Vaccinia in & as next-gen oncolytic virotherapy: exploiting the synergy between oncolysis and chemotherapy Dr Ernesto Mejías Pérez Ramón y Cajal researcher Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Universidad de Córdoba. Dpto. de Biología Celular, Fisiología e Inmunología In the fight against cancer, conventional treatments fall short of healthcare expectations. Oncolytic virotherapy is ... Read more

Molecular and mechanical regulation of abscission in stem cells Agathe Chaigne, PhD., Group leader. Cell Biology, Neurobiology and Biophysics department, Utrecht University, The Netherlands Abscission is the last step of cell division leading to the complete separation of the two sister cells and consists in the cutting of a cytoplasmic bridge. Abscission is mediated by ... Read more

Engineering enzymes for biomedical and biotechnological applications Emilio Parisini, Latvian Institute of Organic Synthesis (Riga, Latvia), University of Bologna (Italy) Enzyme engineering has the potential to improve the activity, the stability and the substrate recognition of enzymes. As such, it paves the way for the design of novel enzymes with improved performances for a wide ... Read more

Delivering effector molecules in cells in vitro and ex vivo by photoporation. Kevin Braeckmans, Biophotonics Research Group, Lab. General Biochemistry and Physical Pharmacy, Ghent University, Belgium Delivery of bioactive compounds, such as proteins and nucleic acids, into cells in vitro or ex vivo is a generic requirement for many applications in the life sciences, such ... Read more