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Elisabeth Engel at “El Método” podcast

Second release of our monthly collaboration with Luís Quevedo at “El Método” podcast. It’s Elisabeth Engel’s turn, principal investigator of the “Biomaterials for regenerative therapies” at IBEC talking about biomaterials, 3D bioprinting, personalised medicine among other things.

IBEC coordinates a project to promote skin regeneration using nanoparticles and 3D printing

Elisabeth Engel, principal investigator of the “Biomaterials for regenerative therapies” group at IBEC will coordinate a three-year project with the aim of boosting skin self-regeneration. This transnational European consortium composed of four more partners will develop the project over the next 3 years, including Dimitrios Zeugolis (University of Ioannina, Greece), Joan Pere Barret (Hospital Universitari Vall d’Hebron, Spain), Olivier Stephan (Université Grenoble-Alpes, France) and Denis Barbier (MicroLight 3D, France).

The project falls under the scope of EuroNanoMed3 programme, and the consortium will receive a total of 747.000 € through the corresponding national funding agencies of the countries involved. In particular, the “Agencia Estatal de Investigación” (Ministerio de Ciencia, Innovación y Universidades) will fund IBEC’s contribution with 190.000 €.

Elisabeth Engel en radio Euskadi

On the occasion of the annual meeting of the centres of excellence “Severo Ochoa and Maria de Maeztu” (SOMMa) at the 100xCiencia event, held in San Sebastián on November 22 and 23, Elisabeth Engel spoke on radio Euskadi about the intelligent devices they are developing in their laboratory. These bandages release nanoparticles containing calcium ions that are able to heal chronic lesions such as ulcers.

Biomaterials as signal-releasing platforms

IBEC’s Biomaterials for Regenerative Therapies group has published a review of the state-of-the-art in biomaterials for skin healing that proposes a move towards more personalized, in situ therapies.

Skin wound healing repairs and restore tissue through a complex process that involves different cells and signalling molecules that regulate cellular response and the remodelling of the extracellular matrix. Publishing in Advanced Drug Delivery Reviews, the article begins by summarizing recent advances in therapies for healing that combine biomolecule signals such as growth factors and cytokines with cells.

A material that encourages blood vessels to form

In a further step forward in their quest to achieve functional biomaterials for tissue regeneration, IBEC’s Biomaterials for Regenerative Therapies group has revealed a new construct that enhances blood vessel formation and maturation in vivo.

In the paper published in Acta Biomaterialia at the end of last year, the group and their collaborators at the Georgia Institute of Technology present a new implantable hydrogel that contains both human mesenchymal stromal cells (hMSCs) and calcium-releasing microparticles.