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Drugging the undruggable: towards the development of selective modulators of cadherin-mediated cell-cell adhesion Emilio Parisi, Italian Institute of Technology (Milano) and Latvian Institute of Organic Synthesis (Riga) Cadherins are transmembrane calcium-dependent cell adhesion proteins that mediate cellular adherens junction formation and tissue morphogenesis. Loss of cadherin-mediated adhesion has been implicated in many different steps of ... Read more
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Drugging the undruggable: towards the development of selective modulators of cadherin-mediated cell-cell adhesion Emilio Parisi, Italian Institute of Technology (Milano) and Latvian Institute of Organic Synthesis (Riga) Cadherins are transmembrane calcium-dependent cell adhesion proteins that mediate cellular adherens junction formation and tissue morphogenesis. Loss of cadherin-mediated adhesion has been implicated in many different steps of ... Read more |
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