Irene Marco Rius
CV SummaryHer research develops tools based on magnetic resonance spectroscopy (MRS) and imaging (MRI) to gain insights on cellular metabolism and detect pathological changes, in order to identity biomarkers of disease for an early diagnosis and to evaluate treatment response short after therapy administration. Particularly, she has experience in the use of hyperpolarisation by dynamic nuclear polarisation to study disease in vivo, in real time and non-invasively.
Irene's team has currently three main research lines:
· Biomarker discovery in in vivo and in vitro models of diseases.
· MRS hardware and software development to monitor disease and evaluate drug response in situ, in organ-on-chip models.
· Metabolomic studies of clinical samples and body fluids ex-vivo.
She is a strong advocate of fostering scientific careers and the importance of science communication. She takes an active role in teaching and mentoring younger scientist from school age to PhD students, delivering talks on career development and talking to the public about her work.
Irene Marco is Junior group leader, "la Caixa" Foundation - BIST Chemical Biology Programme
Staff member publications
Yeste J, Azagra M, Ortega MA, Portela A, Matajsz G, Herrero-Gómez A, Kim Y, Sriram R, Kurhanewicz J, Vigneron DB, Marco-Rius I, (2023). Parallel detection of chemical reactions in a microfluidic platform using hyperpolarized nuclear magnetic resonance Lab On A Chip
Eills J, Picazo-Frutos R, Burueva DB, Kovtunova LM, Azagra M, Marco-Rius I, Budker D, Koptyug IV, (2023). Combined homogeneous and heterogeneous hydrogenation to yield catalyst-free solutions of parahydrogen-hyperpolarized [1-13C]succinate Chemical Communications 59, 9509-9512
Mouloudakis, Kostas, Bodenstedt, Sven, Azagra, Marc, Mitchell, Morgan W., Marco-Rius, Irene, Tayler, Michael CD., (2023). Real-Time Polarimetry of Hyperpolarized 13C Nuclear Spins Using an Atomic Magnetometer Journal Of Physical Chemistry Letters 14, 1192-1197
Herrero-Gomez, A, Azagra, M, Marco-Rius, I, (2022). A cryopreservation method for bioengineered 3D cell culture models Biomedical Materials 17, 045023
Herrero-Gomez, A, Azagra, M, Riba, A, Yeste, J, Marco-Rius, I, (2022). New cryopreservation method for 3d hepatocyte culture models (Abstract 2151) Tissue Engineering Part a 28, S611
Trueba-Santiso, A., Fernández-Verdejo, D., Marco Rius, I., Soder-Walz, J. M., Casabella, O., Vicent, T., Marco-Urrea, E., (2020). Interspecies interaction and effect of co-contaminants in an anaerobic dichloromethane-degrading culture Chemosphere 240, 124877