Supercomputer-based virtual humans: the future of medicine NOW Mariano Vázquez, ELEM Biotech & Barcelona Supercomputing Center In this talk we are going to address the potential of supercomputer-based virtual humans for the biomedical realm. Virtual Humans are computational "avatars" of a patient, which combines data with a mathematical model which are used to predict (as opposed ... Read more
New technologies for accelerating drug discovery and preclinical testing Maria Majellaro, Chief Scientific Officer of Celtarys. Abi J Vazquez. Co-founder and COO of DIVERSA Technologies SL. Bruno K Rodiño-Janeiro, Chief Scientific Officer of BFlow. Celtarys, DIVERSA and BFlow belong to the Galician biotechnology ecosystem and are dedicated to provide cutting-edge technologies applied in different ... Read more
Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes Simone Reber, Max Planck Institut for Infection Biology, Berlin (invited by Pere Roca-Cusachs) The packing and confinement of macromolecules in the cytoplasm and nucleoplasm has profound implications for cellular biochemistry. How intracellular density distributions vary and affect cellular physiology remains largely unknown. We show that the ... Read more
Microfluidic technology enabling biomedical applications Jaap den Toonder, Microsystems Research Section, Department of Mechanical Engineering, and Institute for Complex Molecular Systems, Eindhoven University of Technology. Currently, visiting professor at IBEC, Barcelona Microfluidics is the science and technology of manipulating and analyzing fluid flow at small scales, typically from millimeters down to micrometers. At these scales, ... Read more
What can microfluidic technologies offer during self-assembly processes? Josep Puigmartí-Luis, Departament de Ciència dels Materials i Química Física, Institut de Química Teòrica i Computacional (invited by César Rodriguez-Emmenegger) Self-assembly has long being used to control covalent and non-covalent interactions where molecular design has been the major driving force to achieve a desired outcome. Like in ... Read more
Toward the next generation of 3D optical microscopes: faster, deeper, and label-free Martí Duocastella, Departament de Fisica Aplicada, Universitat de Barcelona Three-dimensional (3D) optical microscopy is the tool of choice for characterizing the structure and dynamics of biological systems at sub-cellular resolution. However, most microscope architectures are tailored to capture two-dimensional (2D) information from moderately ... Read more
Epithelial Cell Variability is Governed by Physics Principles and Has Mechanobiology Impacts Dr. Neil Lin, Assistant Professor of Mechanical Engineering and Bioengineering at University of California, Los Angeles (UCLA). Biological systems inherently exhibit variability, seen in diverse cell shapes, sizes, and mechanical properties. Despite its prevalence, our understanding of the role of phenotypic heterogeneity in ... Read more
Smart artificial microcompartments: motility and communication Pavan Kumar Bosukonda, Assistant Professor at the Department of Chemistry, Indian Institute of Technology Roorkee Nature is a continuous source of inspiration for the design of smart and intelligent materials. In particular, cells which are the building blocks of life display a complex symphony of various chemical/physical processes ... Read more
Reverse engineering human heart development with pluripotent stem cells Prof. Aitor Aguirre, Institute for Quantitative Health Science and Engineering (IQ) and the Department of Biomedical Engineering at Michigan State University During development, an exquisitely orchestrated series of biological processes lay down the map for the entirety of our bodies and carry it out to perfection. ... Read more
Mechanisms of Organelle Remodeling for Cellular Function Al Jord, Group leader of Mechanisc of organelle remodeling group, Centre for Genomic Regulation, Barcelona To function, organisms rely on vital organs which, in turn, rely on specialized cells. At the subcellular scale, cell specialization is notably driven by robust mechanisms of organelle remodeling. Thus, discovering these mechanisms ... Read more