PhD Discussions Session

Mechanical phenotyping of colorectal cancer patient derived organoids based on LGR5 expression Sefora Conti, Integrative cell and tissue dynamics group Colorectal cancer (CRC) tumors are composed by heterogeneous cell populations comprising differentiated cells and a small pool of cancer stem cells (CSCs). The link between cancer cell differentiation states and their metastatic potential has been ... Read more

Mechanical characterization of murine pluripotency dissolution Srivatsava Viswanadha Venkata Naga Sai, Cellular and Molecular Mechanobiology Group Mouse Embryonic Stem Cells (mESCs) can be maintained in ground/naïve state when grown in a defined N2B27 media with the supplementation of two inhibitors (2i) for MEK/Erk and GSK3β. Upon 2i withdrawal, mESCs exit naïve state and become functionally ... Read more