Semi-synthetic nucleosomes to stabilize and image enzyme-chromatin interactions Carlos Moreno Yruela, Researcher in Chemical Biology, EPFL, Switzerland Chromatin structure regulates gene expression and is tightly controlled by histone post-translational modifications. SIRT7 is a histone lysine deacylase found to maintain oncogenic gene expression profiles supporting tumor growth and metastasis. Interestingly, the activity of SIRT7 is fully ... Read more

Harnessing the power of stem cell therapy in an off-the-shelf nano-delivery platform for treating brain disorders Prof Marcelle Machluf, Faculty of Biotechnology and Food Engineering, Technion, Haifa, Israel Mesenchymal stem cells (MSCs) have gained the most attention in cell therapy, owing to their ability to traverse physiological barriers, and target different sites of inflammation including ... Read more

Advances in understanding and manipulating influenza A virus liquid inclusions Maria João Amorim, PhD, Group Leader, Cell Biology of Viral Infection Lab, Católica Biomedical Research Centre, Universidade Católica Portuguesa, and Instituto Gulbenkian de Ciência, Portugal Many viruses form biomolecular condensates de novo as part of their replication programmes. Influenza A virus is an important human pathogen ... Read more