Alzheimer Archives - Institute for Bioengineering of Catalonia

March 30, 2023March 29, 2023

A blood-brain barrier on a chip to study drugs against Alzheimer’s

A study led by the Institute of Bioengineering of Catalonia (IBEC) describes the development of an organ-on-a-chip that mimics the human blood-brain barrier. With this system, researchers can study the … Read more

December 15, 2022December 14, 2022

A new atlas unveils which mutations are behind the noxious amyloid formation

Researchers from the Institute for Bioengineering of Catalonia (IBEC) have developed the most complete atlas up to date of the genetic mutations that cause the formation of amyloid beta fibril, … Read more

July 22, 2021July 21, 2021

Benedetta Bolognesi and Ben Lehner win competitive funding to join forces against neurodegenerative diseases

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The “la Caixa” Foundation will fund a large and innovative research project co-led by IBEC Junior Group Leader Benedetta Bolognesi and by ICREA research professor Ben Lehner at CRG, which aims to gain a better understanding of the genetic causes leading to neurodegenerative diseases. Researchers will combine deep mutagenesis and machine learning techniques to produce a “map of dementia” as a method to predict whether a person is more susceptible to suffer these diseases.

March 22, 2021March 15, 2021

One more step towards early detection of Alzheimer’s

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Benedetta Bolognesi, junior group leader at IBEC, appears in different media for a recent study published in the eLife magazine. In the study they show the first map with all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer’s disease.

March 9, 2021March 9, 2021

First comprehensive map of amyloid plaque mutations opens new avenues for early detection of Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer’s disease.