3D architecture and mechanism of touch detection in the Pacinian corpuscle Slav Bagriantsev, Associate Professor of Cellular & Molecular Physiology, Yale School of Medicine, USA Pacinian corpuscles are specialized mechanoreceptor end-organs that detect transient touch and high-frequency vibration in the skin and viscera of many vertebrates. Corpuscles have a complex cellular organization, which includes a ... Read more
Mechanical imprints of cell fate and cell competition Benoît Ladoux, Institut Jacques Monot (IJM) Paris Epithelia are communities of cells with close intercellular communications and of highly ordered coordination in their motion. Mechanical properties of epithelial tissues are important for our understanding of many vital biological processes, including homeostasis, morphogenesis, and metastasis and are tightly ... Read more
Translating fear mechanisms between humans and mice Raül Andero Galí, PhD, ICREA Research Professor at the Institute of Neurosciences of the Autonomous University of Barcelona Sex-specific mechanisms in fear memory and extinction may explain certain neuropsychiatric disorders like Post-Traumatic Stress Disorder (PTSD). In male mice, chemogenetic silencing of centromedial amygdala (CeM)-Tac2 fibers in the lateral ... Read more