IBEC Seminar

Toward the next generation of 3D optical microscopes: faster, deeper, and label-free Martí Duocastella, Departament de Fisica Aplicada, Universitat de Barcelona Three-dimensional (3D) optical microscopy is the tool of choice for characterizing the structure and dynamics of biological systems at sub-cellular resolution. However, most microscope architectures are tailored to capture two-dimensional (2D) information from moderately ... Read more

Epithelial Cell Variability is Governed by Physics Principles and Has Mechanobiology Impacts Dr. Neil Lin,  Assistant Professor of Mechanical Engineering and Bioengineering at University of California, Los Angeles (UCLA). Biological systems inherently exhibit variability, seen in diverse cell shapes, sizes, and mechanical properties. Despite its prevalence, our understanding of the role of phenotypic heterogeneity in ... Read more

Smart artificial microcompartments: motility and communication Pavan Kumar Bosukonda, Assistant Professor at the Department of Chemistry, Indian Institute of Technology Roorkee   Nature is a continuous source of inspiration for the design of smart and intelligent materials. In particular, cells which are the building blocks of life display a complex symphony of various chemical/physical processes ... Read more

Reverse engineering human heart  development with pluripotent stem cells Prof. Aitor Aguirre, Institute for Quantitative Health Science and Engineering (IQ) and the Department of Biomedical Engineering at Michigan State University  During development, an exquisitely orchestrated series of biological processes lay down the map for the entirety of our bodies and carry it out to perfection. ... Read more

Mechanisms of Organelle Remodeling for Cellular Function Al Jord, Group leader of Mechanisc of organelle remodeling group, Centre for Genomic Regulation, Barcelona To function, organisms rely on vital organs which, in turn, rely on specialized cells. At the subcellular scale, cell specialization is notably driven by robust mechanisms of organelle remodeling. Thus, discovering these mechanisms ... Read more

Blood biomarkers for Alzheimer’s disease: advancing diagnosis and patient care Marc Suárez-Calvet, Barcelonabeta Brain Research Center, Fundació Pasqual Maragall, Servei de Neurologia, Hospital del Mar.   In recent years, one of the most significant breakthroughs in Alzheimer's disease research has been the emergence of blood biomarkers that offer accurate detection of AD. Our research group ... Read more

Vaccinia in & as next-gen oncolytic virotherapy: exploiting the synergy between oncolysis and chemotherapy Dr Ernesto Mejías Pérez Ramón y Cajal researcher Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Universidad de Córdoba. Dpto. de Biología Celular, Fisiología e Inmunología In the fight against cancer, conventional treatments fall short of healthcare expectations. Oncolytic virotherapy is ... Read more

Molecular and mechanical regulation of abscission in stem cells Agathe Chaigne, PhD., Group leader. Cell Biology, Neurobiology and Biophysics department, Utrecht University, The Netherlands Abscission is the last step of cell division leading to the complete separation of the two sister cells and consists in the cutting of a cytoplasmic bridge. Abscission is mediated by ... Read more

Engineering enzymes for biomedical and biotechnological applications Emilio Parisini, Latvian Institute of Organic Synthesis (Riga, Latvia), University of Bologna (Italy) Enzyme engineering has the potential to improve the activity, the stability and the substrate recognition of enzymes. As such, it paves the way for the design of novel enzymes with improved performances for a wide ... Read more

Delivering effector molecules in cells in vitro and ex vivo by photoporation. Kevin Braeckmans, Biophotonics Research Group, Lab. General Biochemistry and Physical Pharmacy, Ghent University, Belgium Delivery of bioactive compounds, such as proteins and nucleic acids, into cells in vitro or ex vivo is a generic requirement for many applications in the life sciences, such ... Read more