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Playing with molecular Lego to build the next generation of drug delivery vectors

albertazzi ACS nanoMany drugs are hindered in their therapeutic potential by issues such as too-fast clearance by the kidneys, undesirable properties, lack of selectivity, and poor internalization in the cell. Nanotechnology has the potential to alter the landscape of medicine by providing targeted solutions for the delivery of small-molecule drugs and biopharmaceuticals.

Now, new IBEC junior group leader Lorenzo Albertazzi and his former colleagues at the Eindhoven University of Technology, working together with industry partner Novartis, have made a leap in drug delivery vectors by developing a new type of carrier with some groundbreaking improvements.

Micromotors use surface variations for docking and guiding

Researchers at the Institute for Bioengineering of Catalonia (IBEC), the Max-Planck Institute for Intelligent Systems and the University of Stuttgart have revealed in an article in Nature Communications today that micromotors can be guided using tiny topographical patterns on the surfaces over which they swim.

Samuel Sánchez and Mykola Tasinkevych’s ‘microswimmers’ are usually guided through fluids using specially engineered magnetic multilayer coatings, which combined with external magnetic fields, helps to control their trajectory.

La Sexta Noche, 06-02-16

la sextaIBEC group leader and ICREA research professor Samuel Sánchez was one of two scientists taking part in a studio discussion on La Sexta Noche on Saturday, in a segment about what it’s like to be a talented young scientist or entrepreneur in the financial climate of Spain today.

“Envelliment humà, on estan els límits?”

ateneuOn Wednesday evening IBEC Director Josep Samitier will be a speaker at a free public lecture organised by the Secció de Ciència i Tecnologia de l’Ateneu Barcelonès as part of the association’s “+Humans: el futur de la nostra espècie” cycle.

In “Envelliment humà, on estan els límits?” Josep and another expert, Dr. Joan Guàrdia of the Institut de Recerca Cervell, Cognició i Conducta (IR3C) and psychology professor at the University de Barcelona, will share their views on human ageing, specificially the morphological and physiological changes that appear as a result of the action of time on human beings. The public event will will take place at the Sala Verdaguer of the Ateneu Barcelonès on Wednesday 10th February at 19:00.

“Seis aplicaciones robóticas que no conocías”

elpaisglobal robotSamuel Sánchez’s nanorobots are one of the “Seis aplicaciones robóticas que no conocías” described in an article in El Pais today.

Covering the recent Global Robot Expo in Madrid, at which Samuel was a speaker, the article explains the various applications for current research into robotics, including robots for therapy and rehabilitation, recycling, search and rescue, intelligent cities, agriculture and, of course, medicine.