochemical properties of materials and in understanding and tuning the cell-material interactions, biocompatibility, proteins or cell adhesion, proliferation, etc, to obtain rational and functional biomaterials.
EXPERTISE DETAILS
- Fabrication
- 3D Bioprinting to develop advanced biomimetic materials for cell-therapy and tissue engineering to treat chronic spinal cord injury, diabetes, and liver diseases.
- Development of microenvironments for tissue regeneration: cell-derived matrices for 3D in vitro cancer cell models, Decellularized tissues for development of 3D models, Multimodal platforms for tissue regeneration, Development of biomaterials that stimulate tissue regeneration (Cardiac, oral mucosa, skin, bone).
- 3D printing and photopolymerization (visible light and UV), patterning, molding and replica molding, microcontact printing and hot-embossing.
- Characterization
- Topographical characterization of hard and soft surfaces (membranes/polymers), and characterization of nanomechanical properties.
- Electrochemical methods, including voltammetry and impedance spectroscopy for the characterization of materials, membranes and proteins.
- Study of cell and cell-material behavior
- Study of cell behavior as a function of the substrate stiffness or under mechanical stress. Control of biological processes though substrate properties tuning.
- Determination of membrane mechanics and fluidity, and evaluation of membrane proteins behavior under mechanical stress.
- Surface nano-structuration and functionalization for cellular functional response, like adherence, differentiation, etc.