Highlights of 20 years DNP with Merck as partner Matthias Schulze, Merck Introduction of Merck’s capabilities to supply specifically labeled tracers in different grades. Describing the milestones of DNP towards establishing that method as a powerful tool in cancer diagnostics. Outlining the challenges and the scope on projects utilizing 13 C labeled reagents. Matthias Schulze ... Read more
Reprogramming the Factory of Life to Target the Delivery of mRNA via Helical Chirality Virgil Percec, Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia Homochiral helical self-organizations are known at the macroscopic level in nature, art, architecture and science for thousands of years . However, molecular helicity was discovered in proteins ... Read more
Biomaterials for cancer study and accelerate wound healing Dr. Andy Tay , Assistant Professor, Presidential Young Professor, Department of Biomedical Engineering Magnetic hydrogels are materials containing magnetic microparticles which help transduce magnetic fields into mechanical forces. In the presence of a static magnet, the stiffness of magnetic hydrogels can be altered to investigate the reversible ... Read more
Supercomputer-based virtual humans: the future of medicine NOW Mariano Vázquez, ELEM Biotech & Barcelona Supercomputing Center In this talk we are going to address the potential of supercomputer-based virtual humans for the biomedical realm. Virtual Humans are computational "avatars" of a patient, which combines data with a mathematical model which are used to predict (as opposed ... Read more
New technologies for accelerating drug discovery and preclinical testing Maria Majellaro, Chief Scientific Officer of Celtarys. Abi J Vazquez. Co-founder and COO of DIVERSA Technologies SL. Bruno K Rodiño-Janeiro, Chief Scientific Officer of BFlow. Celtarys, DIVERSA and BFlow belong to the Galician biotechnology ecosystem and are dedicated to provide cutting-edge technologies applied in different ... Read more
Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes Simone Reber, Max Planck Institut for Infection Biology, Berlin (invited by Pere Roca-Cusachs) The packing and confinement of macromolecules in the cytoplasm and nucleoplasm has profound implications for cellular biochemistry. How intracellular density distributions vary and affect cellular physiology remains largely unknown. We show that the ... Read more
Microfluidic technology enabling biomedical applications Jaap den Toonder, Microsystems Research Section, Department of Mechanical Engineering, and Institute for Complex Molecular Systems, Eindhoven University of Technology. Currently, visiting professor at IBEC, Barcelona Microfluidics is the science and technology of manipulating and analyzing fluid flow at small scales, typically from millimeters down to micrometers. At these scales, ... Read more
What can microfluidic technologies offer during self-assembly processes? Josep Puigmartí-Luis, Departament de Ciència dels Materials i Química Física, Institut de Química Teòrica i Computacional (invited by César Rodriguez-Emmenegger) Self-assembly has long being used to control covalent and non-covalent interactions where molecular design has been the major driving force to achieve a desired outcome. Like in ... Read more
Toward the next generation of 3D optical microscopes: faster, deeper, and label-free Martí Duocastella, Departament de Fisica Aplicada, Universitat de Barcelona Three-dimensional (3D) optical microscopy is the tool of choice for characterizing the structure and dynamics of biological systems at sub-cellular resolution. However, most microscope architectures are tailored to capture two-dimensional (2D) information from moderately ... Read more
Epithelial Cell Variability is Governed by Physics Principles and Has Mechanobiology Impacts Dr. Neil Lin, Assistant Professor of Mechanical Engineering and Bioengineering at University of California, Los Angeles (UCLA). Biological systems inherently exhibit variability, seen in diverse cell shapes, sizes, and mechanical properties. Despite its prevalence, our understanding of the role of phenotypic heterogeneity in ... Read more