Protein interactions gone awry in neurodegenerative disease Danny Hatters, Department of Biochemistry and Pharmacology | Faculty of Medicine, Dentistry and Health Sciences The University of Melbourne,  Australia The Hatters lab studies impacts of protein misfolding and aggregation in cultured cell models of neurodegenerative diseases. We have developed approaches to examine principles governing how proteins inappropriately ... Read more

How does ageing-related stiffening of brain tissue microenvironments affect the regenerative capacity of cns progenitor cells Professor of biology and bioengineering, the Hebrew University of Jerusalem, Israel. Ageing-related stiffening of neuronal microenvironments in the brain generates potent signals that attenuate the regenerative capacity of oligodendrocyte progenitor cells (OPCs) to proliferate and differentiate. We find that ... Read more

Mechanical impact of cell delamination on tissue dynamics, in developmental and tumoral contexts Centre de Biologie Intégrative, CNRS/UMR 5088, Université Toulouse III, Toulouse, France How mechanical forces drive morphogenesis is a fundamental question in the field of biomechanics. Combining imaging, genetics, biophysical and modeling approaches, we found that apoptotic cells, far from being eliminated passively, ... Read more

Development of chemical and synthetic biology tools to generate biotherapeutics and to tackle brain diseases Dr. Benjami Oller-Salvia, IQS In our group we develop chemical and synthetic biology tools to generate biotherapeutics and to tackle brain diseases. In the first part of the talk, I will report our efforts toward developing strategies to construct conditionally-active ... Read more