IBEC Seminar

Drugging the undruggable: towards the development of selective modulators of cadherin-mediated cell-cell adhesion Emilio Parisi, Italian Institute of Technology (Milano) and Latvian Institute of Organic Synthesis (Riga) Cadherins are transmembrane calcium-dependent cell adhesion proteins that mediate cellular adherens junction formation and tissue morphogenesis. Loss of cadherin-mediated adhesion has been implicated in many different steps of ... Read more

Drugging the undruggable: towards the development of selective modulators of cadherin-mediated cell-cell adhesion Emilio Parisi, Italian Institute of Technology (Milano) and Latvian Institute of Organic Synthesis (Riga) Cadherins are transmembrane calcium-dependent cell adhesion proteins that mediate cellular adherens junction formation and tissue morphogenesis. Loss of cadherin-mediated adhesion has been implicated in many different steps of ... Read more

Cochlear optical stimulation of the auditory pathway Antoine Huet , Institut für Auditorische Neurowissenschaften, Universitätsmedizin Göttingen Optical stimulation of spiral ganglion neurons (SGNs) in the ear for coding sound information provides an interesting alternative to electrical stimulation that is used in current cochlear implants for hearing restoration. As light can be conveniently confined in space, ... Read more

Cochlear optical stimulation of the auditory pathway Antoine Huet , Institut für Auditorische Neurowissenschaften, Universitätsmedizin Göttingen Optical stimulation of spiral ganglion neurons (SGNs) in the ear for coding sound information provides an interesting alternative to electrical stimulation that is used in current cochlear implants for hearing restoration. As light can be conveniently confined in space, ... Read more

How to build a biological nanomachine Andela Saric , University College London The molecular machinery of life is largely created via self-organisation of individual molecules into functional larger-scaled structures. Such processes are multi-scale in nature and constantly driven far from thermodynamic equilibrium. Our group develops minimal coarse-grained computer models to help understand how the assembly ... Read more

How to build a biological nanomachine Andela Saric , University College London The molecular machinery of life is largely created via self-organisation of individual molecules into functional larger-scaled structures. Such processes are multi-scale in nature and constantly driven far from thermodynamic equilibrium. Our group develops minimal coarse-grained computer models to help understand how the assembly ... Read more

Alteraciones en el sistema melanopsínico en la retinosis pigmentaria y durante el proceso de envejecimiento Gema Esquiva , Universitat d'Alacant La retinosis pigmentaria es la degeneración hereditaria de la retina más frecuente, siendo la cuarta causa de ceguera en el mundo. Además, en esta enfermedad, se producen alteraciones en los ritmos circadianos, esenciales para llevar ... Read more

Alteraciones en el sistema melanopsínico en la retinosis pigmentaria y durante el proceso de envejecimiento Gema Esquiva , Universitat d'Alacant La retinosis pigmentaria es la degeneración hereditaria de la retina más frecuente, siendo la cuarta causa de ceguera en el mundo. Además, en esta enfermedad, se producen alteraciones en los ritmos circadianos, esenciales para llevar ... Read more

Translational chemistry, optical imaging and precision medicine Marc Vendrell , University of Edinburgh Optical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We ... Read more

Translational chemistry, optical imaging and precision medicine Marc Vendrell , University of Edinburgh Optical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We ... Read more