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Compartmentalised microfluidic culture systems for in vitro modelling of neurological and neuromuscular microenvironments Maider Badiola, Nanobioengineering group Movement of skeletal-muscle fibres is generated by the locomotion circuit. Failures in any part of the circuit can cause or define the severity of neuromuscular diseases (NMD), such as amyotrophic lateral sclerosis (ALS). Conventional in vitro study models ... Read more
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Breaking Paradigms: Delivering insulin orally Ester Caffarel, MIT Biologics have revolutionized disease treatment; however, their rapid degradation and poor absorption in the gastrointestinal (GI) tract generally limit their administration to parenteral routes. Devices for the oral delivery of biologics must aid in both localization and permeation to achieve systemic drug uptake. For this purpose, we ... Read more |
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Membraneless compartments based on intrinsically disordered proteins: from biology towards new protein materials Paolo Arosio, Institute for Chemical and Bioengineering, ETH Zurich In the last few years, discoveries in biology are revealing that a class of intrinsically disordered protein sequences plays an important role in the formation of cellular membraneless compartments by spontaneous liquid-liquid phase ... Read more |
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Diabetes, where are we? Anna Novials, PI of the group “Pathogenesis and Prevention of Diabetes” at IDIBAPS/Clinic Hospital of Barcelona and member of CIBERDEM network. Diabetes mellitus (DM) is a group of chronic metabolic disorders all characterized by hyperglycemia. It occurs either when the pancreas does not produce enough insulin or when the peripheral tissues ... Read more |
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Subjective ratings of emotive stimuli predict the impact of the COVID-19 quarantine on affective states Héctor López Carral, SPECS lab, IBEC The COVID-19 crisis resulted in a large proportion of the world’s population having to employ social distancing measures and self-quarantine. Given that limiting social interaction impacts mental health, we assessed the effects of quarantine on emotive perception ... Read more |
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